Peer-reviewed Publications
Thanuja MY, Tellakula SS, Suryavanshi SV, Keerthana GS, Chandan V, SH Ranganath. Fusogenic liposome-coated nanoparticles for rapid internalization into donor corneal endothelial tissue to enable prophylaxis before transplantation. Nanoscale Advances (accepted).
A Chakraborty, S Alexander, W Luo, N Al‐Salam, MV Oirschot, SH Ranganath, et al. Engineering multifunctional adhesive hydrogel patches for biomedical applications. Interdisciplinary Medicine, 2023. https://doi.org/10.1002/INMD.20230008.
Shilpashree PS, .... SH Ranganath, et al. Grading the severity of damage to the peri-junctional actomyosin ring and ZO-1 of the corneal endothelium by ensemble learning methods. Journal of Ocular Pharmacology & Therapeutics, 2023; 39(4): 252-274.
Roy D, Udugiri G, Ranganath SH. Evaluation of suitability and detection range of fluorescent dye-loaded nanoliposomes for sensitive and rapid sensing of wide ranging osmolarities. Journal of Liposome Research, 2023 doi.org/10.1080/08982104.2023.2172582.
Anupama C, Abhijith SR, Ranganath SH, Srinivas SP. Experimental oxidative stress breaks down the barrier function of the corneal endothelium. Journal of Ocular Pharmacology & Therapeutics, 2023; 39(1): 70-79.
Thanuja MY, Ranganath SH, Srinivas SP. Role of oxidative stress in the disruption of the endothelial apical functional complex during corneal cold storage. Journal of Ocular Pharmacology & Therapeutics, 2022; 38 (10), 664-681.
Thanuja MY, Ranganath SH, Bonanno JA, Srinivas SP. Nanoliposomes for sensing local osmolarity of the tear film on the corneal surface. Journal of Ocular Pharmacology & Therapeutics, 2022; 38(8): 549-560.
SP Srinivas, Y Sun, Y Povrozin, N Redes, SH Ranganath, et al. Depth-resolved fluorescence lifetime spectroscopy across the cornea in digital frequency domain. Multiphoton Microscopy in the Biomedical Sciences XXII 11965, 2022; 44-53.
Anupama C, Thanuja MY, Sudhir H Ranganath, Kaveet Pandya, Uday B Kompella, Sangly P Srinivas. Oxidative stress induces a breakdown of the cytoskeleton and tight junctions of the corneal endothelial cells. Journal of Ocular Pharmacology & Therapeutics (Sep 2021); accepted.
Thanuja MY, Suma BS, Divyasree Dinesh, Sudhir H Ranganath, Sangly P Srinivas. Microtubule stabilization protects hypothermia-induced damage to the cytoskeleton and barrier integrity of the corneal endothelial cells. Journal of Ocular Pharmacology & Therapeutics, 2021; http://doi.org/10.1089/jop.2021.0036.
Rogers OC, Antony L, Levy O, Joshi N, Simons BW, Dalrymple SL, Rosen DM, Pickering A, Lan H, Kuang H, Ranganath S, et al. Microparticle encapsulation of a prostate-targeted biologic for the treatment of liver metastases in a preclinical model of castration-resistant prostate cancer. Molecular Cancer Therapeutics, 2020; 19(11), 2353-2362.
Thanuja MY, Suma BS, Divyasree Dinesh, Sudhir H Ranganath, Sangly P Srinivas. Microtubule stabilization protects hypothermia-induced damage to the cytoskeleton and barrier integrity of the corneal endothelial cells. Accepted. Journal of Ocular Pharmacology & Therapeutics, 2021.
Rogers OC, Antony L, Levy O, Joshi N, Simons BW, Dalrymple SL, Rosen DM, Pickering A, Lan H, Kuang H, Ranganath S, et al. Microparticle encapsulation of a prostate-targeted biologic for the treatment of liver metastases in a preclinical model of castration-resistant prostate cancer. Molecular Cancer Therapeutics 2020 (accepted).
Thanuja MY, Anupama C, Ranganath SH. Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: So near and yet so far. Advanced Drug Delivery Reviews 2018; 132, 57-80.
