Publications

(most recent --> oldest)

Khan SH, Perkins AJ, Jawaid S, Wang S, Lindroth H, Schmitt RE, Doles J, True JD, Gao S, Caplan GA, Twigg HL 3rd, Kesler K, Khan BA. (2023) Serum proteomic analysis in esophagectomy patients with postoperative delirium: A case-control study. Heart Lung. 2024 Jan-Feb;63:35-41.

Dasgupta A, Gibbard DF, Schmitt RE, Arneson-Wissink PC, Ducharme AM, Bruinsma ES, Hawse JR, Jatoi A, Doles JD. (2023) A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer. Proc Natl Acad Sci U S A. Aug 22;120(34):e2215095120. 

Neyroud D, Laitano O, Dasgupta A, Lopez C, Schmitt RE, Schneider JZ, Hammers DW, Sweeney HL, Walter GA, Doles J, Judge SM, Judge AR. Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth. Commun Biol. 2023 May 13;6(1):519.

Schmitt RE, Dasgupta A, Arneson-Wissink PC, Datta S, Ducharme AM, Doles JD. Muscle stem cells contribute to long-term tissue repletion following surgical sepsis. J Cachexia Sarcopenia Muscle. 2023 Mar 8. doi: 10.1002/jcsm.13214.

Doles MD, Kang JY, Scholl LM, Doles JD. Leadership in PhD (LeaP): a longitudinal leadership skill building program for underrepresented biomedical research trainees. Front. Educ. 8:1063075. doi: 10.3389/feduc.2023.1063075

Nicolau S, Dasgupta A, Dasari S, Charlesworth MC, Johnson KL, Pandey A, Doles JD, Milone M. Molecular signatures of inherited and acquired sporadic late onset nemaline myopathies. Acta Neuropathol Commun. 2023 Jan 26;11(1):20. doi: 10.1186/s40478-023-01518-9.

Hogenson TL, Xie H, Phillips WJ, Toruner MD, Li JJ, Horn IP, Kennedy DJ, Almada LL, Marks DL, Carr RM, Toruner M, Sigafoos AN, Koenig-Kappes AN, Olson RL, Tolosa EJ, Zhang C, Li H, Doles JD, Bleeker J, Barrett MT, Boyum JH, Kipp BR, Mahipal A, Hubbard JM, Scheffler Hanson TJ, Petersen GM, Dasari S, Oberg AL, Truty MJ, Graham RP, Levy MJ, Zhu M, Billadeau DD, Adjei AA, Dusetti N, Iovanna JL, Bekaii-Saab TS, Ma WW, Fernandez-Zapico ME. Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers. JCI Insight. 2022 Nov 22;7(22):e158060. doi: 10.1172/jci.insight.158060.

Schmitt RE, Smith DY 4th, Cho DS, Kirkeby LA, Resch ZT, Liewluck T, Niu Z, Milone M, Doles JD. Myogenesis defects in a patient-derived iPSC model of hereditary GNE myopathy. NPJ Regen Med. 2022 Sep 9;7(1):48.

Cho DS, Schmitt RE, Dasgupta A, Ducharme AM, Doles JD. Acute and sustained alterations to the bone marrow immune microenvironment following polymicrobial infection. Shock. 2022 Jul 1;58(1):45-55. 

Arneson-Wissink PC, Doles JD. Quantification of Muscle Stem Cell Differentiation Using Live-Cell Imaging and Eccentricity Measures. Methods Mol Biol. 2022;2429:455-471. doi: 10.1007/978-1-0716-1979-7_31.

Dasgupta A, Arneson-Wissink PC, Schmitt RE, Cho DS, Ducharme AM, Hogenson TL, Krueger EW, Bamlet WR, Zhang L, Razidlo GL, Fernandez-Zapico ME, Doles JD. Anti-cachectic regulator analysis reveals novel Perp-dependent anti-tumorigenic properties of 3-methyladenine in pancreatic cancer. JCI Insight. 2021 Dec 7:e153842. doi: 10.1172/jci.insight.153842. 

