Papers (2015~2022)

Acetaldehyde induces NER repairable mutagenic DNA lesions.

Sonohara Y, Takatsuka R, Masutani C, Iwai S, Kuraoka I.

Carcinogenesis. 2022 Feb 11;43(1):52-59. doi: 10.1093/carcin/bgab087.

PMID: 34546339

Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA.

Endo M, Kim JI, Shioi NA, Iwai S, Kuraoka I.

Open Biol. 2021 Oct;11(10):210148. doi: 10.1098/rsob.210148. Epub 2021 Oct 20.

PMID: 34665969

An Arrhythmic Mutation E7K Facilitates TRPM4 Channel Activation via Enhanced PIP₂ Interaction.

Hu Y, Li Q, Kurahara LH, Shioi N, Hiraishi K, Fujita T, Zhu X, Inoue R.

Cells. 2021 Apr 22;10(5):983. doi: 10.3390/cells10050983.

PMID: 33922380

Isolation and functional diversity of Bowman-Birk type serine proteinase inhibitors from Hyacinthus orientalis.

Aoki-Shioi N, Terada S, Hellinger R, Furuta Y, Gruber CW.

Biochem J. 2021 Mar 26;478(6):1287-1301. doi: 10.1042/BCJ20201005.

PMID: 33666645.

Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution.

Aoki-Shioi N, Jobichen C, Sivaraman J, Kini RM.

Biochem J. 2020 Oct 30;477(20):3951-3962. doi:10.1042/BCJ20200529.

PMID: 33000863.

SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations.

Takedachi A, Despras E, Scaglione S, Guérois R, Guervilly JH, Blin M, Audebert S, Camoin L, Hasanova Z, Schertzer M, Guille A, Churikov D, Callebaut I, Naim V, Chaffanet M, Borg JP, Bertucci F, Revy P, Birnbaum D, Londoño-Vallejo A, Kannouche PL, Gaillard PHL.

Nat Struct Mol Biol. 2020 May;27(5):438-449. doi: 10.1038/s41594-020-0419-3. Epub 2020 May 11.

PMID: 32398829

Developing towards anti-venom drugs by endogenous inhibitor against the metalloproteinase induced hemorrhage; Rational design of drug and therapeutic potential for snakebite

Narumi Aoki-Shioi , Ayaka Ogura , Yoshifumi Zaitsu , Riku Thuthumi , Isao Kuraoka, R Manjunatha Kini

Toxicon. 2020 Apr 20;177 Suppl 1:S27. doi: 10.1016/j.toxicon.2019.12.023.

PMID: 32634972

Omics Technologies for Profiling Toxin Diversity and Evolution in Snake Venom: Impacts on the Discovery of Therapeutic and Diagnostic Agents.

Modahl CM, Brahma RK, Koh CY, Shioi N, Kini RM.

Annu Rev Anim Biosci. 2020 Feb 15;8:91-116. doi: 10.1146/annurev-animal-021419-083626. Epub 2019 Nov 8.

PMID: 31702940

Effects of acetaldehyde-induced DNA lesions on DNA metabolism.

Tsuruta H, Sonohara Y, Tohashi K, Aoki Shioi N, Iwai S, Kuraoka I.

Genes Environ. 2020 Jan 6;42:2. doi: 10.1186/s41021-019-0142-7. eCollection 2020.

PMID: 31921374 Free PMC Article

Nucleotide excision repair genes shaping embryonic development.

Araújo SJ, Kuraoka I.

Open Biol. 2019 Oct 31;9(10):190166. doi: 10.1098/rsob.190166. Epub 2019 Oct 30.

PMID: 31662099 Free PMC Article

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.

Wu J, Samara NL, Kuraoka I, Yang W.

Mol Cell. 2019 Oct 3;76(1):44-56.e3. doi: 10.1016/j.molcel.2019.06.046. Epub 2019 Aug 20.

PMID: 31444105

Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake.

Shioi N, Tadokoro T, Shioi S, Okabe Y, Matsubara H, Kita S, Ose T, Kuroki K, Terada S, Maenaka K.

J Biol Chem. 2019 Jan 25;294(4):1250-1256. doi: 10.1074/jbc.RA118.006840. Epub 2018 Nov 30.

PMID: 30504218 Free PMC Article

Acetaldehyde forms covalent GG intrastrand crosslinks in DNA.

Sonohara Y, Yamamoto J, Tohashi K, Takatsuka R, Matsuda T, Iwai S, Kuraoka I.

