Publications

1. Fortunato, M. A. G., Siopa, F. & Afonso, C. A. M. (1r,4s,5s)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1htetrazol-5-yl)thio)cyclopent-2-en-1-ol. MolBank 2021, (2021).

2. Gomes, R. F. A., Isca, V. M. S., Andrade, K., Rijo, P. & Afonso, C. A. M. Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents. ChemMedChem 16, 2781–2785 (2021).

3. Ravutsov, M. et al. Co2 adsorption on modified mesoporous silicas: The role of the adsorption sites. Nanomaterials 11, (2021).

4. Ravasco, J. M. J. M. & Gomes, R. F. A. Recent Advances on Diels-Alder-Driven Preparation of Bio-Based Aromatics. ChemSusChem 14, 3047–3053 (2021).

5. Gomes, R. F. A. et al. Silica-Supported Copper for the Preparation of trans-4,5-Diamino-Cyclopent-2-Enones under Continuous Flow Conditions. ACS Sustainable Chemistry and Engineering 9, 16038–16043 (2021).

6. Kamenova, K. et al. Functional Nanogel from Natural Substances for Delivery of Doxorubicin †. Polymers 14, (2022).

7. Rosatella, A. A. & Afonso, C. A. M. One-Pot Transformation of Salicylaldehydes to Spiroepoxydienones via the Adler-Becker Reaction in a Continuous Flow. ACS Omega 7, 11570–11577 (2022).

8. Rafael, R. F. et al. Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived δ-Lactone-Fused Cyclopentenones. ChemSusChem 15, (2022).

9. Fernández-Figueiras, A., Ravutsov, M. A. & Simeonov, S. P. Site-Selective C−H Functionalization of Arenes Enabled by Noncovalent Interactions. ACS Omega vol. 7 6439–6448 (2022).

10. Cavaca, L. A. S. et al. Upgrading furanic platforms to α-enaminones: tunable continuous flow hydrogenation of bio-based cyclopentenones. Reaction Chemistry and Engineering 8, 482–489 (2022).

11. Cavaca, L. A. S., Gomes, R. F. A. & Afonso, C. A. M. Preparation of Thioaminals in Water. Molecules 27, (2022).

12. Pereira, J. G., Ravasco, J. M. J. M., Vale, J. R., Queda, F. & Gomes, R. F. A. A direct Diels-Alder reaction of chitin derived 3-acetamido-5-acetylfuran. Green Chemistry 24, 7131–7136 (2022).

13. Curpanen, S. et al. Modular synthesis of 2-furyl carbinols from 3-benzyl-dimethylsilylfurfural platforms relying on oxygen-assisted C–Si bond functionalization. Beilstein Journal of Organic Chemistry 18, 1256–1263 (2022).

14. Slavchev, I., Ward, J. S., Rissanen, K., Dobrikov, G. M. & Simeonov, S. Base-promoted direct amidation of esters: beyond the current scope and practical applications. RSC Advances 12, 20555–20562 (2022).

15. Ciriani, M., Oliveira, R. & Afonso, C. A. M. Semi-continuous and continuous processes for enantiomeric separation. Green Chemistry vol. 24 4328–4362 (2022).

16. Grancharov, G. et al. Biorenewable Oxypropylated Pentane-1,2,5-triol as a Source for Incorporation in Rigid Polyurethane Foams. Polymers 15, (2023).

17. Gomes, R. F. A., Vale, J. R., Pereira, J. G. & Afonso, C. A. M. Orthogonally Protected Diaminocyclopentenones as Synthons: Total Synthesis of (±)-Agelastatin A. Organic Letters 25, 4188–4192 (2023).

18. Gomes, R. F. A. & Afonso, C. A. M. Preparation of Aminals under Continuous Flow Conditions. Journal of Chemical Education 100, 4728–4733 (2023).

19. Gomes, R. F. A. et al. Unlocking the Potential of Bio-Based Nitrogen-Rich Furanic Platforms as Biomass Synthons. Angewandte Chemie - International Edition 62, (2023).

20. Dangalov, M. et al. Ru-Catalyzed Isomerization of Achmatowicz Derivatives: A Sustainable Route to Biorenewables and Bioactive Lactones. ACS Catalysis 13, 1916–1925 (2023).

21. Petkov, H. & Simeonov, S. P. Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches. Applied Sciences (Switzerland) vol. 13 (2023).

22. Kinkutu, G. K., Louis, C., Roy, M., Blanchard, J. & Oble, J. C3-Alkylation of furfural derivatives by continuous flow homogeneous catalysis. Beilstein Journal of Organic Chemistry 19, 582–592 (2023).

23. Andrade, K. H. S. et al. Functionalized Cyclopentenones with Low Electrophilic Character as Anticancer Agents. ChemMedChem 18, (2023).

24. Vale, J. R. et al. From Pyridine to (−)-Agelastatin A. Advanced Synthesis and Catalysis 365, 2240–2247 (2023).

25. Petkov, H. et al. Cu-Catalyzed Tandem Oxidation-Intramolecular Cannizzaro Reaction of Biorenewables and Bioactive Molecules. ChemSusChem 17, (2024).

26. Bossons, N. & Gomes, R. F. A. Sustainable synthesis of nitrogen-rich aromatics from chitin: Opportunities and challenges. Current Opinion in Green and Sustainable Chemistry vol. 49 (2024).

27. Durão, R. M., Marinova, M. K., Ravutsov, M. A. & Simeonov, S. P. 4-Ketovalero lactone (KVL): A gateway molecule for diversification of the furanic platform. Sustainable Chemistry and Pharmacy 39, (2024).

28. Ravutsov, M. A., Marinova, M. M., Kurutos, A. & Simeonov, S. P. Sources, sustainability and directions in the chemical synthesis of δ-aminolevulinic acid. Sustainable Chemistry and Pharmacy vol. 38 (2024).

29. Cavaca, L. A. S., Santos, T. M. P., Ravasco, J. M. J. M., Gomes, R. F. A. & Afonso, C. A. M. High-Pressure Promoted Nazarov-like Electrocyclization Enables Access to trans-4,5-Diamino-cyclopent-2-enones Bearing Electron-Poor Anilines. Journal of Organic Chemistry 89, 6677–6683 (2024).

30. Bento, C., Katz, M., Santos, M. M. M. & Afonso, C. A. M. Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol. Organic Process Research and Development vol. 28 860–890 (2024).

31. Crespo Monteiro, M., Vale, J. R. & Siopa, F. 2-Azabicyclo[3.2.1]octane scaffold: synthesis and applications. Organic and Biomolecular Chemistry vol. 22 2902–2915 (2024).