Wednesday

R. Dembinski, Organizer

M. Tanasova, Presiding

8:25 Introductory Remarks.

8:30 72. Fleximers – a strategic approach to broad-spectrum antiviral therapeutics. K.L. Seley-Radtke

9:05 73. Amide-modified RNA: synthesis, structure, and biological activity. E. Rozners

9:40 Intermission.

10:00 74. Expanding the Medicinal Chemist’s Toolbox Using Parallel Library Synthesis. J.M. Young

10:20 75. Photochemical method towards 2-azanorbornane scaffolds. A.E. Tharp, A. Allen, C. Stephenson

10:40 76. Combating Drug Resistance to Anti-Cancer Agents by Combining Organic and Biological Chemistry in the Drug Discovery Process. A. Berdis

C. D. Emal, Organizer, Presiding

G. Wilmes, Presiding

8:25 opening remarks.

8:30 77. Kinetic study of brewing hops α-acid isomerization by nuclear magnetic resonance spectroscopy. W. Fink, G. Wilmes

8:55 78. Determination of change in bitterness units throughout production and fermentation of beer using ultraviolet spectroscopy. A.S. Havens, K. Kean, C.D. Emal

9:20 79. Withdrawn

9:45 Intermission.

9:55 80. Using complex microbial communities to identify silent biosynthetic gene clusters. P. A Price

10:20 81. Molecular profiling of varietal honeys using nuclear magnetic response spectroscopy. C.D. Emal, O. Wakeham, J. Norris

10:45 82. Fermenting Alternative Sugars: There’s Gold in Them Thar Trees!. N.A. Powell

R. Armitage, Organizer, Presiding

D. M. Fraser, Presiding

8:20 Introductory remarks.

8:30 65. Multi-analytical Characterization of Beads from an Andean Inca Chullpa Funerary Assemblage. A. Bonneau, H. Walder, B. Carter, R. Armitage, W. Lovis

8:55 66. Ten years of characterization and dating on San rock art: paint recipes, coloring material processes and chronologies. A. Bonneau, D.G. Pearce, P. Mitchell, T. Higham

9:20 67. Trace organic analysis of oxalate rock coatings from Australia and Texas. J. Russ, H. Green, A. Gleadow

9:45 Intermission.

9:55 68. Withdrawn

10:20 69. Identifying blood as heme or hemoglobin in cultural heritage objects. D.M. Fraser

10:45 70. Radiocarbon Dating of Soot Encrustations from Grotte Mandrin: Comparing Plasma-Chemical Oxidation and ABA-Combustion Pretreatment Methods for Sample Preparation. R. Armitage, S. Vandevelde, J. Bond, A. Bonneau

11:10 Intermission.

11:20 71. First draught: Combining experimental archaeology and chemistry to investigate ancient alcohol. J. Driscoll

P. J. Dobrowolski, Organizer

M. A. Walters, Presiding

9:00 Opening remarks.

9:05 83. Tales of tau: Synaptic control using protease inhibitors. M.A. Walters

9:45 84. Adventures beyond Ann Arbor in phenotypic drug discovery: Application of whole-animal behavorial assays in the discovery of novel psychiatric drug candidates. N.A. Powell

10:25 Intermission.

10:35 85. Discovery chemistry to process chemistry Challenges, tools and solutions during this important transition. J. Graham

H. A. Lindsay, Organizer

11:30 - 1:30

86. Attachment of a platinum agent to the anticancer peptide D-CDT. D. Alomari, H. Evans, J. Guthrie, D. Heyl

87. Structural analysis of the 5' and 3' untranslated regions of SARS-CoV-2. S. Leskaj

88. Withdrawn

89. Bioconjugation of 4-Phenylbutyric Acid (4-PBA) to Gold Nanoparticle. K. Bandyopadhyay, T. Athavale, D. Al-Rasool, Z. Zhang

90. Relating Structure and Color in Azo Dyes. M.R. Hargittai, R. Edgington

91. Structural and kinetic studies of a minimal protein-only RNase P. S. Brotzman, C. Wilhelm, L. Mallik, M. Koutmos

92. X-Ray Crystallographic Structure of Methylglyoxalase A from Bacillus licheniformis. H.J. Krzysik, P.D. Cook

93. Investigation of hydrogen bonding in Riboflavin and Riboflavin Binding Protein interactions. D. Nichols, G. Bousquette, S. Marincean, M. Benore

94. Measurement of UHRF1 and UHRF2 Interaction with Nucleosomes. M. Kostoff, B. Albaugh

95. Synthesis and functionalization of biochemically relevant molecular probes through dehydrative arylation. M. Huynh, J. Truong

96. Universal fentanyl assay through differential impedance analysis for point-of-care testing. C. Alexopoulos, R. Aqrawi, Z. Wang

97. Isatin derivatives as potential antimicrobials. A. Richardson, M. Duvall, H.A. Lindsay

98. Effects of Proteins on Hop Utilization Efficiency. M. Miller, C.S. Hamilton

99. Tuning the magnetic properties of coupled di-Blatter radicals. D.B. Lawson, G. Flores, C.P. Constantinides

100. Synthesis of the dibenzoxepinone precursor of doxepin from salicylic acid. A. Martin, R. Turner

101. Development of a CVD System for Photocatalytic Thin Films. B. Platte, K.J. Boyd

102. In situ Generated Surface-bound Palladium-Gold Bimetallic Nanoparticles and their Potential towards Electrochemical Alcohol Oxidation. A. Ramadan, M. Obeidat, K. Bandyopadhyay

