Embedded Files
Under review
Sung-A Kim†, Insoo Baik†, Yoon Ho Roh, Changyeon Lee, Jun Ki Ahn, Juhyuk Park, and Chang Yeol Lee*, "Amplification of CRISPR/Cas", submitted
2026
[50] Jieun Yang, Hyogu Han, Hyo Won Jeon, Chang Yeol Lee, Wooseok Yang, and Jun Ki Ahn "H1N1 Viral RNA Detection via FEN1-assisted Isothermal Amplification based on a Three-Way Junction" , Biochip Journal [IF = 6.1] [site]
[49] Goum Min, Jinsoo Na, Yugyeong Kang, Siheon Lee, Byounghyun Jeon, Hanjae Kim, Hyunjun Lee, Beomsoo Chun, Soojeong Yim, Jeonghun Kwak, Youngho Eom, and Chang Yeol Lee*, Soon Hyoung Hwang*, Juhyuk Park*, “Reconfigurable Nanogap SERS for Multiscale Molecular Sensing on Curved Surfaces”, small [IF=12.1] [pdf] [SI]
[48] Hyogu Han, Hyo Won Jeon, Jieun Yang, Chang Yeol Lee*, and Jun Ki Ahn*, “Label-free and isothermal multiplex detection of miRNAs using self-priming hairpin probes and light-up aptamer transcription”, Analytica Chimica Acta [IF=6.0] [pdf] [SI]
[47] Hyojeong Kim†, Dongchan Kim†, Hyogu Han, Changyeon Lee, Yoon Ho Roh, Tae-Su Han, Eun-Kyung Lim, Juhyuk Park, Jun Ki Ahn, Taejoon Kang*, Juyeon Jung*, and Chang Yeol Lee*, “On-site microRNA detection with ‘off-the-shelf’ glucose meter empowered by chimeric probe connecting CRISPR/Cas13a activation to kinases-driven glucose phosphorylation”, Biosensors and Bioelectronics [IF=10.5] [pdf] [SI]
[46] Dongchan Kim†, Hyojeong Kim†, Changyeon Lee, Juhyuk Park, Jun Ki Ahn*, and Chang Yeol Lee*, “Tandem Invasive Signal Amplification for Sensitive, Fluorescence Polarization-Based Terminal Transferase Activity Assay”, Biochip Journal [IF=6.1] [pdf] [SI]
[45] Sangjae Kim†, Siheon Lee†, Jinsoo Na, James Sangmin Choo, Junsang Doh, Jeong-Yun Sun, Chang Yeol Lee, and Juhyuk Park*, “Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels”, Advanced Functional Materials [IF=19] e26901 [pdf] [SI]
2025
2024
[43] Chang Yeol Lee†, Hyunho Kim†, Ismail Degani†, Hanna Lee, Angel Sandoval, Thomas Randall, Amy Ly, Cesar M. Castro*, and Hakho Lee*, “Empowering the on-site detection of nucleic acids by integrating CRISPR and digital signal processing”, Nature Communications [IF=15.7], 15, 6271 [pdf] [SI]
[42] Hyogu Han, Se Hee Jang, Jun Ki Ahn*, and Chang Yeol Lee*, “DNA repair-retarded isothermal CRISPR amplification for rapid, sensitive base excision repair enzyme assay”, Analytica Chimica Acta [IF=6], 1314, 342799 [pdf] [SI]
[41] Jae Hoon Jeung, Hyogu Han, Chang Yeol Lee*, and Jun Ki Ahn*, “One-pot, One-step, Label-free miRNA Detection Method Based on the Structural Transition of Dumbbell Probe”, Talanta [IF=6.1], 274, 125944 [pdf] [SI]
2023
[40] Jae Hoon Jeung, Hyogu Han, Chang Yeol Lee*, and Jun Ki Ahn*, “CRISPR/Cas12a Collateral Cleavage Activity for Sensitive 3’-5’ Exonuclease Assay”, Biosensors [IF=5.6], 13, 963 [pdf] [SI]
[39] Hyogu Han, Chihyun Park, Chang Yeol Lee*, and Jun Ki Ahn*, “Background-filtered telomerase activity assay with cyclic DNA cleavage amplification”, Nanoscale [IF=5.1], 15, 16669-16674 [pdf] [SI]