Boehmer KR, Boschen De Souza SL, Doles JD, Lachman N, Mays D, Hedin KE, Dornink CA, Maher LJ and Lujan J (2021) Motivating Self-Efficacy in Diverse Biomedical Science Postbaccalaureate and Graduate Students Through Scientific Conference Implementation. Front. Educ. 6:774070. doi: 10.3389/feduc.2021.774070

Arneson-Wissink PC, Doles JD. Disrupted NOS2 metabolism drives myoblast response to wasting-associated cytokines. Exp Cell Res. 2021 Oct 1;407(1):112779. doi: 10.1016/j.yexcr.2021.112779.

Joseph J, Doles JD. Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook. Nutr Metab (Lond). 2021 Mar 25;18(1):33. doi: 10.1186/s12986-021-00565-0. 

Cho DS, Doles JD. Preparation of Adipose Progenitor Cells from Mouse Epididymal Adipose Tissues. J Vis Exp. 2020 Aug 25;(162). doi: 10.3791/61694.

Cho DS, Schmitt RE, Dasgupta A, Ducharme AM, Doles JD. Single cell deconstruction of post-sepsis skeletal muscle and adipose tissue microenvironments.  J Cachexia Sarcopenia Muscle 2020 Jul 8. doi: 10.1002/jcsm.12596.

Arneson PC, Hogan KA, Shin AS, Samani A, Jatoi A, Doles JD. The wasting-associated metabolite succinate disrupts myogenesis and impairs muscle regeneration. JCSM Rapid Communications. 2020 Jun 2. doi: 10.1002/rco2.14.

Arneson PC, Dusharme AM, Doles JD. A novel transplantable model of lung cancer associated tissue loss and disrupted muscle regeneration. Skeletal Muscle. 2020 Mar 9;10(1):6.

Cho DS, Lee B, Doles JD. Refining the adipose progenitor cell landscape in healthy and obese visceral adipose tissue. Life Sci Alliance. 2019. Nov 25;2(6). pii. e201900561.

Arneson PC, Doles JD. Impaired Muscle Regeneration in Cancer-Associated Cachexia. Trends Cancer. 2019 Oct;5(10):579-582.

Cho DS, Doles JD. Skeletal Muscle Progenitor Cell Heterogeneity. Adv Exp Med Biol. 2019 Aug;1169:179-193.

Joseph J, Cho DS, Doles JD. Metabolomic Analyses Reveal Extensive Progenitor Cell Deficiencies in a Mouse Model of Duchenne Muscular Dystrophy (2018). Metabolites. Oct 3;8(4). pii: E61. doi: 10.3390/metabo8040061. 

Doles JD, Hogan KA, O'Connor J, Wahner Hendrickson AE, Huston O, Jatoi A. Does the Poly (ADP- Ribose) Polymerase Inhibitor Veliparib Merit Further Study for Cancer-Associated Weight Loss? Observations and Conclusions from Sixty Prospectively Treated Patients (2018). J Palliat Med. Sep;21(9):1334-1338. doi: 10.1089/jpm.2018.0023. 

Tarragó MG, Chini CCS, Kanamori KS, Warner GM, Caride A, de Oliveira GC, Rud M, Samani A, Hein KZ, Huang R, Jurk D, Cho DS, Boslett JJ, Miller JD, Zweier JL, Passos JF, Doles JD, Becherer DJ, Chini EN. A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline (2018). Cell Metab. May 1;27(5):1081-1095.e10. doi: 10.1016/j.cmet. 2018.03.016. 

Hogan KA, Cho DS, Arneson P, Samani A, Palines P, Yang Y, Doles JD. Tumor- derived cytokines impair myogenesis and alter the skeletal muscle immune microenvironment (2017). Cytokine. Nov 16. pii: S1043-4666(17)30348-4. DOI: 10.1016/j.cyto.2017.11.006.

Carr RM, Enriquez-Hesles E, Olson RL, Jatoi A, Doles J, Fernandez-Zapico ME. Epigenetics of cancer- associated muscle catabolism (2017). Epigenomics. Sep 25. DOI: 10.2217/epi-2017-0058. 

