Monday March 25th, 2019

11h00: Marc Diederich, Mustapha Cherkaoui Malki, Claus Jacob:

Welcome address and dissemination activities

12h30: Lunch break

Session 1. Oxidative stress (Chairman: Marc Diederich)

14h00: Michael J. Davies (Dept. of Biomedical Sciences, Panum Institute, University of Copenhagen, Denmark): Quantification and mechanisms of oxidative stress in chronic disease

14h30: Mustapha Cherkaoui Malki (Laboratory BioPeroxIL, University of Bourgogne-Franche Comté, Dijon, France): Cytoprotective and antioxidants in peroxisomal neurodegenerative diseases

15h00: Andriy P. Cherkas (Lviv National Medical University/Sanofi-Aventis Deutschland GmbH): Helicobacter pylori in health and disease: its contribution to gastrointestinal disorders and systemic metabolic effects

Session 2. Epigenetic alterations (Chairman: Mustapha Cherkaoui Malki)

15h15: Michael Schnekenburger (LBMCC, Luxemburg): Natural compounds as epigenetic modulators in cancer

15h45: Wim Vanden Berghe (PPES Epigenetic Signaling, Wilrijk (Antwerpen), Beligum): Blood surrogate epigenetic biomarkers of atherosclerosis reveal common signature of inflammaging-disorders

16h15: Carsten Carlberg (University of Eastern Finland, Kuopio, Finland): Epigenome-wide effects of vitamin D

16h45: Patrycja Jakubek (Faculty of Chemistry, Gdańsk University of Technology, Poland): DNA methylation changes induced by redox-active compounds – choosing the right PCR-based method

17h00: Coffee break & Posters

Session 3. Metabolic alterations (Chairman: Claus Jacob)

17h30: Shlomo Sasson (Institute for Drug Research, Faculty of Medicine, The Hebrew University, Jerusalem Israel): Fatty Aldehyde Dehydrogenase (ALDH3A2)-dependent neutralization of Advanced Lipid Peroxidation End Products (ALEs) at the bifurcation of hormetic and degenerative pathways in pancreatic beta cells

18h00: Lars-Oliver Klotz (Inst Nutritional Sciences, University of Jena, Germany): FOXO transcription factors: regulators of metabolism and stress resistance

18h30: Niki Chondrogianni (Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece): Quest for anti-ageing compounds in our diet: potential anti-ageing and anti-aggregation applications

19h00: End of the scientific day