Welcome to the Gomes Lab!

The Gomes group develops mass-spectrometry (MS)-based strategies to elucidate the structure of intact proteins and their complexes within the cellular environment. Of great interest is to understand how protein structural deviations (e.g., posttranslational modifications, truncations, and mutations) and ligands (e.g., small molecule inhibitors, metals, and lipids) drive the activity, formation, and stability of functional protein assemblies. Our long-term goal is to understand the molecular basis of fundamental cellular processes to solve challenges in medicine.