Meeting abstracts
Zhang G. Oxidized vegetable oil exaggerates colitis and colitis-associated colon tumorigenesis ACS Fall 2020 Virtual Meeting & Expo, 17-20 August 2020 (invited talk).
Zhang G. Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation. Bioactive Lipids in Cancer, Inflammation and Related Diseases International Conference. St. Petersburg, FL, 20-23 Oct. 2019 (oral presentation).
Zhang J., Edin M.L., Yang J., Sanidad K.Z., Sherman H., Wang W., Minter L.M., Hammock B.D., Zeldin D.C., and Zhang G. Excess intake of dietary linoleic acid exaggerates colon tumorigenesis: roles of cytochrome P450 (CYP) metabolites involved. Bioactive Lipids in Cancer, Inflammation and Related Diseases International Conference. St. Petersburg, FL, 20-23 Oct. 2019 (Poster).
Zhang G. Oxidized Dietary Fat: A Novel Risk Factor of Inflammatory Bowel Disease and Colon Cancer via Altering Gut Microbiota. AOCS National Meeting, St. Louis, MO, 5-8 May, 2019 (AOCS Young Scientist Research Award)
Wang Y., Wang W., Yang H., Shao D., Zhao X., and Zhang G. 4-HNE, an Endogenous Lipid Peroxidation Product, Exacerbates Colonic Inflammation through Activation of Toll-like Receptor 4 Signaling. AOCS Annual Meeting, St. Louis, MO, 5-8 May 2019.
Wang W, Yang J, Edin ML, Wang Y, Xiao H, Liu J, Hammock BD, Zeldin D, Zhang G. Targeted metabolomics identifies cytochrome P450 monooxygenase eicosanoid pathway as novel therapeutic target of colon tumorigenesis. AOCS National Meeting, St. Louis, MO, 5-8 May, 2019 (Health and Nutrition Division Student Excellence Award).
Zhang G. Environmental and dietary risk factors of colonic inflammation and colon cancer, The 2nd International Symposium on Food Nutrition and Health (ISFNH), 2018, Dalian, China, 14-16 September, 2018 (invited talk).
Zhang G. Oxidized Fat Increases Colitis and Colon Tumorigenesis through Activation of Toll-like Receptor 4 (TLR4) Signaling. Food & Function international symposium, 2018, Xi’an, China, 25-27 May 2018 (invited talk)
Sanidad K.Z., Gu M., Yang H., Karner E., Wang W., Zhang J., Xiao H., Zhang G. Exposure to antimicrobials found in the environment perturbs gut microbiota in mice in vivo and in human fecal bacteria ex vivo. NACSETAC 24th Annual Meeting & Short Course, Durham, NH, 21-23 May 2018 (Best Poster Award)
Zhang G. Dietary Intake of Mildly Oxidized Fat Increases Colitis and Colitis-associated Colon Tumorigenesis through Activation of Toll-like Receptor 4 (TLR4) Signaling. 2018 AOCS Annual Meeting & Expo, Minneapolis, MN, 6–9 May 2018 (invited talk and AOCS Junior Investigator Travel Award)
Zhang G. Lipidomic Profiling Identifies P450/sEH Pathway as a Novel Therapeutic Target for Colon Cancer. The 17th International Winter Eicosanoid Conference, Baltimore, MD, 11-14 March 2018 (invited talk)
Wang W., Yang J., Zhang J., Wang Y., Hwang SH, Qi W., Wan D., Kim D., Sun J., Sanidad K., Yang H., Liu Z., Liu J., Hammock B.D. and Zhang G. Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation. The 17th International Winter Eicosanoid Conference, Baltimore, MD, 11-14 March 2018 (Outstanding Poster Award)
Zhang J., Yang J., Wang W., Yang H., Sanidad K., Yang S-H., Sukamtoh E., Hammock B.D. and Zhang G.Pharmacological inhibition or genetic ablation of soluble epoxide hydrolase attenuates obesity-induced nonalcoholic fatty liver disease. The 17th International Winter Eicosanoid Conference, Baltimore, MD, 11-14 March 2018 (poster presentation)
Wang W, Wang Y, Edin M, Yang J, Yang H, Sanidad K, Wan D2, Song M, Xiao H, Liu Z, Liu J, Hammock B.D., Zeldin D and Zhang G. Lipidomic Profiling Identifies Cytochrome 450 as A Therapeutic Target for Colitis-Associated Colorectal Cancer. The 17th International Winter Eicosanoid Conference, Baltimore, MD, 11-14 March 2018 (poster presentation)
Yang H., Wang W., Romano K., Gu M., Sanidad K., Kim D., Yang J., Schmidt B., Panigrahy D., Pei R, Martin D, Ozay E., Wang Y., Song M., Xiao H., Minter L., Liu Z., Rey F. and Zhang G. Common Antimicrobials Triclosan Increases Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice. The Society of Toxicology 57th Annual Meeting and Tox Expo, San Antonio, TX, 11‒15 March 2018 (poster presentation)
Sanidad K.Z., Yang H., Wang W., Ozay E.I., Gu M., Karner E., Zhang J., Minter L.M., Xiao H., Zhang G. Consumer Antimicrobials Enhance Colitis and Colitis-associated Colon Tumorigenesis in Mice. The Society of Toxicology 57thAnnual Meeting and Tox Expo, San Antonio, TX, 11-15 March 2018 (poster presentation)
Wang W., Yang J., Edin M., Song M., Wan D., Xiao H., Liu J., Hammock B.D., Zeldin D.C., and Zhang G. Lipidomic profiling identifies cytochrome P450 epoxygenases as a novel therapeutic target of colorectal cancer. 15th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases, October 22-25, 2017, Puerto Vallarta, Mexico (invited talk and finalist of ERF Young Scientist Award).
