Doug Weiser

RESEARCH FOCUS

Dr. Douglas C. Weiser's research focuses on understanding the molecular and cellular mechanisms that control cell shape, movement, and signaling during early vertebrate development, particularly during zebrafish gastrulation. His work explores how proteins like Gravin, Myosin Phosphatase, and septins regulate cell polarity, cytoskeletal dynamics, and morphogenetic movements essential for body axis formation. Additionally, he investigates how protein phosphatase-1 (PP1) and its regulators interact in signaling pathways that influence both normal development and disease processes, such as cancer metastasis and neurological disorders. His studies integrate developmental biology with cell signaling to uncover how precise protein interactions guide complex biological processes.