Research Associate (Postdoctoral Fellow)
Hello, I am Dr. Tanusree Saha, a Research Associate at the Bio-INvENT Lab since April 2024. I received my Bachelor’s and Master’s degrees in Microbiology followed by my PhD in Biochemistry from the University of Calcutta, India in 2017. My graduate research focused on the correlation of folate metabolic system polymorphism with Attention Deficit Hyperactivity Disorder. After my doctoral degree, I was awarded of SERB-national postdoctoral fellowship in 2018 on retromer-mediated regulation of Cu-ATPases and pursued my research at IISER-Kolkata, India. In the year 2019, I moved to the USA for further postdoctoral study at the University of Kentucky and the University of Alabama at Birmingham respectively.
Currently, I am working on a DBT Funded Project titled "Network Center for research on glioblastoma stem cell–targeted T-cell immunotherapy using non-genetically engineered mesenchymal stromal cells.“
My current research focuses on the isolation and characterization of gamma delta T cells and GSCs from primary glioblastoma patients with a strong interest in studying the crosstalk among GSC, MSC, and T cells in Glioblastoma. Apart from my scientific endeavors, I love reading novels, painting, gardening, cooking, and traveling.
PhD Students
Rudraradhya U
This is Rudraradhya! I did my Master’s in Biochemistry at Davanagere University. During my master's, I did a project on the Neurobiology of Learning and Memory formation. I started my career as a Research Assistant in Genotoxicity at Liveon Biolabs Pvt. Ltd. Hence, I started the ‘Soil Health Care Lab’ under the NMSA project funded by 5 Lacks from both Govt. of India and the state government.
I joined Bio-INvENT Lab as a PhD student in 2024. My research work is on “Prophylactic drug delivery to the donor corneal endothelium to enhance the success of corneal transplantation”. My areas of expertise include Mammalian cell culture, cell and molecular biology, laboratory animal handling and dosing, and Genotoxicity assays (CAT, MLA, MTT).
I’m currently learning nanoparticle preparation and drug delivery systems for the treatment of corneal disorders, during storage and after transplantation. I am also inclined towards Entrepreneurship.
When you don’t see me in the lab, you can find me in the campus gym
Namaste, I’m Varsha G, a PhD research scholar at Siddaganga Institute of Technology since March 2024 under the guidance of Dr. H S Lalithamba, Department of Chemistry, SIT, and under the co-guidance of Dr. Sudhir H Ranganath, Department of Chemical Engineering, SIT. I hold a Master's Degree in Chemistry from REVA University, Bengaluru. Currently, I am involved in a Project titled “Synthesis and development of injectable, intravitreal, and stimuli-responsive drug delivery system to treat eye diseases.”
The research involves the development of a thermo-and light-responsive drug delivery system for the eye disease Uveitis and a thermo-and enzyme-responsive drug delivery system for the eye disease Fungal Endophthalmitis.
In addition to my academic pursuits, I’ve industrial working experience of one year in an MNC “Bureau Veritas”, Bengaluru where I have hands-on training in UV Spectrophotometer, HPLC, and LCMS. Also, I have teaching experience from an Engineering college, HMSIT, Tumakuru.
Beyond my scientific endeavors, I harbor a deep passion for music, with singing being a cherished form of expression for me.
Junior Research Fellow
Kavya S U
Hello, I'm Kavya, a Junior Research Fellow at the Bio-INvENT Lab since February 2024. I hold a Master's Degree in Microbiology from Tumkur University. Currently, I am immersed in a DBT DBT-funded project titled "Network Center for research on glioblastoma stem cell–targeted T-cell immunotherapy using non-genetically engineered mesenchymal stromal cells."
My primary research revolves around Mesenchymal Stem Cells (MSCs), particularly in engineering their cell membrane with CD133-specific aptamers/peptides. This modification aims to induce CD133-specific binding, allowing us to explore their migration across endothelial cell layers and their affinity towards specific CD133+ Glioblastoma Stem Cells (GSCs).
In addition to my academic pursuits, I've achieved success in competitive exams. I cleared the Graduate Aptitude Test in Engineering (GATE) in both 2023 and 2024. Furthermore, I qualified for the CSIR NET Assistant Professorship in Life Sciences in 2023.