[38] Hyogu Han, Jae Hoon Jeung, Se Hee Jang, Chang Yeol Lee*, and Jun Ki Ahn*, “Peroxidase-Mimicking Activity of Nanoceria for Label-Free Colorimetric Assay for Exonuclease III Activity”, International Journal of Molecular Sciences [IF=4.9], 24, 12330 [pdf] [SI]
[37] Yoon Ho Roh†, Chang Yeol Lee†, Sujin Lee, Hyunho Kim, Amy Ly, Cesar M. Castro, Jinwoo Cheon, Jae-Hyun Lee, and Hakho Lee*, “CRISPR-enhanced hydrogel microparticles for multiplexed detection of nucleic acids”, Advanced Science [IF=14.1], 10, 2206872 [pdf] [SI]
2022
[36] Hyun-Kyung Woo, Young Kwan Cho, Chang Yeol Lee, Haeun Lee, Cesar M. Castro, and Hakho Lee*, “Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma”, Theranostics [IF=13.3], 12, 1988-1998 [pdf] [SI]
[35] Jayeon Song, Hansol Kim, Chang Yeol Lee, Junhyeok Yoon, Won Sang Yoo*, and Hyun Gyu Park*, “Identification of thyroid hormone/thyroid hormone receptor interaction based on aptamer-assisted protein-induced fluorescence enhancement”, Biosensors and Bioelectronics [IF=10.5], 191, 113444 [pdf] [SI]
2021
[34] Jayeon Song†, Chang Yeol Lee†, and Hyun Gyu Park*, “Ultrasensitive multiplexed miRNA detection based on a self-priming hairpin-triggered isothermal cascade reaction”, Chemical Communications [IF=4.2], 58, 2279-2282 [pdf] [SI]
[33] Chang Yeol Lee†, Ismail Degani†, Jiyong Cheong†, Ralph Weissleder, Jae-Hyun Lee, Jinwoo Cheon*, and Hakho Lee*, “Development of integrated systems for on-site infection detection”, Accounts of Chemical Research [IF=17.7], 54, 3991-4000 [pdf]
[32] Yong Ju, Jaemin Kim, Yeonkyung Park, Chang Yeol Lee, Kyungnam Kim, Ki Ho Hong, Hyukmin Lee, Dongeun Yong*, and Hyun Gyu Park*, “Rapid and accurate clinical testing for COVID-19 by nicking and extension chain reaction system-based amplification (NESBA)”, Biosensors and Bioelectronics [IF=10.5], 196, 113689 [pdf] [SI]
[31] Chang Yeol Lee†, Ismail Degani†, Jiyong Cheong, Jae-Hyun Lee, Hyun-Jung Choi*, Jinwoo Cheon*, and Hakho Lee*, “Fluorescence polarization system for rapid COVID-19 diagnosis”, Biosensors and Bioelectronics [IF=10.5], 178, 113049 [pdf] [SI]
2020
[30] Jiyong Cheong†, Hojeong Yu†, Chang Yeol Lee, Jung-uk Lee, Hyung-Jung Choi, Jae-Hyun Lee*, Hakho Lee*, and Jinwoo Cheon*, “Fast detection of SARS-CoV-2 RNA via the integration of plasmonic thermocycling and fluorescence detection in a portable device”, Nature Biomedical Engineering [IF=26.6], 4, 1159-1167 [pdf] [SI]
[29] Hyo Yong Kim†, Chang Yeol Lee†, Hansol Kim, Kisoo Park*, and Hyun Gyu Park*, “Portable glucose meter-utilized label-free and washing-free telomerase assay”, Analyst [IF=3.3], 145, 5578-5583 [pdf] [SI]
[28] Hyo Yong Kim, Jun Ki Ahn, Chang Yeol Lee, and Hyun Gyu Park*, “A hairpin probe-mediated isothermal amplification to detect target nucleic acid”, Analytica Chimica Acta [IF=6], 1114, 7-14 [pdf] [SI]
[27] Youna Kim†, Yeonkyung Park†, Chang Yeol Lee, and Hyun Gyu Park*, “Colorimetric Assay for Uracil DNA Glycosylase Activity Based on Toehold-Mediated Strand Displacement Circuit”, Biotechnology Journal [IF=3.1], 15, 1900420 [pdf] [SI]