Cho DS, Doles JD. Single cell transcriptome analysis of muscle satellite cells reveals widespread transcriptional heterogeneity (2017). Gene. Sep 8. pii: S0378-1119(17)30723-0. DOI: 10.1016/j.gene.2017.09.014. 

Postdoctoral

Hall MN, Hall JK, Cadwallader AB, Pawlikowski BT, Doles JD, Elston TL, Olwin BB. Transplantation of Skeletal Muscle Stem Cells (2017). Methods Mol Biol. Mar;1556:237-244. DOI: 10.1007/978-1-4939- 6771-1_12. 

Doles JD, Olwin BB. Muscle stem cells on the edge (2015). Current Opinion in Genetics and Development. Review. DOI: 10.1016/j.gde.2015.06.006. 

Hausburg MA*, Doles JD*, Clement S, Cadwallader AB, Hall MN, Blackshear PJ, Lykke-Andersen J, Olwin BB. *Equal contributors. Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay (2015). eLife. Mar 27;4. DOI: 10.7554/eLife.03390. 

Doles JD, Olwin BB. The impact of JAK-STAT signaling on muscle regeneration (2014). Nat Med. Oct 8;20(10):1094-5. Commentary. DOI: 10.1038/nm.3720

Bernet JD, Doles JD, Hall JK, Tanaka KK, Carter TA, Olwin BB. p38 MAPK signaling underlies a cell- autonomous loss of stem cell self-renewal in skeletal muscle of aged mice (2014). Nat Med. Mar;20(3):265-71. 10.1038/nm.3465 

Doles J, Keyes WM. Epidermal stem cells undergo age-associated changes (2013). Aging (Albany NY). 5(1):1-2. PMID: 23474601. Commentary. 

Doles J, Storer M, Cozzuto L, Roma G, Keyes WM. Age-associated inflammation inhibits epidermal stem cell function (2012). Genes Dev. 26(19):2144-53. DOI: 10.1101/gad.192294.

PhD and earlier

Doles J, Oliver T, Cameron E, Hsu G, Jacks T, Walker GC, Hemann MT. Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy (2010). Proc Natl Acad Sci U S A. 107(48):20786-91. DOI: 10.1073/pnas.1011409107.

Xie K*, Doles J*, Hemann MT, Walker GW. *Equal Contributors. Error-prone translesion synthesis mediates acquired chemoresistance (2010). Proc Natl Acad Sci U S A. 107(48):20792-7. DOI: 10.1073/pnas.1011412107.

Doles J, Hemann MT. Nek4 status differentially alters sensitivity to distinct microtubule poisons (2010). Cancer Res. 70(3):1033-41. DOI: 10.1158/0008-5472.CAN-09-2113. 

Burgess DJ, Doles J, Zender L, Xue W, Ma B, McCombie WR, Hannon GJ, Lowe SW, Hemann MT. Topoisomerase expression levels determine chemotherapy response (2008). Proc Natl Acad Sci U S A. 105(26):9053-8. DOI: 10.1073/pnas.0803513105. 

Doles J, Cook C, Shi X, Valosky J, Lipinski R, Bushman W. Functional compensation in Hedgehog signaling during mouse prostate development (2006). Dev Biol. 295(1):13-25. DOI: 10.1016/j.ydbio.2005.12.002. 

Lipinski RJ, Gipp JJ, Zhang J, Doles JD, Bushman W. Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling (2006). Exp Cell Res. 312(11):1925-38. DOI: 10.1016/j.yexcr.2006.02.019. 

Doles JD*, Vezina CM*, Lipinski RJ, Peterson RE, Bushman W. *Equal contributors. Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro (2005). Prostate. 65(4):390-9. DOI: 10.1002/pros.20321. 

Lovich MA, Doles J, Peterfreund RA. The Impact of Carrier Flow Rate and Infusion Set Dead-Volume on the Dynamics of Intravenous Drug Delivery (2005). Anesth Analg. 100(4):1048-55. DOI: 10.1213/01.ANE.0000146942.51020.88.