Wang Z, He X, Zhang X, Spiegel J, Flynn SM, Balasubramanian S. Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras Nat Chem Mar 19 (2026 )

Rao SV, Young L, Cheeseman D, Flynn S, Krebs N, Couturier DL, Mack S, Brais R, Temple J, Smith A, Papachristou E, Pelicano C, Chilamakuri CSR, Herka K, Baba H, Farah L, Cheung PF, Siveke J, Guerrier S, Insolia L, Gill M, Archer Goode E, Kupczak S, Cheng Y, Borsari G, Jodrell D, D'Santos C, Russell A, Grünwald BT, Serrao E, Chernukhin I, Carroll JS. Transcription factor switching drives subtype-specific pancreatic cancer. Nat Genet 57:3016-3026 (2025)

Hardwick JS, Dhir S, Kirchner A, Simeone A, Flynn SM, Edgerton JM, Tavares RdCA, Esain-Garcia I, Tannahill D, Golder P, Monahan JM, Gosal WS & Balasubramanian S. SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands PNAS 122:e2512204122 (2025).

Doyle C, Herka K,  Flynn SM, Melidis L, Dhir S, Schoenfelder S, Tannahill D & Balasubramanian S. DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers Genome Biol 26:155 (2025).

Flynn SM, Dhir S, Herka K, Doyle C, Melidis L, Simeone A, Hui WWI, Tavares RdCA, Schoenfelder S, Tannahill D & Balasubramanian S. Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR Genome Biol 25:237 (2024).

Galli S, Melidis L, Flynn SM, Varshney D, Simeone A, Spiegel J, Madden SK, Tannahill D, Balasubramanian S. DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody J Am Chem Soc 144:23096-23103 (2022). 

Zyner KG, Simeone A, Flynn SM, Doyle C, Marsico G, Adhikari S, Portella G, Tannahill D, Balasubramanian S. G-quadruplex DNA structures in human stem cells and differentiation Nat Commun 13:142 (2022). 

Artan M, Barratt S, Flynn SM, Begum F, Skehel M, Nicolas A, de Bono M. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling J Biol Chem 297:101094 (2021).

Vuong-Brender TT, Flynn SM, Vallis Y, de Bono M. Neuronal calmodulin levels are controlled by CAMTA transcription factors Elife 10:e68238 (2021). 

Flynn SM, Chen C, Artan M, Barratt S, Crisp A, Nelson GM, Peak-Chew SY, Begum F, Skehel M, de Bono M. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity  Nat Commun 11:2099 (2020).