2019
[26] Yujin Jung, Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Target-activated DNA polymerase activity for sensitive RNase H activity assay”, Biotechnology Journal [IF=3.1], 14, 1800645 (Highlighted as an outside front cover article) [pdf] [SI]
[25] Chang Yeol Lee, Hansol Kim, Ki Soo Park*, and Hyun Gyu Park*, “Nucleic acid-based fluorescent methods for the determination of DNA repair enzyme activities: A review”, Analytica Chimica Acta [IF=6], 1060, 30-44 [pdf] [SI]
[24] Yujin Jung, Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Sensitive and specific detection of proteins based on target-responsive DNA polymerase activity”, Analytica Chimica Acta [IF=6], 1059, 80-85 [pdf] [SI]
[23] Jun Ki Ahn†, Hyo Yong Kim†, Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Label-free and washing-free alkaline phosphatase assay using a personal glucose meter”, Journal of Biological Engineering [IF=6.5], 13, 51 [pdf] [SI]
[22] Chang Yeol Lee, Hansol Kim, Hyo Yong Kim, Ki Soo Park*, and Hyun Gyu Park*, “Fluorescent S1 nuclease assay utilizing exponential strand displacement amplification”, Analyst [IF=3.3], 144, 3364-3368 [pdf] [SI]
[21] Chang Yeol Lee, Hyowon Jang, Hansol Kim, Yujin Jung, Ki Soo Park*, and Hyun Gyu Park*, “Sensitive detection of DNA from Chlamydia trachomatis by using flap endonuclease-assisted amplification and graphene oxide-based fluorescence signaling”, Microchimica Acta [IF=5.3], 186, 330 [pdf] [SI]
[20] Hyowon Jang†, Chang Yeol Lee†, Seoyoung Lee, and Hyun Gyu Park*, “Flap endonuclease-initiated enzymatic repairing amplification for ultrasensitive detection of target nucleic acids”, Nanoscale [IF=5.1], 11, 3633-3638 [pdf] [SI]
[19] Bhagwan S. Batule, Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Polymerization-sensitive switch-on monomer for terminal transferase activity assay”, Artificial cells, Nanomedicine, and Biotechnology [IF=4.5], 47, 256-259 [pdf] [SI]
2018
[18] Hansol Kim, Chang Yeol Lee, Jayeon Song, Junhyeok Yoon, Ki Soo Park*, and Hyun Gyu Park*, “Protein-induced fluorescence enhancement for a simple and universal detection of protein/small molecule interactions”, RSC Advances [IF=4.6], 8, 33913-33917 [pdf] [SI]
[17] Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “A simple, sensitive, and label-free assay for alkaline phosphatase activity based on target-promoted exponential strand displacement amplification”, Sensors and Actuators B: Chemical [IF=7.7], 262, 1001-1005 [pdf] [SI]
[16] Chang Yeol Lee, Hyo Yong Kim, Soeun Kim, Ki Soo Park*, and Hyun Gyu Park*, “A simple and sensitive detection of small molecule-protein interaction based on terminal protection-mediated exponential strand displacement amplification”, Analyst [IF=3.3], 143, 2023-2028 [pdf] [SI]
[15] Jun Ki Ahn, Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Abasic site-assisted inhibition of nicking endonuclease activity for the sensitive determination of uracil DNA glycosylase”, Biotechnology Journal [IF=3.1], 13, 1700603 (2018.04.16) [pdf] [SI]
