Nonstructural protein 12

SARS-CoV-2 nsp12

PDB ID: 6XEZ

Sequence length: 932 amino acids

RNA-dependent RNA polymerase (RdRp)

UniProt ID: P0DTD1

Domains

NiRAN Residues 117-250

Interface Residues 251-365

RdRp Residues 367-932

Subdomains

RdRp

Finger Residues 367-581, 621-679

Palm Residues 582-620, 680-815

Thumb Residues 816-932

Active sites

NiRAN Motifs AN, BN, CN

RdRp finger subdomain Motifs A, B, C, D, E

Palm subdomain Motifs F and G

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