Publications

Publications (Independent Career) 

• K. Texidor, D. Uyghur, N. Wiese, L.O. Davis, M. Green, F. Sharmen, A. Ijaz, K.M. Barnes, M. Bagett, J. Ye, S.M. Abbang, W. Piao, J.Y.K. Chan, Y.K. Ng, V.W.Y. Lui, M. Orecchioni, M. Borgini*. Synthesis and characterization of bicyclo[1.1.0]butane amides and 5-methylene-3-azabicyclo[5.1.0]octan-4-ones as covalent modifiers. Bioorg Med Chem Lett. 2026, 135, 130572. Link

• E.G. Ayala-Cosme, D. Yang, K. Vences, L.O. Davis, M. Borgini*. State-of-the-Art Nrf2 Inhibitors: Therapeutic Opportunities in Non-Cancer Diseases. ChemMedChem, 2024, e202400377. Link

Publications (Mentored Research)  

• A.P. Welegedara, Y. J. Tan, M. Borgini, P. Wipf, G. Otting. 19F-NMR spectroscopy of fluorinated isoleucine analogues in a protein. J Biomol NMR, 2026, 80, 7. Link

• M. Borgini, Q. Huang, P. Chen, S.J. Geib, K.N. Houk, P. Wipf Rhodium(I)-Catalyzed Annulation of Bicyclo[1.1.0]butyl-Substituted Dihydroquinolines and Dihydropyridines. JACS, 2024, 146(22), 14927-14934. Link  Highlighted on Synfacts (Synfacts 2024, 20(08), 0824). Link

• M. Borgini, Ł. Wieteska, C.S. Hinck, T. Krzysiak, A.P. Hinck, P. Wipf. Synthesis of 13C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells. Org. Biomol Chem. 2023, 21(46), 9216-9229. Link

• M. Borgini, P. Wipf. Synthesis of Veliparib Prodrugs and Determination of Drug-Release-Dependent PARP-1 Inhibition, ACS Medicinal Chemistry Letters, 2023, 14(5), 652-657. Link

• M. Borgini, P. Wipf. Stereoselective synthesis of δ-fluorinated isoleucines exploiting consecutive C(sp3)-H bond activations, Tetrahedron, 2022, 120, 132876. Special issue in Honor of Dr. Franziska Schoenebeck. Link

• M. Borgini, P. Mondal, R. Liu, P. Wipf. Chemical modulation of Kv7 potassium channels, RSC Medicinal Chemistry, 2021, 12, 483-537. Link

• M. Borgini, C. Zamperini, F. Poggialini, L. Ferrante, V. Summa, M. Botta, R. Di Fabio. Synthesis and Antiproliferative Activity of Nitric Oxide-Donor Largazole Prodrugs, ACS Medicinal Chemistry Letters, 2020, 11(5), 846-851. Link

• F. Orofino, G. I. Truglio, D. Fiorucci, I. D'Agostino, M. Borgini, F. Poggialini, C. Zamperini, E. Dreassi, L. Maccari, R. Torelli, C. Martini, M. Bernabei, J. F. Meis, N. K. Khandelwal, R. Prasad, M. Sanguinetti, F. Bugli, M. Botta. In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains, International Journal of Antimicrobial Agents, 2020, 55(3), 105865. Link

• M. Borgini, F. Orofino, G. I. Truglio, L. Balestri, M. Botta. A gram-scale synthesis of a macrocyclic amidinourea with strong antifungal activity through a Fukuyama tri-protected polyamine intermediate, Arkivoc, 2019, 4, 168- 177. Special issue in Honor of Dr. Stephen Hanessian. Link

• Brai, S. Ronzini, V. Riva, L. Botta, C. Zamperini, M. Borgini, C. I. Trivisani, A. Garbelli, C. Pennisi, A. Boccuto, F. Saladini, M. Zazzi, Maga, M. Botta. Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X, Molecules, 2019, 24(21), 3988. Link