2013年

Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helices.
Tanaka T, Kuroda K, Ikeda M, Wakita T, Kato N, Makishima M.
J. Lipid Res., 54:881-892 (2013)

PML tumor suppressor protein is required for HCV production.
Kuroki M, Ariumi Y, Hijikata M, Ikeda M, Dansako H, Wakita T, Shimotohno K, Kato N.
Biochem. Biophys. Res. Commun., 430:592-597 (2013)

Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin.
Mori K, Hiraoka O, Ikeda M, Ariumi Y, Hiramoto A, Wataya Y, Kato N.
Hepatology, 58(4):1236-44 (2013)

Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy.
Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Kirikoshi H, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S.
Biochem Biophys Res Commun., 432:326-332 (2013)

Direct targeting of proteins to lipid droplets demonstrated by time-lapse live cell imaging.
Tanaka T, Kuroda K, Ikeda M, Kato N, Shimizu K, Makishima M.
J Bioscience and Bioengineering, 116(5):620-623 (2013)

Hepatic triglyceride lipase plays an essential role in changing the lipid metabolism in genotype 1b hepatitis C virus replicon cells and hepatitis C patients.
Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Fujita K, Kirikoshi H, Takahashi J, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S.
Hepatol. Res., 43(11):1190-8 (2013)

Suppressive effect of the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on hepatitis C virus replication via epigenetic changes in host cells.
Sato A, Saito Y, Sugiyama K, Sakasegawa N, Muramatsu T, Fukuda S, Yoneya M, Kimura M, Ebinuma H, Hibi T, Ikeda M, Kato N, and Saito H.
J. Cell. Biochem., 114(9):1987-1996 (2013)

New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication.
Ueda Y, Takeda M, Mori K, Dansako H, Wakita T, Kim HS, Sato A, Wataya Y, Ikeda M, Kato N.
PLoS ONE., 8(8):e72519 (2013)

Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication.
Ban S, Ueda Y, Ohashi M, Matsuno K, Ikeda M, Kato N, Miyachi H.
Bioorg. Med. Chem. Letters., 23(17):4774-4778 (2013)

Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virus.
Shen H, Yamashita A, Nakakoshi M, Yokoe H, Sudo M, Kasai H, Tanaka T, Fujimoto Y, Ikeda M, Kato N, Sakamoto N, Shindo H, Maekawa S, Enomoto N, Tsubuki M, Moriishi K.
PLoS ONE., 8(12):e82299 (2013)

Interaction of the phospholipid scramblase 1 with HIV-1 Tat results in the repression of Tat-dependent transcription.
Kusano S, Eizuru Y.
Biochem Biophys Res Commun., 433(4):438-44 (2013)