Beyond my scientific endeavors, I'm an avid reader, particularly drawn to literature, especially novels. Additionally, I harbor a deep passion for music, with singing being a cherished form of expression for me.
Project Manager
Hey everyone, it's Anjana here ̶ your friendly neighborhood Project Manager at Bio-INvENT lab.
Let me give you the lowdown on what I do: I'm the one keeping our projects financially sound while ensuring our lab runs like a well-oiled machine. Exactly how it needs to be.
You see, I'm not just your average numbers person. I've got history with this lab - graduated from the same college, and did my projects right here. Having walked the halls of this lab during my college days and then ventured into the industry jungle for a couple of years at Bioneeds, I can safely say there's no place like home. So, when Bio-INvENT came calling, I knew I had to answer.
When I'm not crunching numbers or chasing down funding, you'll probably find me lost in a good book, binge-watching the latest series, or shamelessly scrolling through Instagram. Hey, a girl's gotta have her hobbies, right?
But let's get back to business. I'm here to make sure our lab thrives, and with your support, I know we'll do just that. So here's to us - the Bio-INvENT family - making waves in the world of science, one budget at a time.
Catch you in the lab!
Master's students
Hello!! I am Appurva. Presently, I'm engaged in pursuing an M.S. (Research) program in chemical engineering, starting in 2022, following my completion of a Bachelor of Engineering (B.E.) degree in Chemical Engineering in 2018 from Siddaganga Institute of Technology.
My ongoing research is centered on the development of a methodology aimed at extracting lithium from RO reject water utilizing cutting-edge Deep Eutectic Solvent technology as it poses a significant ecological hazard due to its elevated salinity upon reintegration into marine environments. The extraction of valuable metals such as Li, Co, and Ni from RO reject water, represents an underexplored domain necessitating investigation through eco-friendly avenues.
The objectives of my research are to examine various Deep Eutectic Solvents (DESs) blends for compatibility with RO reject water and lithium solubility, and then assess their effectiveness in lithium extraction. Adjust different process parameters to recover lithium from DES in a usable salt form using separation techniques.
I received the Karnataka State Council for Science and Technology (KSCST) Student Grant (Rs. 8000/-) in Jan 2018 and the Indian Institute of Chemical Engineers (IIChE) Project Grant (Rs. 5000/-) for significant projects., Presented a paper on "Mitocurcumin functionalized carbon dots for Theranostic applications" at REFLUX-2018, IIT, Guwahati, and showcased a poster at SYNERGY 2018 in Sankara Nethralaya, Chennai.
Research Intern
Hi, I am Chaitra. I have completed an M.Sc. In biotechnology having six years of experience in the teaching field, I trained students with a diverse range of abilities and successfully guided them to accomplish their goals.
I joined in August 2023 as an intern at Bio-INvENT Lab to pursue my career with long-term goals. As a member of the Corneal Dystrophy team, I have had an opportunity to enhance my knowledge regarding Corneal diseases and delivered a few presentations on the anatomy and physiology of the Cornea, Fuchs endothelial corneal dystrophy, oxidative stress related to FECD, and the disease which is associated to FECD Pseudophakic bullous keratopathy.
I received a certificate of participation from Nethrakalpa – 2024 organized by the Tumkur Ophthalmic Society in February 2024 at Shridevi Institute of Medical Sciences and Research Hospital Tumakuru.
Currently, I am preparing to write a research proposal for the Department of Science and Technology WISE women fellowship for PhD 2024
Undergraduate Students
Meet Team Cornea!!! We're a diverse squad of Chemical Engineering and Biotechnology undergrads from SIT. We joined the Bio-INvENT lab as undergraduate research interns in 2021. Since then we have taken on the challenge of addressing hypothermia in corneal endothelium using fusogenic liposome coated nanoparticles. Additionally, we're evaluating the cytotoxicity of PLGA nanoparticles in corneal endothelium while optimizing the parameters for their production yield and exploring strategies for the long-term retention of fusogenic liposome-coated nanoparticles in the donor corneal endothelium. We are also investigating the role of ferroptosis and its downstream effects in the corneal endothelial cells.