Sci Rep. 2019 Jan 24;9(1):660. doi: 10.1038/s41598-018-37239-6.

PMID: 30679737 Free PMC Article

Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site.

Yukutake M, Hayashida M, Shioi Aoki N, Kuraoka I.

Genes Environ. 2018 Nov 12;40:23. doi: 10.1186/s41021-018-0112-5. eCollection 2018.

PMID: 30459925 Free PMC Article

Fluorescence detection of DNA mismatch repair in human cells.

Ito S, Shiraishi M, Tsuchihashi K, Takatsuka R, Yamamoto J, Kuraoka I, Iwai S.

Sci Rep. 2018 Aug 15;8(1):12181. doi: 10.1038/s41598-018-30733-x.

PMID: 30111891 Free PMC Article

An assay to detect DNA-damaging agents that induce nucleotide excision-repairable DNA lesions in living human cells.

Takatsuka R, Ito S, Iwai S, Kuraoka I.

Mutat Res. 2017 Aug;820:1-7. doi: 10.1016/j.mrgentox.2017.05.009. Epub 2017 May 22.

PMID: 28676261

Facile preparation of a fluorescent probe to detect the cellular ability of nucleotide excision repair.

Tawarahara H, Kuraoka I, Iwai S.

Anal Biochem. 2017 Jun 1;526:71-74. doi: 10.1016/j.ab.2017.03.023. Epub 2017 Mar 30.

PMID: 28366639

Inosine-specific ribonuclease activity of natural variants of human endonuclease V.

Kim JI, Tohashi K, Iwai S, Kuraoka I.

FEBS Lett. 2016 Dec;590(23):4354-4360. doi: 10.1002/1873-3468.12470. Epub 2016 Nov 14.

PMID: 27800608 Free Article

Chemical Incorporation of Chain-Terminating Nucleoside Analogs as 3'-Blocking DNA Damage and Their Removal by Human ERCC1-XPF Endonuclease.

Yamamoto J, Takahata C, Kuraoka I, Hirota K, Iwai S.

Molecules. 2016 Jun 11;21(6). pii: E766. doi: 10.3390/molecules21060766.

PMID: 27294910 Free PMC Article

FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks.

Kametani Y, Takahata C, Narita T, Tanaka K, Iwai S, Kuraoka I.

Carcinogenesis. 2016 Jan;37(1):56-62. doi: 10.1093/carcin/bgv159. Epub 2015 Nov 17.

PMID: 26581212

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression.

Barron GA, Goua M, Kuraoka I, Bermano G, Iwai S, Kong Thoo Lin P.

Chem Biol Interact. 2015 Dec 5;242:307-15. doi: 10.1016/j.cbi.2015.10.017. Epub 2015 Oct 21.

PMID: 26499071

Diversity of Endonuclease V: From DNA Repair to RNA Editing.

Kuraoka I.

Biomolecules. 2015 Sep 24;5(4):2194-206. doi: 10.3390/biom5042194. Review.

PMID: 26404388 Free PMC Article

Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.

Takahata C, Masuda Y, Takedachi A, Tanaka K, Iwai S, Kuraoka I.

Carcinogenesis. 2015 Aug;36(8):841-51. doi: 10.1093/carcin/bgv078. Epub 2015 May 29.

PMID: 26025908

Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.

Ito S, Kuraoka I.

DNA Repair (Amst). 2015 Aug;32:52-57. doi: 10.1016/j.dnarep.2015.04.013. Epub 2015 May 1. Review.

PMID: 25956859

An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions.

Sonohara Y, Iwai S, Kuraoka I.

Genes Environ. 2015 Aug 1;37:8. doi: 10.1186/s41021-015-0014-8. eCollection 2015.

PMID: 27350805 Free PMC Article

The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability.

Guervilly JH, Takedachi A, Naim V, Scaglione S, Chawhan C, Lovera Y, Despras E, Kuraoka I, Kannouche P, Rosselli F, Gaillard PHL.

Mol Cell. 2015 Jan 8;57(1):123-37. doi: 10.1016/j.molcel.2014.11.014. Epub 2014 Dec 18.

PMID: 25533188 Free Article

Flavorase, a novel non-haemorrhagic metalloproteinase in Protobothrops flavoviridis venom, is a target molecule of small serum protein-3.

Shioi N, Nishijima A, Terada S.

J Biochem. 2015 Jul;158(1):37-48. doi: 10.1093/jb/mvv017. Epub 2015 Feb 13.

PMID: 25681613

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