Chen Lab at ICOB

Zebrafish model in regeneration research

About the Chen Lab

Some vertebrates, like salamanders and zebrafish, are able to regenerate complex tissues (e.g. the appendages, major organs, and spinal cord). Understanding how and why natural regeneration occurs in these vertebrates may transform medicine as we know it today. Finding answers to these two questions is the basis of my research program.

We focus our efforts on key knowledge gaps that would be best addressed with the zebrafish model. We aim to combine large-scale cell imaging and genetics with systems-level analyses for uncovering the cellular and molecular mechanisms of regeneration. The long-term goal of my lab is to translate our findings for enhancing regenerative capacity of human tissues and organs.

實驗室的目標

某些脊椎動物像是蠑螈和斑馬魚有很強的再生能力這些動物可以再生複雜組織 像是身體肢體主要器官或是脊柱神經了解再生過程是如何發生? 為什麼這些動物有很強的再生能力? 回答這兩個問題是我們實驗室所有研究計畫的核心

我們利用斑馬魚作為模式生物的優勢開發新型的細胞標誌工具和影像平台結合大尺度多維度的細胞行為分析和遺傳學方法從個體的角度, 系統性地解構再生反應的細胞和分子機制 實驗室的長期目標是發展應用我們的研究成果, 增強人類組織和器官的再生能力

Latest news

2022/08/20: Congratulations to Keat Ying and Uday for receiving best poster awards in the 2022 International Conference of Taiwanese Society of Developmental Biology.

2022/03/10: Congratulations to Keat Ying for an imaging study accepted in Nature.

2022/01/28: Congratulations to Marco for receiving the oral presentation award in the 2022 Taiwan Physics Society conference.

2021/11/27: Congratulations to Uday for receiving the Gold Medal Award in the 2021 Taiwan Olympus Microscope Image Contest.

2021/11/27: Congratulations to Yuh, Keat Ying, and Uday for receiving presentation awards in the 2021 Taiwan zebrafish symposium.

2021/10/21: Congratulations to Keat Ying and Uday for receiving presentation awards in 2021 International Conference of Developmental Biology, Stem Cells and Regenerative Medicine.

2021/08/20: Congratulations to Yuh for an imaging study accepted in Development.

2021/07/05: Congratulations to Alan for a mutant study accepted in Development.

2020/12/10: Congratulations to Marco, Keat Ying, and Uday for receiving presentation awards in the TIGP-MBAS retreat.

2020/11/28: Congratulations to Uday, Alan, and Fio for receiving presentation awards in the 2020 Taiwan zebrafish symposium.

2020/06/08: We welcome Michael Wen, Longan Su, and Jade Hsu joining the lab as summer interns.

2019/11/22: Congratulations to Marco for receiving the best performance award in 2019 TIGP-MBAS retreat.

2019/11/16: Congratulations to Keat Ying, Yuh, and Alan for receiving best flash talk awards in 2019 Taiwan zebrafish meeting.

2019/11/07: Congratulations to Keat Ying, Marco, and Lisa for receiving poster awards in 2019 ICOB poster competition.

2019/10/30: Congratulations to Lisa and Alan for a mutant study accepted in Current Biology.

2019/08/24: Congratulations to Keat Ying for receiving a poster award in 2019 Joint Conference of Taiwanese Society of Developmental Biology and Taiwan Society for Stem Cell Research.

2019/07/01: We welcome Lu Wu and 顏薇珉 joining the lab as summer interns.

2018/12/10: Congratulations to Marco for receiving the award for the best oral presentation and Keat-Ying for receiving awards for the best flash talk and the best poster presentation in 2018 Taiwan zebrafish symposium.

2018/07/06: We welcome Claudia Lacombe, Yew Hong Wen, and 唐晏鍾 joining the lab as summer interns.

2018/04/09: We welcome Uday Kumar from TIPG-MBAS program joining the lab.

2018/03/05: We welcome Chung-Han Wang joining the lab.

2018/02/22: We welcome Keat Ying Chan from TIPG-MBAS program joining the lab for rotation.

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Nature 2022 May; 605 (7908): 119-125

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20220316-lab celebration

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Development 2021 Sep 15; 148 (18)

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Development 2021 Aug 1; 148 (15)

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20210408- Image by Uday Kumar (Chen Lab)

20210408- Image by Keat Ying Chan (Chen Lab)

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Current Biology 2019 Dec 16; 29 (24)

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