103. Optimization of the Synthesis of benzyloxypyridine as an undergraduate organic lab experience: Using NMR spectroscopy to compare reaction rates. A. Gullion, P.A. Albiniak

104. Synthesis of Oxindole Alkaloids and Investigation of Their Biological Activity. K. Reiland, T.J. Eckroat

105. Halogen Mediated Alkene Difunctionalization to Synthesize Medicinally Relevant Chemical Structures. L.P. Roberts

106. The Synthesis and Characterization of Chiral Guanidine-Based Four-Coordinate Tripodal Ligand DPI3tren for Copper-Catalyzed Atom Transfer Radical Polymerization. A.M. Al-Tamimi, R.C. Scarrow

107. Techniques for improving mechanical and material properties of potato starch bio-based plastic film. R. Singh, J. Staker, K. Collier, S. Franklin, A.P. Siegel, A. Tovar

108. Evaluation of potato starch-based plastic for use in liquid deposition modeling. J. Staker, R. Singh, K. Collier, M. Sosa, S. Franklin, A.P. Siegel, A. Tovar

A. Adhikary, Organizer, Presiding

1:30 Opening remarks.

1:35 126. In-operando X-ray absorption spectroscopic study of the reductive desorption of alkanethiol self-assembled monolayers on gold surfaces. L. Shi, B. Bonsall, A. Deb, C.C. McCrory, J.E. Penner-Hahn

1:55 127. Probing vibrational anhamonicity of a hydrogen-bonded molecular ferroelectric material 2-methylbenzimidazole. S.T. Wanasinghe, A. Sanni, S.N. Lavan, A. Rury

2:15 128. Investigation of competing excited-state deactivation processes of benzofluorenone derivatives using steady-state and time-resolved spectroscopy.. N.M. Dickson- Karn, T.C. Celius, B.W. Williams, J. Napoli, R.J. Black, K. Colley, T. Dunn, Y. Shi

B. Albaugh, Organizer

S. Backues, Organizer, Presiding

J. M. Holub, Presiding

1:30 Opening Remarks.

1:35 115. Monitoring ligand mediated helix transitions within the human estrogen receptor α using bipartite tetracysteine display.. J.M. Holub

2:05 116. Isatin-linked thiazolines, imidazolines, and benzothiazoles for inhibition of acetylcholinesterase. T.J. Eckroat

2:35 117. Development of photo-affinity label peptides for mapping therapeutically-relevant protein-protein interactions. K. Nahar, J.M. Holub

2:50 118. Probing the catalytic interactions of ketosynthases using near-natural substrate analogs. T.J. Boram, J. Lohman

3:05 Closing Remarks.

R. Dembinski, Organizer

N. K. Beyeh, Presiding

1:20 Introductory Remarks.

1:25 109. Targeting the undruggable through proteasome activation. J.P. Tepe

2:00 110. Total synthesis of thiazoline/thiazole containing peptide natural products’ via novel dehydrative approach. R. Morsy, J. Stockdill

2:20 111. Carbazole based neuroprotective multifunctional dopamine agonists as potential disease modifying treatment agents for Parkinson’s disease. A. Elmabruk

2:40 Intermission.

3:00 113. Targeting the aggregation of αA66−80 peptide related to cataracts with ionic macrocycles. N.K. Beyeh

3:30 114. Harnessing heterocyclizations for greener peptide synthesis. J.L. Stockdill

R. Armitage, Organizer, Presiding

D. M. Fraser, Presiding

1:30 Introductory remarks.

1:40 119. Bioarchaeological analysis and carbon dating of human remains found under a downtown Detroit sidewalk. M. Moore, C. Muzzin

2:00 120. Residue Analysis of Greco-Roman "Perfume" Bottles: A Collection of Double Unguentaria from the Michael C. Carlos Museum. S.J. Mahan, R. Armitage, R. Stein, M. Faass

2:20 121. Geochemistry and mineralogy of prospective sedimentary resources used in the last millennium BCE pottery production in the Eastern Adriatic. E. Doyle, M. Ugarković, B. Šegvić

2:40 122. Residue from an Old Kingdom Mummy: A Study on Mummification Practices in Ancient Egypt. C.L. Van Buskirk, R. Armitage, R. Stein

3:00 Intermission.

3:10 123. Plasma-Chemical Oxidation for AMS Radiocarbon Analysis of Plant Fiber Textile Yarns with Copper Carbonate Encrustations. I. Peterkin, B. Wilson, K. Jakes, R. Armitage

3:30 124. Comparing Combustion and Plasma-Chemical Oxidation Sample Preparation for AMS Radiocarbon Analysis of Known-age Materials. J. Bond, A. Bonneau, R. Armitage

3:50 125. Detection and Identification of Possible Tobacco Residues in Burnt Crusts on Hopewell Pottery from the Lower Illinois River Valley. C. Burnside, K. Farnsworth, C. Graves, G. Miller, R. Armitage

4:10 Closing remarks.