Common Cold Unit

The Common Cold Unit (CCU) in Salisbury, Wiltshire, was a pioneering research facility dedicated to studying the common cold. Established in 1946 by the Medical Research Council (MRC), the unit was located at the site of the former Harvard Hospital at Harnham Down, which had been donated to the UK after World War II. The site was on the left at the top of Coombe Road as you leave Harnham towards Coombe Bissett.

Under the leadership of Sir Christopher Andrewes and later Dr. David Tyrrell, the CCU conducted extensive studies on the etiology, epidemiology, prevention, and treatment of the common cold. The unit was instrumental in identifying and isolating various cold viruses, including rhinoviruses, parainfluenza viruses, and notably, the first human coronavirus in 1965.

A hallmark of the CCU's research was its human challenge trials, where volunteers were deliberately infected with cold viruses to study the progression and potential treatments of the illness. Approximately 20,000 volunteers participated in these trials over the years, often staying for 10-day periods in isolated huts equipped with basic amenities. During their stay, volunteers were monitored closely by medical staff wearing protective gear.

The CCU operated until 1990, when the site was redeveloped into a housing estate known as Harvard Heights. Many of the roads are named after prominent members of staff. A commemorative plaque now marks the location, honouring the contributions of the volunteers and medical staff involved in the research. The work conducted at the CCU has had a lasting impact on the understanding and treatment of the common cold and respiratory viruses.

For more detailed information and photographs, you can visit the Salisbury Healthcare History website: Harvard Hospital – Common Cold Unit.