Technologies developed and available for transfer are,
1. Small organic molecule fluorescent probe for detecting hypo- and hyper-cholesterolemia: Developed a non-enzymatic/metal-free small fluorescence probe for total cholesterol detection blood serum samples in collaboration with doctors from PGI, Chandigarh. (Indian Patent No. 202311086509).
2. First test-strip kit for naked-eye quantification of fluoride ion in water: We successfully demonstrated a new class of push-pull chromophores which can selectively sense fluorine anion in drinking water by naked-eye paper-based colorimetric detection without the need for any equipment (Indian Patent No. 202011028595). India Science TV Channel has reported a news coverage (documentary) on our technology related to equipment-free, instant paper-strip based Fluoride detection in water (news coverage: https://www.indiascience.in/videos/anusandhanika-episode-6-h). A startup company is being registered.
3. Tiny contribution towards low-cost drugs: The developed polymer-supported copper oxide nanoparticles catalyst and its applications in C-C and C-N bond-forming reactions have been successfully demonstrated with its use in Rufinamide drug industrial synthesis to bring down the cost. The rufinamide drug is an anti-convulsant and required to take the daily course for a lifetime, which puts the patient in to highly bothersome. (Indian Patent no. 201911042361). Also, future studies are directed towards other triazole drug molecules (Asian J. Org. Chem. 2021). (news coverage: https://dst.gov.in/inst-develops-nanotechnology-based-low-cost-method-production-antiepileptic-drug-rufinamide), Currently, a Bangalore based company is testing our catalyst for their industrial use to perform click reactions.
4. Solution for industry Effluent contamination: This technology was developed upon request from a Gujarat-based pharmaceutical company. One of the major contributors to environmental pollution is the pharmaceutical and chemical industries' effluent contamination in environmental water bodies. Developed a simple solution for recovering the slats and unreacted chemicals in a self-sustainable fashion. Though the invented technology is optimized for paracetamol industries, future development of optimization for specific industries can be fine-tuned to reach the vast number of other organic industries, to achieve zero waste sustainable process with revenue generating and environmental safety (patent filing under process).
5. Antimicrobial coating for Sutures: New type of polymeric biocide (100% drug units and having no spacer) was developed for antimicrobials coating of sutures (ACS Appl. Polym. Mater. 2022 Highlighted in the Front cover of the Journal; Photochem. Photobiol. 2024; Just accepted). Currently, we are in talks with an Israel-based company for developing an antimicrobial coating for surgical devices.
Chemical Industries convert raw materials into useful products that we use in daily life. This has brought a tremendous change in how the world operates. It is of utmost important for everyone to understand the importance of the chemical industries which have touched all our facets of life like Agriculture, Health, Environment, Food, Hygiene, Transportation, Decor, etc. Unfortunately, this also brings harmful effects such as pollution due to industrial waste contamination. As a chemist, while creating new advanced nanomaterials for making mankind and betterment of other living systems, We strongly believe that through our research even this negative effect can be tackled.
The companies interested may contact Dr. Jayamurugan (jayamurugan@inst.ac.in)
Media coverage:
Fluoride detection:
· News coverage on equipment-free, instant paper-strip-based fluoride detection. Various news media covered including India Science TV Channel Report on our technology related to Fluoride ion Sensing in water and telecasted the programme on August 15 2020 (URL: https://youtu.be/ljIcboFa34I)
https://dst.gov.in/equipment-free-simple-paper-strip-based-naked-eye-fluoride-ion-detection-and-quantification-kit
Rufinamide drug production:
· News coverage on Anti-epileptic drug " Rufinamide" synthesis
https://dst.gov.in/inst-develops-nanotechnology-based-low-cost-method-production-antiepileptic-drug-rufinamide
Biomass-based sun-screen (SS) lotion: News coverage: https://www.tribuneindia.com/news/chandigarh/tricity-businesswomen-shine-at-startup-summit-455120
