Changes in the human gut microbiome has been shown to be associated with altered human metabolism and health, yet the mechanisms of interactions between microbial species and human metabolism have not been clearly elucidated. Therefore, our aim is to explore the metabolism, and metabolic interactions in experimental populations and human cohort leveraging both engineering and evolutionary principles. We think that linking metabolic activities holds the key to deciphering the biological roles of gut microorganisms and unlocking their therapeutic potential.

Our projects in human gut microbiome focused on:

• The metabolic capabilities of human gut microorganisms
  See our recent work related to CAZYme, Bile acid et.al.

• The microbial interactions and host-microbe interaction.
  See our recent work related to co-culture, malnutrition et.al.

• Modelling the dynamics of microbial communities in human health and disease
  See our recent work related to modelling, malnutrition et.al.

• Design of artificial microbiota with targeted functions
  Ongoing