Orthopedic Applications
Orthopedic Applications
Embedded Files
Bone cells alter their cellular functions upon interacting with nanofeatured implant surfaces. To enhance integration of orthopedic implants with juxtaposed bone tissue, one of the main research thrusts of the Ercan Research Group is to fabricate nanofeatured surfaces on currently-used biomaterial surfaces. Through controlling surface topography, chemistry, wettability, crystallinity and other biomaterial related surface parameters, we are aiming to enhance osteointegration, and thus improve longevity of orthopedic and dental implants.
Bone cells alter their cellular functions upon interacting with nanofeatured implant surfaces. To enhance integration of orthopedic implants with juxtaposed bone tissue, one of the main research thrusts of the Ercan Research Group is to fabricate nanofeatured surfaces on currently-used biomaterial surfaces. Through controlling surface topography, chemistry, wettability, crystallinity and other biomaterial related surface parameters, we are aiming to enhance osteointegration, and thus improve longevity of orthopedic and dental implants.
Antibacterial Applications
Antibacterial Applications
Infections associated with medical devices are the leading cause of preventable deaths in hospitals. To fight against infections, antibiotics are the only tool in our arsenal. However, antibiotic treatment is ineffective against eradicating biofilms. Besides, the efficacy of antibiotics towards killing bacteria is decreasing based on the rise of multiple antibiotic-resistant bacteria strains, i.e. Methicillin Resistant Staphylococcus aureus. Towards fighting with infection, Ercan Research Group is designing antibacterial biomaterials to prevent growth of both gram positive and negative bacteria. We are utilizing nanotechnology-based tools to prevent attachment of bacteria onto implant surfaces, while controlled release of antibacterial agents (i.e. silver) prevent formation of biofilms on biomaterials.
Infections associated with medical devices are the leading cause of preventable deaths in hospitals. To fight against infections, antibiotics are the only tool in our arsenal. However, antibiotic treatment is ineffective against eradicating biofilms. Besides, the efficacy of antibiotics towards killing bacteria is decreasing based on the rise of multiple antibiotic-resistant bacteria strains, i.e. Methicillin Resistant Staphylococcus aureus. Towards fighting with infection, Ercan Research Group is designing antibacterial biomaterials to prevent growth of both gram positive and negative bacteria. We are utilizing nanotechnology-based tools to prevent attachment of bacteria onto implant surfaces, while controlled release of antibacterial agents (i.e. silver) prevent formation of biofilms on biomaterials.
Antibacterial Applications
Antibacterial Applications
Infections associated with medical devices are the leading cause of preventable deaths in hospitals. To fight against infections, antibiotics are the only tool in our arsenal. However, antibiotic treatment is ineffective against eradicating biofilms. Besides, the efficacy of antibiotics towards killing bacteria is decreasing based on the rise of multiple antibiotic-resistant bacteria strains, i.e. Methicillin Resistant Staphylococcus aureus. Towards fighting with infection, Ercan Research Group is designing antibacterial biomaterials to prevent growth of both gram positive and negative bacteria. We are utilizing nanotechnology-based tools to prevent attachment of bacteria onto implant surfaces, while controlled release of antibacterial agents (i.e. silver) prevent formation of biofilms on biomaterials.
Infections associated with medical devices are the leading cause of preventable deaths in hospitals. To fight against infections, antibiotics are the only tool in our arsenal. However, antibiotic treatment is ineffective against eradicating biofilms. Besides, the efficacy of antibiotics towards killing bacteria is decreasing based on the rise of multiple antibiotic-resistant bacteria strains, i.e. Methicillin Resistant Staphylococcus aureus. Towards fighting with infection, Ercan Research Group is designing antibacterial biomaterials to prevent growth of both gram positive and negative bacteria. We are utilizing nanotechnology-based tools to prevent attachment of bacteria onto implant surfaces, while controlled release of antibacterial agents (i.e. silver) prevent formation of biofilms on biomaterials.
Soft Tissue Applications
Soft Tissue Applications
Soft tissue repair requires biomaterials that can actively interact with cells and support dynamic healing processes. The Ercan Research Group develops advanced biomaterials for vascular, cardiac, neural, and skin tissue engineering applications. In the cardiovascular field, the group focuses on coronary stents, which are used to restore blood flow in arteries narrowed by atherosclerotic plaques. To improve stent integration with vascular tissue, stent surfaces are modified at the nanoscale to promote endothelial cell proliferation while reducing platelet adhesion and blood clot formation. The group also investigates the corrosion, ion/drug release, mechanical properties, and degradation behavior of stent materials. For neural, cardiac, and skin repair, biomaterials such as silk fibroin, chitosan, and collagen are engineered to regulate cellular responses, support extracellular matrix formation, and promote tissue regeneration. Through this integrated approach, the group seeks to enhance the biological performance and long-term integration of biomaterials for soft-tissue applications.
Soft tissue repair requires biomaterials that can actively interact with cells and support dynamic healing processes. The Ercan Research Group develops advanced biomaterials for vascular, cardiac, neural, and skin tissue engineering applications. In the cardiovascular field, the group focuses on coronary stents, which are used to restore blood flow in arteries narrowed by atherosclerotic plaques. To improve stent integration with vascular tissue, stent surfaces are modified at the nanoscale to promote endothelial cell proliferation while reducing platelet adhesion and blood clot formation. The group also investigates the corrosion, ion/drug release, mechanical properties, and degradation behavior of stent materials. For neural, cardiac, and skin repair, biomaterials such as silk fibroin, chitosan, and collagen are engineered to regulate cellular responses, support extracellular matrix formation, and promote tissue regeneration. Through this integrated approach, the group seeks to enhance the biological performance and long-term integration of biomaterials for soft-tissue applications.
Soft Tissue Applications
Soft Tissue Applications
Soft tissue repair requires biomaterials that can actively interact with cells and support dynamic healing processes. The Ercan Research Group develops advanced biomaterials for vascular, cardiac, neural, and skin tissue engineering applications. In the cardiovascular field, the group focuses on coronary stents, which are used to restore blood flow in arteries narrowed by atherosclerotic plaques. To improve stent integration with vascular tissue, stent surfaces are modified at the nanoscale to promote endothelial cell proliferation while reducing platelet adhesion and blood clot formation. The group also investigates the corrosion, ion/drug release, mechanical properties, and degradation behavior of stent materials. For neural, cardiac, and skin repair, biomaterials such as silk fibroin, chitosan, and collagen are engineered to regulate cellular responses, support extracellular matrix formation, and promote tissue regeneration. Through this integrated approach, the group seeks to enhance the biological performance and long-term integration of biomaterials for soft-tissue applications.
Soft tissue repair requires biomaterials that can actively interact with cells and support dynamic healing processes. The Ercan Research Group develops advanced biomaterials for vascular, cardiac, neural, and skin tissue engineering applications. In the cardiovascular field, the group focuses on coronary stents, which are used to restore blood flow in arteries narrowed by atherosclerotic plaques. To improve stent integration with vascular tissue, stent surfaces are modified at the nanoscale to promote endothelial cell proliferation while reducing platelet adhesion and blood clot formation. The group also investigates the corrosion, ion/drug release, mechanical properties, and degradation behavior of stent materials. For neural, cardiac, and skin repair, biomaterials such as silk fibroin, chitosan, and collagen are engineered to regulate cellular responses, support extracellular matrix formation, and promote tissue regeneration. Through this integrated approach, the group seeks to enhance the biological performance and long-term integration of biomaterials for soft-tissue applications.
Google Sites
Report abuse