Nonstructural protein 3

Domains

Ubiquitin-like domain 1 (Ubl1) Residues 1-108

Macrodomain I (Mac1) Residues 207-386

SARS-Unique Domain (SUD) Residues 384-745 

Ubiquitin-like domain 2 (Ubl2) Residues 746-805 

Papain-like protease (PLpro) Residues 806-1058

Nucleic-acid binding domain (NBD) Residues 1059-1200

Marker domain (MD) Residues 1201-1340

Transmembrane domain (TM) Residues 1341-1567

Y domain Residues 1568-1945 

Subdomains

SARS-Unique Domain (SUD)

Macrodomain II (Mac2) Residues 387-548

Macrodomain III (Mac3) Residues 549-676 

Domain preceding Ubl2 and PL2pro (DPUP) Residues 677-745 

Papain-like protease (PLpro)

N-terminal ubiquitin-like domain (UBL) Residues 1-61

C-terminal ubiquitin-specific protease domain (USP) Residues 62-315