2005年

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the TLR3 adaptor protein TRIF.
Li K, Foy E, Ferreon JC, Nakamura M, Ikeda M, Ray SC, Gale M Jr, Lemon SM.
Proc. Natl. Acad. Sci. USA, 102(8):2992-7 (2005)

Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system.
Ikeda M, Abe K, Dansako H, Nakamura T, Naka K, Kato N.
Biochem. Biophys. Res. Commun., 329(4):1350-9 (2005)

Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha.
Naka K, Ikeda M, Abe K, Dansako H, Kato N.
Biochem. Biophys. Res. Commun., 330(3):871-9 (2005)

Interferon resistance of hepatitis C virus replicon-harboring cells is caused by functional disruption of type I interferon receptors.
Naka K, Takemoto K, Abe K, Dansako H, Ikeda M, Shimotohno K, Kato N.
J. Gen. Virol., 86(10):2787-92 (2005)

cDNA microarray analysis to compare HCV subgenomic replicon cells with their cured cells.
Abe K, Ikeda M, Dansako H, Naka K, Shimotohno K, Kato N.
Virus Res., 107(1):73-81 (2005)

Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture.
Kato N, Nakamura T, Dansako H, Namba K, Abe K, Nozaki A, Naka K, Ikeda M, Shimotohno K.
J. Gen. Virol., 86(3):645-56 (2005)

cDNA microarray analysis of lactoferrin expression in non-neoplastic human hepatocyte PH5CH8 cells.
Tamura T, Nozaki A, Abe K, Dansako H, Naka K, Ikeda M, Tanaka K, Kato N.
Biochim. Biophys. Acta., 1721(1-3):73-80 (2005)

Hepatitis C virus proteins exhibit conflicting effects on the interferon system in human hepatocyte cells.
Dansako H, Naka K, Ikeda M, Kato N.
Biochem. Biophys. Res. Commun., 336(2):458-68 (2005)

Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.
Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N.
J Med Chem., 48(2):380-91 (2005)

Elevated immunoglobulin G antibodies to the proline-rich amino-terminal region of Epstein-Barr virus nuclear antigen-2 in sera from patients with systemic connective tissue diseases and from a subgroup of Sjögren's syndrome patients with pulmonary involvements.
Yamazaki M, Kitamura R, Kusano S, Eda H, Sato S, Okawa-Takatsuji M, Aotsuka S, Yanagi K.
Clin Exp Immunol., 139(3):558-68 (2005)

Monoclonal antibodies against regions topologically surrounding the homodimeric beta-barrel interface of Epstein-Barr virus nuclear antigen-1.
Eda H, Ishii Y, Obayashi M, Harada S, Ito S, Fujita T, Ikeda M, Kusano S, Kitamura R, Suzuki C, Hara T, Watanabe M, Satoh H, Sugihara K, Yanagi K.
Virus Res., 109(1):87-94 (2005)