On my GitHub page you can find some Sage programs that compute the Delta dissimilarity measure and uberhomology for graphs (see this paper for details!).
The programs listed below are interactive (just modify the input and press "Evaluate"), but for longer computations you might want to download the code and run it locally.
Compute the Alexander polynomial for 2-bridge knots, and determine if they're smoothly slice
For a given sum of lens spaces find out the unique minimal representative up to rational homology cobordism