SP Srinivas, A Goyal, DP Talele, S Mahadik, RR Sudhir, P Pavani Murthy, S Ranganath, U Kompella, P Padmanabhan. Corneal epithelial permeability to fluorescein in humans by a multi-drop method. PLoS ONE 2018; 13 (6), e0198831.
Yang Z, Concannon J, Ng KS, Seyb K, Mortensen L, Ranganath SH, Gu F, Levy O, Zhao W, Glicksmen M, Karp JM. Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation. Scientific Reports, 2016; 6, 30263.
Ranganath SH, Tong Z, Levy O, Martyn K, Karp JM, Inamdar MS. Controlled inhibition of the mesenchymal stromal cell pro-inflammatory secretome via microparticle engineering. Stem Cell Reports, 2016; 6, 1-14
Levy O, Brennen WN, Han E, Rosen DM, Musabeyezu J, Safaee H, Ranganath S, et al. A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer. Biomaterials 2016; 91, 140-150.
Fu Y, Ong LC, Ranganath SH, Zheng L, Yu S, Chow PKH, Wang CH. A dual tracer 18F-FCH/18F-FDG PET imaging of an orthotopic brain tumor xenograft model. PLoS ONE 2016; 11 (2), e0148123.
Ranganath SH, Levy O, Inamdar MS, Karp JM. Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell 2012; 10(3): 244–258.
Ranganath SH, Tan AL, He F, Krantz WB, Wang CH. Control and enhancement of perm-selectivity of membrane-based microcapsules for favorable biomolecular transport and immunoisolation. AIChE Journal 2011; 57: 3052-3062.
Ranganath SH, Fu Y, Arifin DY, Kee I, Zheng L, Lee HS, Chow PKH, Wang CH. The use of submicron/nanoscale PLGA implants to deliver paclitaxel with enhanced pharmacokinetics and therapeutic efficacy in intracranial glioblastoma in mice. Biomaterials 2010; 31: 5199-5207.
CH Wang, SH Ranganath. (Editorial) Current formulations and techniques of drug/gene delivery for targeted therapy and tissue engineering. Current Pharmaceutical Design 2010; 16(21): 2296-2297.
Ranganath SH, Kee I, Krantz WB, Chow PKH, Wang CH. Hydrogel matrix entrapping PLGA-paclitaxel microspheres: Drug delivery with near zero-order release and implantability advantages for intracranial chemotherapy. Pharmaceutical Research 2009; 26: 2101-2114.
Ong BYS, Ranganath SH, Lee LY, Lu F, Lee HS, Sahinidis NV, Wang CH. Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme. Biomaterials 2009; 30: 3189-3196.
Lee LY, Ranganath SH, Fu Y, Zheng JL, Lee HS, Wang CH, Smith KA. Paclitaxel release from micro-porous PLGA disks. Chemical Engineering Science 2009; 64: 4341-4349.
Ranganath SH, Wang CH. Biodegradable microfiber implants delivering paclitaxel for the post-surgical chemotherapy against malignant glioma. Biomaterials 2008; 29: 2996-3003.
Loh KC, Ranganath S. External-loop fluidized bed airlift bioreactor (EFBAB) for the cometabolic biotransformation of 4-chlorophenol (4-cp) in the presence of phenol. Chemical Engineering Science 2005; 60(22): 6313-6319.
Book Chapter
Ranganath SH, Thanuja MY, Anupama C, Manjunatha TD. (2021) Systemic Drug Delivery to the Posterior Segment of the Eye: Overcoming Blood–Retinal Barrier Through Smart Drug Design and Nanotechnology. In: Tripathi A., Melo J.S. (eds) Immobilization Strategies. Gels Horizons: From Science to Smart Materials. Springer, Singapore. https://doi.org/10.1007/978-981-15-7998-1_6.
Waters RM, Maloney R, Ranganath SH, Hsieh, HY, Paul A. Nano- and microscale delivery systems for cardiovascular therapy. Microscale Technologies for Cell Engineering, 2016; 269-289.
Patents (Applied/Granted)
Kapuganti JG, Ranganath SH. A formulation and a method for inducing defense response in plants. Provisional Patent Application, 2020. 202011019481.