Sanidad K.Z., Yang H., Wang W., Yang J., Kim D., Gu M,, Karner E., Ozay E.I., Minter, L.M., Xiao H., and Zhang G. Effects of antimicrobial ingredients benzalkonium chloride, benzethonium chloride, and chloroxylenol on colonic inflammation and colitis-associated colon tumorigenesis in mice. NESOT Annual Fall Meeting, Shrewsbury, MA, 20 October, 2017 (Best Student Oral Presentation Award)
Yang H., Wang W., Romano K., Gu M., Sanidad K.Z., Xiao H., Minter L.M., Liu Z., Rey F.E., and Zhang G. Common antimicrobial additive increases colonic inflammation and colitis-associated colorectal tumorigenesis in mice. NESOT Annual Fall Meeting, Shrewsbury, MA, 20 October, 2017 (Postdoctoral Poster Award)
Zhang G. Dietary intake of oxidized lipids exacerbates colon inflammation and colon cancer through activation of Toll-like receptor 4 (TLR4). 254th ACS National Meeting in Washington, DC, August 20-24, 2017 (invited talk and Travel Award of American Chemical Society).
Wang W., Yang J., Song M, Wan D., Yang H., Sanidad K., Hammock B.D., Xiao H, Liu Z, and Zhang G. Lipidomic profiling identifies cytochrome P450 as a therapeutic target for colitis-associated colorectal cancer. Experimental Biology National Meeting, Chicago, IL, 22-26 April, 2017 (oral and poster presentation)
Yang H., Wang W., Gu M., Sanidad K., Song M., Liu Z., Xiao H., Zhang G. Common antimicrobial additives increase colonic inflammation and colon tumorigenesis through modulation of Toll-like receptor 4 (TLR4) signaling. Experimental Biology National Meeting, Chicago, IL, 22-26 April, 2017
Sanidad K.Z., Wang W., Zhu J., Nimiya Y., Sukamtoh E., Du Z., and Zhang G. Manipulation of curcumin degradation to enhance its stability and biological activity. Experimental Biology National Meeting, Chicago, IL, 22-26 April, 2017 (poster)
Wang W., Yang H., Johnson D. Sanidad K., Sukamtoh E., Xiao H., Decker E., Zhang G. Oxidized corn oil increases colon inflammation and colon cancer. 2017 SRA conference, Amherst, MA, April, 2017 (oral finalist and poster presentation).
Zhang G. Cytochrome P450-derived fatty acid epoxides in pathology of colon cancer and obesity. 2016 International Symposium on PUFA and Metabolism, Tianjin, China, 22 Oct, 2016 (invited talk).
Nimiya Y., Wang W., Du Z., Sukamtoh E., Zhu J., Decker E. and Zhang G. Redox modulation of curcumin stability: redox active antioxidants increase chemical stability of curcumin. Experimental Biology National Meeting, San Diego, CA, 2-6 April, 2016
Wang W., Sukamtoh E., Xiao H. and Zhang G. Curcumin inhibits lymphangiogenesis in vitro and in vivo through suppressing VEGF receptor signaling. Experimental Biology National Meeting, San Diego, CA, 2-6 April, 2016
Wang W., Du Z., Nimiya Y., Sukamtoh E. and Zhang G. Allicin Inhibits Lymphangiogenesis in vitro and in vivo. Experimental Biology National Meeting, San Diego, CA, 2-6 April, 2016
Wang W., Yang J., Wang C., Tan B., Hammock B.D. and Zhang G. Oxylipin profiles of adipose tissues in obese mice: diols of polyunsaturated fatty acids. The 16th International Winter Eicosanoid Conference, Baltimore, MD, 13-16 March, 2016
Zhang G. P450-derived Eicosanoids on Cancer Progression. The 16th International Winter Eicosanoid Conference, Baltimore, MD, 13-16 March, 2016 (invited talk)
Wang W., Sukamtoh E., Xiao H. and Zhang G. Curcumin inhibits lymphangiogenesis in vitro and in vivo through suppressing VEGF receptor signaling. 2016 SRA conference, Amherst, MA, 8 April, 2016 (poster presentation).
