2021
The purpose of this pilot study was to determine the ability of an infographic to improve the comprehension of hydration information of student athletes. Research has revealed that numerous athletes do not have the necessary sports nutrition knowledge, which puts the athletes at risk for making inaccurate and uninformed decisions. The sample for this study included student athletes at California State University, Los Angeles (Cal State LA). Four student athletes, one male and three females, between the ages of 18-21, completed a Qualtrics survey consisting of a hydration infographic and questions pertaining to that infographic. The data collected from this study has the potential to serve as a model for similar health education research with the goal to improve the understanding of sports nutrition among athletes and coaches.
Breast cancer is the leading cause of cancer related deaths in women. SKBR3 cell line is a human breast cancer cell line that overexpresses HER 2 gene product which has been involved in breast cancer proliferation pathways. Mouse studies modeling breast cancer have demonstrated the potent anticancer characteristics of tocotrienols, particularly gamma and delta tocotrienols. Gamma tocotrienols have been shown to lower breast cancer cell growth. Signaling pathways associated with promoting cell cycle progression, growth, and survival have been suppressed by tocotrienols. We hypothesize that δ tocotrienol will inhibit cancer cell growth by suppressing HMG- CoA reductase, the rate-limiting enzyme involved in the mevalonate pathway, and its subsequent metabolites Ras. We have designed our experiment where increasing dosages of δ tocotrienol (0μM – 50μM) are used to treat SKBR3 HER2+ breast cancer cells. δ-Tocotrienol (15 μM), significantly induced cell death as observed by a decrease in the number of DAPI stained cells and percent cell viability when compared to the control group. Western-blot analysis showed that δ-tocotrienol had no impact on RAS expression. Annexin V results show an increase in apoptosis after treatment.
2020
The purpose of this research was to give a group of trained swimmers two 3-day diets– one high carbohydrate, and low fat (HCLF) and the other low carbohydrate, and high fat (LCHF) in a randomized crossover design to determine swimming economy following each diet. Diets for each swimmer were personally tailored to individual food preferences using data from a 3-day food recall. Total caloric intake for each diet was calculated using energy expenditure prediction equations, and macronutrients followed the distribution of 70-15-15% and 15-70-15% carbohydrate-fat-protein for the HCLF and LCHF diets, respectively. After the swimmers followed the diets for three consecutive days, they swam in a swim flume at 50, 60 and 70% of their VO2max while their expired breath was collected and analyzed. It was found that RER was significantly higher in the HCLF diet compared to the LCHF diet. There were no significant differences found in heart rate, rate of oxygen consumption, or energetic cost between diet interventions. Although this study did not demonstrate improved economy at submaximal swimming speeds following short-term high and low carbohydrate diets, the current body of literature of cycling and running studies hold compelling evidence to suggest that further research is needed to determine if carbohydrate intake affects swimming economy.
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Add information about your project. You can include success metrics, timelines, and the latest updates. You can make a copy of the project page and link to it from here.