More about us:
Suraj K S: I'm a final-year Chemical Engineering student at SIT. Fascinated by the interdisciplinary nature of Chemical Engineering in addressing modern-day challenges, I joined the lab as a freshman in 2021 to contribute to the field of biomaterials and drug delivery. The lab has been an exceptional arena for both personal and academic growth. This intense lab experience significantly honed my research skills, leading to a research internship at IIT-Hyderabad. Additionally, I have secured a runner-up position in the poster presentation at the PRIME International Summit held at Narayana Netralaya. Outside academics, I’m an impromptu tripper, an avid tennis fan, and love exploring new cuisines as a hardcore foodie.
Namratha Ganiga: Research has been my passion since high school, where I developed a keen interest in exploring scientific investigations. This passion led me to the Bio Invent Lab, where I explored the fascinating world of corneal research where I studied many more things like drug delivery, Nanoparticle cytotoxicity, iron-induced cell death in corneal endothelium, etc. It’s been a journey of discovery, and I’m excited to see where it leads! I’m also the recipient of the Sigma XI grant 2024 for vision research from Sigma Xi, USA. My other interests are journaling, dancing, and reading books.
Deepika T G: Hi there, I am Deepika, a chemical engineering student with a passion for science and its art. I like to explore biomedical science as a chemical engineer, and its various applications. I have done my research work on nanoparticles where my team researched nanoparticle-based drug delivery for corneal transplantation success. Developed fusogenic liposome-coated nanoparticles for efficient delivery into corneal endothelial cells, protecting against cold and cytokine stress. Proposed strategy to target allograft rejection, stabilize microtubules, preserve barrier integrity, and optimize various parameters to enhance the yield of nanoparticles. I have received second place in the Chemplus oral presentation held at IIT Madras. I believe that whatever work you start with put your 100% effort into it and make sure you work honestly and ethically.
B M Meghashree: Heya!! I’m B M Meghashree pursuing my BE in biotechnology at SIT. I’m grateful to be a part of the Bio-INvENT Lab. I joined the lab when it was the summer gap. I have learned and gained knowledge on the concepts related to corneal stress induced how to tackle that and many more chemical engineering concepts too.
Priya S N: I, an undergrad B.E Biotechnology student who is always excited to be dynamic and looking forward to learning something new, led my path to the Bio-INvENT Research Lab as a new team member. I first started as an intern during the summer break after my 2nd year. I look forward to contributing to a groundbreaking project "Investigation of ferroptosis as the mechanism of hypothermia-induced cell death and barrier dysfunction in cold stored ex-vivo corneal endothelium" and collaborating with a team of esteemed members. Together, we aim to make significant strides in developing new therapeutic solutions.
Being a professional classical dancer, I also like traveling to different places and trying out the food there.
Vedashree C K: Hi there! I'm an undergraduate in Biotechnology Engineering. I joined Bio-INvENT Lab in 2022, for academic fulfillment I completed my internship here in the year 2023 and it had been a great time gaining knowledge along with hands-on experiences.
Currently, I am working on a project investigating ferroptosis as the mechanism of hypothermia-induced cell death and barrier dysfunction in cold-stored ex vivo corneal endothelium.
Bio-INvENT Lab has always been an open opportunity for young buds like us seeking exposure in the field of research and development. I am very grateful for the opportunity to be part of the lab and look forward to contributing to our shared success.
To tell you a little more about me, I am a bit silent but give occasional bursts of productive procrastination. Beyond my academic pursuits, my hobbies include swimming, playing chess, and going on nature walks and adventures. I am eager to contribute and create a meaningful impact. Reach out, and let's make a difference.
We are Team Lithium. Our team is dedicated to the extraction of lithium from both solid and liquid sources. We joined Bio-INvENT Lab as undergraduate research interns in 2022. Since then, we have been working to create effective and sustainable ways to recover lithium. Our efforts have taken us from creating an adsorbent to recover lithium from liquid ores to figuring out how to effectively recover lithium from Li-ion batteries. We are also exploring sustainable recovery methods such as Deep Eutectic Solvents (DESs).