Sukamtoh E., Sanidad K. Z., Wang W., Du Z., Florio E., He L., Xiao H., Decker E. A., and Zhang G. Quinone intermediate mediates cytotoxic effects of tert-butylhydroquinone (TBHQ). Undergraduate Research Symposium American Chemical Society National Meeting, San Diego, CA, 13-16 March, 2016 (Travel Award and 1st place of American Chemical Society Undergraduate Student Research Award Symposium)
Sukamtoh E., Sanidad K. Z., Wang W., Du Z., Florio E., He L., Xiao H., Decker E. A., and Zhang G. Oxidative conversion mediates anti-proliferative activities of tert-butylhydroquinone (TBHQ): structure and activity relationship study. 22nd Annual Massachusetts Statewide Undergraduate Research Conference, Amherst, MA, 22 April, 2016
Wang W., Johnson D. Sanidad K., Sukamtoh E., Xiao H., Decker E., Zhang G. Oxidized fish oil increases colon inflammation and colon cancer. 2016 Hultin Scholarship Competition, Amherst, MA, 5 Feb, 2016 (oral presentation)
Sukamtoh E., Wang W., Xiao H., and Zhang G. Effects and Mechanisms of Curcumin on Lymphangiogenesis in vitro. Undergraduate Research Competition Institute of Food Technologists National Meeting, Chicago, IL, 12-14 July, 2015 (Travel Award and 2nd place of IFT Undergraduate Research Competition)
Zhang G. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis and tumorigenesis. Experimental Biology National Meeting, San Diego, CA, April, 2014 (poster presentation).
Zhang G. Molecular mechanisms for the anti-angiogenic and anti-tumor effects of omega-3 fatty acid docosahexaenoic acid (DHA). 248th ACS National Meeting, San Francisco, CA, 10-14 August, 2014 (invited talk and Travel Award of American Chemical Society).
Zhang G. Molecular mechanisms for the anti-angiogenic and anti-tumor effects of omega-3 fatty acid docosahexaenoic acid (DHA). 248th ACS National Meeting, San Francisco, CA, 10-14 August, 2014 (Poster Presentation, Selected for SciMIx of 2014 ACS meeting).
Zhang G., Panigrahy D. and Hammock B.D. Soluble Epoxide Hydrolase on Angiogenesis, Tumor Growth and Metastasis. The 15th International Winter Eicosanoid Meeting, Baltimore, MD, 9-12 March, 2014 (invited talk).
Zhang G., Panigrahy D., Mahakian L., Yang J., Liu J., Lee K., Wettersten H., Ulu A., Hu X., Tam S., Hwang S., Ingham E., Kieran M., Weiss R.H., Ferrara K.W. and Hammock B.D. Epoxydocosapentaenoic acid (EDP): an omega-3 lipid mediator which inhibit angiogenesis, primary tumor growth and metastasis. Drug Discovery & Therapy World Congress, Boston, MA, 3-6 June, 2013 (invited talk and session co-chair).
Zhang G., Panigrahy D., Hwang S., Even L., Yang J., Liu J., Morisseau C., Inceoglu B., Ferrara K.W. and Hammock B.D. Soluble Epoxide Hydrolase as a Therapeutic Target for Cardiovascular Diseases and Cancer. FASEB Science Research Conferences, Phospholipid Metabolism: Disease, Signal Transduction, & Membrane Dynamics, Saxtons River, VT, 15-20 July, 2012 (invited talk).
Zhang G., Nitteranon V., Chan L.Y. and Parkin K.L. Comparative anti-inflammatory activities of ginger compounds: inhibition of NF-κB signaling through induction of oxidative stress. Institute of Food Technologies Annual Meeting, Chicago, IL, 17-20 July, 2010.
Zhang G. and Parkin K.L. Redox modulation as a mechanistic feature of biological effects of cysteine and glutathione mixed disulfide conjugates of Allium thiosulfinates. Experimental Biology National Meeting, Anaheim, CA, 24-28 April, 2010.
Zhang G. and Parkin K.L. A chemoenzymatic method to prepare gram-scale Allium organosulfur compounds and their presumptive metabolic products, and associated biological activities. Experimental Biology National Meeting, Anaheim, CA, 24-28 April, 2010.
Zhang G., Lee C. and Parkin K.L. Cellular biological activities of mixed disulfide conjugates of Allium thiosulfinates with cysteine and glutathione. Institute of Food Technologies Annual Meeting, Anaheim, CA, 6-10 June, 2009.
Parkin K.L., Rankin S.D. and Zhang G. Control of organosulfur transformation in Alliums through processing for retention and enhancement of health-related bioactivities. USDA National Research Initiative Project Director's Meeting, New Orleans, LA, 27-28 June, 2008.