[14] Ye Lim Jung, Chang Yeol Lee, Jung Hun Park, Ki Soo Park*, and Hyun Gyu Park*, “A signal-on, colorimetric determination of deoxyribonuclease I activity utilizing photoinduced synthesis of gold nanoparticles”, Nanoscale [IF=5.1], 10, 4339-4343 [pdf] [SI]
[13] Yeonkyung Park, Chang Yeol Lee, Shinyoung Kang, Hansol Kim, Ki Soo Park*, and Hyun Gyu Park*, “Universal, colorimetric microRNA detection strategy based on target-catalyzed toehold-mediated strand displacement reaction”, Nanotechnology [IF=2.8], 29, 085501 [pdf] [SI]
[12] Kwan Woo Park†, Chang Yeol Lee†, Bhagwan S. Batule, Ki Soo Park*, and Hyun Gyu Park*, “Ultrasensitive DNA detection based on target-triggered rolling circle amplification and fluorescent poly (thymine)-templated copper nanoparticles”, RSC Advances [IF=4.3], 8, 1958-1962 [pdf] [SI]
2017
[11] Chang Yeol Lee, Ki Soo Park*, and Hyun Gyu Park*, “Pyrrolo-dC modified duplex DNA as a novel probe for the sensitive assay for base excision repair enzyme activity” Biosensors and Bioelectronics [IF=10.5], 98, 210-214 [pdf] [SI]
[10] Chang Yeol Lee, Kyoung Suk Kang, Ki Soo Park*, and Hyun Gyu Park*, “Determination of RNase H activity via real-time monitoring of target-triggered rolling circle amplification”, Microchimica Acta [IF=5.3], 185, 53 [pdf] [SI]
[9] Yeonkyung Park, Chang Yeol Lee, Ki Soo Park, and Hyun Gyu Park*, “Enzyme-free colorimetric detection of Cu2+ by utilizing target-triggered DNAzymes and toehold-mediated DNA strand displacement event”, Chemistry-A-European Journal [IF=3.7], 23, 17379-17383 [pdf] [SI]
[8] Chang Yeol Lee†, Hyowon Jang†, Ki Soo Park*, and Hyun Gyu Park*, “A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay”, Nanoscale [IF=5.1], 9, 16149-16153 (Highlighted as an outside front cover article) [pdf] [SI]
[7] Chang Yeol Lee, Hyo Yong Kim, Jun Ki Ahn, Ki Soo Park*, and Hyun Gyu Park*, “Rapid and label-free strategy for the sensitive detection of Hg2+ based on target-triggered exponential strand displacement amplification”, RSC Advances [IF=4.6], 7, 47143-47147 [pdf] [SI]
[6] Chang Yeol Lee, Ki Soo Park, Yun Kyung Jung, and Hyun Gyu Park*, “A label-free fluorescent assay for deoxyribonuclease I activity based on DNA-templated silver nanocluster/graphene oxide nanocomposite”, Biosensors and Bioelectronics [IF=10.5], 93, 293-297 [pdf] [SI]
[5] Ki Soo Park, Chang Yeol Lee, Kyoung Suk Kang, and Hyun Gyu Park*, “Aptamer-mediated universal enzyme assay based on target-triggered DNA polymerase activity” Biosensors and Bioelectronics [IF=10.5], 88, 48-54 [pdf] [SI]
2016
2015
[3] Chang Yeol Lee, Ki Soo Park, and Hyun Gyu Park*, “A fluorescent G-quadruplex probe for the assay of base excision repair enzyme activity”, Chemical Communications [IF=4.2], 51, 13744-13747 (Highlighted as a back cover article) [pdf] [SI]
[2] Ki Soo Park, Chang Yeol Lee, and Hyun Gyu Park*, “Target DNA-induced switches of DNA polymerase activity”, Chemical Communications [IF=4.2], 51, 9942-9945 [pdf] [SI]
2014
Page updated
Google Sites
Report abuse