More about us:
Deekshith R: I Joined as a research intern to work on Lithium-ion batteries and the project is in collaboration with Tvastra Innotech Solutions. Bio-INvENT Lab has provided me an opportunity to apply chemical engineering principles in the research as well as to explore the domain of energy storage materials. Having witnessed their transformative impact on technology, I'm dedicated to working in this exciting field with the potential to revolutionize how we power our future.
I am happy to share that I was a recipient of Best Project Award in SChemCON-2023 and also IIChE-BRC Grant for extraction of lithium via Lithium-ion sieve technique. I like to play football and do canvas paintings.
Madeeha Shah: Since I started studying chemical engineering, I've become increasingly fascinated by and amazed by how things function. The scientific world has always captivated me, and I want to understand how things are created. Bio-INvENT Lab offered me a space where I could bring my imagination to life, as well as everything I needed to make my ideas a reality. Not only that, but it also taught me the value of safety and other things I didn't know before. Well, we're never too old to keep learning, right?
Shrihari M S: Hey! I am currently pursuing a bachelor's in Chemical Engineering. I started my journey as a freshman intern in August 2022 with a vision to learn and channel my scientific curiosity at the Bio-INvENT Lab, under the guidance of inspiring Dr. Sudhir.
My work focuses on a separation technique 'Application of Deep Eutectic Solvents (DESs) for the extraction and recovery of Lithium from low-concentration sources', potentially developing novel and sustainable techniques for future energy demands.
I was a recipient of the KITE Internship-2022 sponsored by the Ministry of Heavy Industries, GOI at IIT Madras, and also a Summer Internship at the Indian Institute of Science. Along with my scientific studies, my hobbies include hiking, volunteering, and reading non-fiction books.
Meet Team PAW…..!! A squad that leads the Plasma Activated Water Nanoliposome Delivery. We are pioneering a drug-free approach to cancer treatment by utilizing cold atmospheric plasma (CAP) to create potent plasma-activated water (PAW). We focus on developing and optimizing nanoliposomes – microscopic carriers – to efficiently encapsulate and deliver plasma-activated water (PAW) directly to cancer cells. PAW, generated using cold atmospheric plasma technology, holds promise as a weapon against cancer due to its targeted action on these cells. This targeted approach aims to minimize side effects on healthy tissue, offering a potentially more effective and innovative weapon against cancer.
More about us:
Karthik R P Banakar: I am Karthik R.P. Banakar, a final-year Chemical Engineering student. My fascination with science and the intricate workings of nature blossomed into a passion for unraveling biological mysteries. This, coupled with his interest in biology, led him down the path of biomedical applications. An internship in the Bio-INvENT lab created an opportunity that served as a catalyst, igniting my initial intrigue into a burning desire to delve deeper. The stimulating lab environment provided the perfect breeding ground for my research drive to flourish. My dedication and insightful work haven't gone unnoticed.
I have actively presented my research at prestigious conferences, both Nationally and Internationally, and was even awarded the coveted "Best Paper Award" at SChemCON-2024. Beyond academics, travel beckons, igniting my desire to explore the natural world and immerse myself in the diverse cultures and cuisines our planet offers.
Namitha: I'm thrilled to be part of the Bio-INvENT Lab! I joined as a research intern to work on developing delivery systems for PAW to target cancer cells. Biology has always been my favorite and most fascinating subject to learn and explore. Now, being involved in a biomedical research project focused on controlled drug delivery, I have the opportunity to deepen my knowledge and understanding of this field. I also enjoy singing and sketching.
More about us:
Indira K G: Hii there! I am Indira K G, pursuing a B.E. in biotechnology. I'm deeply passionate about biomedical research because I believe in using science to do wonders. Working at Bio-INvENT Lab is an incredible opportunity, and I'm so thankful for the chance to be part of a team that's making such important discoveries in medicine.
I am currently immersed in a project at Bio-invent Lab titled 'Investigation of the effect of PAW (Plasma activated water) on liposome peroxidation: Implications for loading and delivery of PAW.' In this study, we aim to elucidate the influence of PAW on the oxidative stability of liposomes, a critical determinant of their capacity to encapsulate therapeutic agents and facilitate their targeted delivery to cancer cells. This investigation holds promise for advancing our understanding of liposomal drug delivery mechanisms, potentially paving the way for the development of more efficacious cancer therapeutics.
