Biochemistry I

Interesting links:

Genetics science learning center - excellent interactive ways to learn a variety of topics

Miscellaneous

Electron transport chain

ATP synthase in action

F0/F1 ATPase and ATP production

Chapter 8 - Nucleotides and Nucleic Acids

Phosphoramide method - Chemical synthesis of DNA

Polymerase chain reaction

Sanger sequencing method - another good video

Advanced sequencing technologies:

Reversible terminator sequencing

SMRT sequencing – Single Molecule Real-Time sequencing

Excellent lecture from MIT

Chapter 6 - Enzymes

How enzymes work

Michaelis-Menten kinetics overview

Chapter 5 - Protein Function

Protein-ligand binding - binding affinity and hill equation

Hemoglobin and Myoglobin - similarities and differences

Oxygen dissociation curve - Bohr effect

Hemoglobin oxygen binding cooperativity

Sickle cell anemia and hemoglobin

Western blotting

How does a muscle contract?

Cool animation

Chapter 4 - Three Dimensional Structure of Proteins

Phi-Psi angles and Ramachandran plot - interactive

Experimental techniques to characterize protein 3D structures

Introduction to X-ray crystallography  - video 1, video 2

Introduction to NMR spectroscopy

Introduction to 3D electron microscopy

Chapter 3 - Amino acids, Peptides and Proteins

Introduction to amino acids

Calculating the pI of amino acids

Protein purification techniques

Protein structure - primary to quaternary structure

Gel electrophoresis and SDS-PAGE