DDX3 DEAD box RNA helicase is required for hepatitis C virus (HCV) RNA replication.
Ariumi Y, Kuroki M, Abe K, Dansako H, Ikeda M, Wakita T, Kato N.
J. Virol., 81(24):13922-26 (2007)
A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication.
Kim SS, Peng F, Lin W, Choe WH, Sakamoto N, Kato N, Ikeda M, Schreiber SL, Chung RT.
Gastroenterology, 132(1): 311-20 (2007)
Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon.
Ikeda M, Kato N.
J. Pharmacol. Sci., 105(2):145-50 (2007)
Limited suppression of the interferon-beta production by hepatitis C virus serine protease in cultured human hepatocytes.
Dansako H, Ikeda M, Kato N.
FEBS J., 274(16):4161-76 (2007)
Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture.
Yano M, Ikeda M, Abe K, Dansako H, Ohkoshi S, Aoyagi Y, Kato N.
Antimicrob. Agents Chemother., 51(10):3756-9 (2007)
Modulation of host metabolism as a target of new antivirals.
Ikeda M, Kato N.
Adv. Drug Deliv. Rev., 59(12):1277-89 (2007)
Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA.
Abe K, Ikeda M, Dansako H, Naka K, Kato N.
Virus Res., 125(1):88-97 (2007)
Identification of Novel Epoxide Inhibitors of HCV Replication Using a High-Throughput Screen.
Peng LF, Kim SS, Matchacheep S, Lei X, Su S, Lin W, Runguphan W, Choe WH, Sakamoto N, Ikeda M, Kato N, Beeler AB, Porco JA Jr, Schreiber SL, Chung RT.
Antimicrob. Agents Chemother., 51(101):3756-9 (2007)
Serum-free cell culture system supplemented with lipid-rich albumin for hepatitis C virus (strain O of genotype 1b) replication.
Abe K, Ikeda M, Ariumi Y, Dansako H, Kato N.
Virus Res., 125(2):162-8 (2007)
Tandem repeats of lactoferrin-derived anti-hepatitis C virus peptide enhance antiviral activity in cultured human hepatocytes.
Abe K, Nozaki A, Tamura K, Ikeda M, Naka K, Dansako H, Hoshino H, Tanaka K, Kato N.
Microbiol. Immunol., 51(1):117-25 (2007)
Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities.
Ueda S, Oishi S, Wang ZX, Araki T, Tamamura H, Cluzeau J, Ohno H, Kusano S, Nakashima H, Trent JO, Peiper SC, Fujii N.
J Med Chem., 50(2):192-8 (2007)