Sharanya D: I am Sharanya, a final-year biotechnology student who joined Bio-INvENT as a summer intern in 2022. Currently, pursuing research focused on the development of nanotechnology-based therapies for targeted drug delivery. Our work aims to enhance the efficacy and safety of PAW loaded in nanoliposomes. All these 3-year journeys in the Bio-INvENT lab exposed us to cutting-edge research projects and also had an opportunity as a research intern at IIT Hyderabad where we explored Microfluidics for the encapsulation of drugs inside nanoliposomes
Shraavya R: Hi there, I am Shraavya Shashidhar, a biotechnology student with a keen interest in cell and molecular biology. I am particularly fascinated by the complexities of genetics and genomics, with a special focus on understanding cancer cell mechanisms.
In my second year, I had the opportunity to engage in a 45-day lab project under the mentorship of Professor Dr. Sudhir H. Ranganath and senior researchers. During this time, I was trained in the application of Plasma Activated Water (PAW) using liposomes for cancer treatment and learned mammalian cell culture techniques. This project also exposed me to the process of reading and analyzing research papers. Motivated by this experience, I continued this project as both my mini and major project. I am committed to carrying this spirit and enthusiasm into my future research endeavors, seeking to gain further practical experience, knowledge, and skills.
Manaswini N Kiran: Hey! My interest has always been to work in the field of nanotechnology and the treatment of cancer. I joined Bio-INvENT lab in the year 2022 and that has been the stepping stone in improving my knowledge. My interest also lies in theatre, painting, and sports.
Ramya R: Hi everyone. I have always been curious about how technology is harnessed to solve biological challenges. Hence I found the lab, a great forum for me to gain experience.
Greetings, we are part of Team Glioblastoma! Our journey began as interns and project students at the Bio-INvENT Lab. Currently, we're immersed in the cell culture of the U87-MG cell line and focusing on the development of spheroids in agarose microwells, meticulously studying their characterization.
Archana Shreya Shama
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More about us:
Archana: Hello! Working at the Bioinvent Lab has been an incredible experience. I found great fascination in exploring mammalian cell culture and have developed a strong interest in delving deeper into this field. Securing a Summer Research Fellowship at IASC-CSIR:CIMAP Lucknow to work on plant cells has further enriched my passion for cell culturing. Additionally, my involvement in the glioblastoma project has enabled me to establish a valuable network at NIMHANS Bangalore. The lab's working environment is highly conducive to productivity and collaboration.
Shama Hebbar: Hey everyone, I'm currently an undergrad studying biotechnology, and science has always intrigued me. During my second year, I joined a Bio-INvENT, which turned out to be a valuable experience for me. I'm thankful for the opportunity as it has provided me with a lot of knowledge and practical skills, especially in cell culture. I'm on Team Glioblastoma, focusing on developing spheroids and conducting characterizations. Plus, working on fabricating agarose microwells to help with spheroid development. Outside of my studies, I enjoy doodling and reading novels.
Shreya M. Gedigeri: Hi there! I've been interested in mammalian cell culture since the 7th grade, particularly in stem cell biology and its characterization. Utilizing my biotechnology skills, I aim to explore this field further. Bio-Invent Lab offers an excellent platform for me to pursue my interests and has provided opportunities to showcase my talents at prestigious conferences like Schemcon 2023. I've had the privilege of receiving research internships at the Department of Biotechnology, IIT Madras, and the Department of Neurochemistry, NIMHANS, Bangalore. In addition to my research activities, I also enjoy painting, acting, and photography.
More about us:
Saraswathi B L: Hi, I am a Chemical Engineering undergrad. Bio-INvENT Lab has provided a wonderful platform to start my research journey and also exposure to new technologies. I've been able to gain a lot of experience and knowledge in my field. I like to read fiction novels and listen to music.
Apoorva P Shenoy: Hello, I am pursuing a degree in Biotechnology. I have had a keen interest in biomedical research and am grateful for this opportunity in the Bio-INvENT Lab. Alongside research, I enjoy sketching, English literature, and music.