All of the processing handled by the BASIC program with output to the BASIC console, all user interaction with the program via TiddlyWiki controls.
Check out the "Sunshine" Sample Application
Imagine TiddlyWiki and a BASIC program (or even many BASIC programs) working together, each specializing in handling whatever component(s) / aspect(s) of some overall purpose.
Say, for example, TiddlyWiki providing the GUI layer for a BASIC program, and the BASIC program providing the processing work (just returning values to TiddlyWiki and/or providing graph rendering in a console window.)
Check out the two examples in this TiddlyWiki: a ridiculous calculator that just sums two values and (scroll down) a graphics program that allows adjusting colors via TiddlyWiki widgets.
Imagine a game in which TiddlyWiki and numerous BASIC programs all working together, each specializing in handling whatever component(s)/aspect(s) of the game ? Hmm...
Might work for certain kinds of games that aren't impacted by short delays caused by communications between the components.