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Taking a look at a study published in the Journal of Hospital Medicine reporting reduced mortality in patients on glucocorticoid therpay with a decrease in CRP >50%
COVID CRP Reduction and Mortality_PICO.pdfBaricitinib PICO Question.pdfTaking a look at a study that compared baricitinib + remdesivir to remdesivir alone. Had some improvement in time to recovery in the combination group.
Taking a look at intermittent vs. continuous dosing in upper GI bleeding
Intermittent vs Continuous PPI for GI Bleed.pdfREDUCE Trial_PICO Question.pdfTaking a look at the trial that shaped the GOLD guideline recommendation regarding glucocorticoid duration for acute COPD exacerbation to 5-7 days.
Taking a look at the CHANCE and POINT trial
PICO - POINT and CHANCE.pdfAntibiotic Timing in Severe Sepsis and Septic Shock.pdfLooking at early administration of antibiotics in severe sepsis and septic shock. Here is also a Link to a recent Curbsiders podcast on antibiotics https://thecurbsiders.com/podcast/284
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