Bioelectricity

AE effects comes from an interaction between electrical current and acoustic pressure generated when acoustic waves travel through a conducting material. It currently has two main application areas, ultrasound current source density imaging (UCSDI) and AE hydrophone.

UCSDI can detect the current direction by modulating the dipole field with ultrasound pulse, and it is now used to form 4-D imaging of dipole changing in one period of treatment, such as arrhythmia in the heart and epilepsy in the brain. As ultrasound pulse passes through electrical field, it convolutes with the inner product of the electric fields formed by the dipole and detector. As convolution shifts spectrum lower, the base band frequency for polarity is different from the center frequency of AE signal. The simulation uses the principles of UCSDI, and helps to understand the phenomena in the experiment of a time-varying dipole field.

1. Zhaohui Wang, Rajab Challoo, Hu Peng, Chung S. Leung, and Russell S. Witte, “Complementary detection of multiple electrical sources in tissue using acoustoelectric effect,” Ultrasound in Medicine and Biology, vol. 42, no. 9, pp. 2323-2333, 2016.

2. Zhaohui Wang, Wei-Da Hao, Chung S. Leung, Sung-won Park, “Polarity detection in ultrasound current source density imaging,” in Proc. Annu. Int. IEEE-EMBS Conf., vol. 38, pp.1095-1098, 2016.

3. Zhaohui Wang, Russell S. Witte, “Simulation Based Validation for Four Dimensional Multi-Channel Ultrasound Current Source Density Imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 61(3), 420-427 (2014).

4. Yexian Qin, Zhaohui Wang, Pier Ingram, Qian Li, Russell Witte, “Optimizing frequency and pulse shape for ultrasound current source density imaging,” IEEE Trans. on Ultrasonics, Ferroelectrics and Frequency Control 60(9), 1906-1916 (2013).

5. Qian Li, Ragnar Olafsson, Pier Ingram, Zhaohui Wang and Russell Witte, “Measuring the acoustoelectric interaction constant using ultrasound current source density imaging,” Phys. Med. Biol. 57 , 5929-5941 (2012).

6. Zhaohui Wang, Ragnar Olafsson, Pier Ingram, Qian Li, Yexian Yin, Russell S. Witte. “Four-dimensional ultrasound current source density imaging of a dipole field,” Applied Physics Letters 99, 113701 (2011).

7. Zhaohui Wang, Pier Ingram, Ragnar Olafsson, Qian Li, R.S. Witte, “Detection of multiple electrical sources in tissue using ultrasound current source density imaging,” Proceedings of SPIE 7629, 76290H (2010).

8. Zhaohui Wang, Ragnar Olafsson, Pier Ingram, Qian Li, Russell S. Witte, ''Multichannel ultrasound current source density imaging of a 3-D dipole field,'' 2010 IEEE Ultrasonics Symposium Proceedings, 253-256 (2010).

9. Zhaohui Wang, Pier Ingram, Ragnar Olafsson, Qian Li, R.S. Witte, ''Detection of multiple electrical sources in tissue using ultrasound current source density imaging,'' Proceedings of SPIE 7629, 76290H (2010).