Selected Publications

Selected Publications 

# Senior author

2021 - 2025

#11. Yan L, Liu JJ, Hong L#.  Pharmacol Res. (2025) "Hv1 channel in immune cells and pharmacology."

#10. Cao X, Darbar F, Wu X, Zhang L, Darbar D#, Hong L#.  Am J Cardiovasc Dis. (2025) "A novel gain-of-function mutation SCN5A-N470K associated with an African American familial atrial fibrillation."

#9. Cao X, Yan L, Hong L#.  Biochem Biophys Rep. (2025) "Ion channel mutations and cancer."

#8. Yan L, Zhang L, Ogunniyi K, Hong L#.  J Respir Biol Transl Med. (2024) "Ion channels in the immune response of asthma."

#7. Zhang L, Wu X, Hong L#.  Bioengineering. (2024) "Endothelial reprogramming in atherosclerosis."

#6. Zhang L, Wu X, Cao X, Rao K, Hong L#.  J Biol Chem. (2024) "Trp207 regulation of voltage-dependent activation of human Hv1 proton channel."

#5. Wu X, Singla S, Liu JJ, Hong L#.  Front Immunol. (2023) "The role of macrophage ion channels in the progression of atherosclerosis."

#4. Wu X, Zhang L, Hong L#. iScience (2022) "The role of Phe150 in human voltage-gated proton channel."

#3. Wu X, Li Y, Hong L#. Front Physiol. (2022) "Effects of mexiletine on a race-specific mutation in Nav1.5 associated with long QT syndrome." 

#2. Wu X, Li Y, Maienschein-Cline M, Feferman L, Wu L, Hong L#. Front Cell Dev Biol. (2022) "RNA-Seq analyses reveal roles of the HVCN1 proton channel in cardiac pH homeostasis." 

#1. Wu X, Hong L#. Int J Mol Sci. (2021) "Calmodulin interactions with voltage-gated sodium channels." 

Before 2021

Hong L#, Zhang M, Ly OT, Chen H, Sridhar A, Lambers E, Chalazan B, Youn SW, Maienschein-Cline M, Feferman L, Ong SG, Wu JC, Rehman J, Darbar D#. "Human induced pluripotent stem cell-derived atrial cardiomyocytes carrying an SCN5A mutation identify nitric oxide signaling as a mediator of atrial fibrillation." Stem Cell Reports (2021)

Hong L#, Zhang M, Sridhar A, Darbar D#. "Pathogenic mutations perturb calmodulin regulation of Nav1.8 channel." Biochem Biophys Res Commun. (2020)

Hong L. "Modeling atrial fibrillation with human iPSCs." J Cardiol. (2018)

Hong L. "Stem cell therapy: An emerging treatment approach for atrial fibrillation." Ann Cardiol Vasc Med. (2017)

Hong L, Tombola F. "Allostery: A lipid two-step." Nat Chem Biol. (2016)

Hong L, Singh V, Wulff H, Tombola F. "Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling." Sci Rep. (2015)

Hong L, Kim I, Tombola F. "Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives." PNAS (2014)

Highlighted in:  "In pursuit of an inhibitory drug for the proton channel." PNAS (2014)

Hong L, Pathak MM, Kim I, Ta D, and Tombola F. "Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains." Neuron (2013)

Highlighted in: "Common principles of voltage-dependent gating in Hv and Kv channels." Neuron (2013)

Hong L, Xie ZZ, Du YH, Tang YB, Tao J, Lv XF, Zhou JG, Guan YY. "Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis." Atherosclerosis (2011)

Hong L, Wang G, Guan Y. "Involvement of volume-regulated Cl- current in myocardial hypertrophy." Chin Pharmacol Bull. (2007)

See "A full list of publications"