Open Positions

We are actively recruiting postdoc fellows, staff scientists and graduate students in Computational Biology. The primary focus of the laboratory is to drive mechanistic understanding and therapeutic insights of cancer and other complex diseases by extensively exploring large-scale multiomics data. We are particularly interested in coupling next generation sequencing-based genomics and mass spectrometry-based proteomics to characterize disease genomic abnormalities and seamlessly interpret their functional outcomes. Several immediate subjects to be tackled are: 1) tumor antigens 2) proteomics-driven cellular pathway interpretation 3) interpatient cancer heterogeneity and precision oncology. Our ways to conduct fruitful basic and translational research involve developing computational methods, performing integrative data analysis, as well as collaborating with experimental biologists and clinicians. The PI has expertise on experimental biology and data sciences and demonstrated strong productivity on both sides. During Ph.D. and postdoc, Dr. Huang has first- and cofirst-authored high impact papers published in Dev Cell (2018 and 2020), Cancer Cell (2021), and Cell (2019 and 2021), and middle-authored multiple others in top-tier journals. Together with nationwide collaborators, our lab is committed to guide trainees to develop strong research expertise and carve successful career paths. 

 

Ideal candidates would have:

1) Ph.D. (for postdoc applicants) or BS/MS (for staff scientists) in bioinformatics, computational biology, genetics, cancer biology and other relevant disciplines.

2) Proficiency in programming with R and/or python (for postdoc and staff scientists).

3) Self-motivation and strong interests in biology and data sciences, open mind, and abilities in fast learning.

 

The following background is considered as a plus:

1) Hands-on experience in machine learning and deep learning.

2) Knowledge and experience in analyzing MS proteomics, scRNA-seq or long-read seq data.

3) Demonstrated research achievements in bioinformatics.

 

The positions for postdoc and staff scientists are for 2-3 years with possible extension. The salary will be based or above the NIH guidance (commensurate with experience). To apply, please email to Dr. Huang (huangc@uab.edu) with current CV and contacts for 2-3 references, and a brief description of training background and career plans.


For graduate students, no research experience is required. Nonetheless, we expect graduate students to have a strong interest in bioinformatics and a commitment to learn programming and statistics and conduct independent research (whenever ready).

 

We are located in downtown Birmingham, a very nice and quiet not-so-small city to live and do science. UAB is ranked #20 of all U.S. institutions and universities in annual NIH funding. UAB School of Medicine is ranked consistently within the 30th place for research in US Best Medical Schools. The laboratory is affiliated to the Department of Genetics and the O’Neal’s Cancer Center, both of which are loaded with full momentum and ambitious growth plans in the coming years.