Welcome to Menon Lab @ Portsmouth
We are developing several synthetic biology based biosynthetic pathways for the sustainable and bio-renewable preparation of chemicals and value added molecules. Our aim is to utilise specific regio- and stereo-selective enzymatic reactions to create new pathways and biocatalytic cascades in microorganisms, that could basically convert sugar and carbon sources into industrially valuable compounds. We target biopharmaceuticals, natural products, biopolymers and biofuels in our specialised Synthetic Biology approaches. This involves metabolic and chassis engineering in microorganisms, biocatalyst and pathway engineering, and integration with other areas of expertise such as computational and experimental biology, analytical sciences, automation/robotics and high-throughput assay developments.
Cummings, Matthew, Peters, Anna D., Whitehead, George F.S., Menon, Binuraj R.K., Micklefield, Jason, Webb, Simon J., Takano, Eriko. 2019. Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli. PLOS Biology, View
Menon, Navya, Pásztor, András, Menon, Binuraj R. K., Kallio, Pauli, Fisher, Karl, Akhtar, M. Kalim, Leys, David, Jones, Patrik R., Scrutton, Nigel S.. 2015. A microbial platform for renewable propane synthesis based on a fermentative butanol pathway. Biotechnology for Biofuels, 8 (1), View