Contributions to Science:

 ➤ Book chapters, Reviews and Articles published- University of Hyderabad

1.  Kumari, N*., Raj, S*. and Babuta, M#  ., 2026. Mitochondrial proteostasis, unfolded protein response, and its relation to cancer. In Proteostasis and Cancer (pp. 79-105). Academic Press. #Corresponding author *Equal contribution 

2. Raj, S. and Babuta, M#  ., 2026. Clinical implications of proteostasis in cancer. In Proteostasis  and Cancer (pp. 215-238). Academic Press. #Corresponding author 

3. Warhade, A. and Babuta, M # ., 2026. Cathepsin Proteases: Physiological Roles and Implications in Disease Pathophysiology. In Enzyme Based Approaches in Cancer Healthcare Management (pp. 241-264). Singapore: Springer Nature Singapore. #Corresponding author 

4. Babuta M, Datta AA, de Carvalho Ribeiro M, Santos, Bruna de Araújo Cardoso dos , Morel C, Copeland C, Ortega-Ribera M, Mehta J, Calenda C, Wang Y, Remotti V, Brezani V, Patel A, Hawryluk D, Szabo G. Cyclic GMP–AMP synthase deficiency predisposes the liver to alcohol- induced cell death and ER stress. Hepatology Communications 10(3):e00908, March 2026. DOI: 10.1097/HC9.0000000000000908 9 

5. Osataphan S, Patell R, Babuta M, et al. The efficacy of rosuvastatin to reduce circulating tissue factor extracellular vesicles after ovarian cancer surgery. Blood Adv. 2025;9(17):4472- 4476. doi:10.1182/bloodadvances.2025016107. PMID: 40472284. 

➤Articles, Reviews and Book chapters published- Postdoctoral studies

1.  Hsieh YC, Babuta M, Siegenberg H, Nagesh PT, Yu Y, Tu W, Sterling RK, Szabo G; AlcHepNet investigators. The impact of obesity on inflammatory cytokines and 90- and 180- day survival in patients with alcohol-associated hepatitis. Clin Transl Gastroenterol. 2026 Jul 1. doi: 10.14309/ctg.0000000000001066. Epub ahead of print. PMID: 42386208. 

2. Ortega-Ribera M, Joshi R, Guixé-Muntet S, Brezani V, Thevkar Nagesh P, Brezani V, Patel A, Zhuang Y, Babuta M, Gracia-Sancho J, Szabo G. Transcriptome of monocytes from liver, brain and bone marrow reveals organ-specific features in aging and alcohol misuse. JHEP Rep. 2025;7(12):101603. Published 2025 Oct 9. doi:10.1016/j.jhepr.2025.101603 

3. Ortega-Ribera M, Zhuang Y, Babuta M, Brezani V, Joshi RS, Zsengeller Z, Thevkar Nagesh P, Wang Y, Bronson R, Szabo G. A Novel Multi-organ Male Model of Alcohol-induced Acute- on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition. Cell Mol Gastroenterol Hepatol. 2024 Dec 20; 101446. PMID: 39710168. 

4. Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, Copeland C, Zhuang Y, Wang Y, Cho Y, Joshi R, Brezani V, Hawryluk D, Datta AA, Mehta J, Nasser I, Szabo G. Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis. Gut. 2024 Oct 07; 73(11):1854-1869. PMID: 38777573. 

5. Nagesh PT, Cho Y, Zhuang Y, Babuta M, Ortega-Ribera M, Joshi R, Brezani V, Patel A, Datta AA, Brezani V, Hsieh YC, Ramos A, Mehta J, Copeland C, Kanata E, Jiang ZG, Vlachos I, Asara J, AlcHepNet Consortium, Szabo G. In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis. Sci Transl Med. 2024 Aug 07; 16(759):eadg1915. PMID: 39110779. 

6. Babuta M, Morel C, de Carvalho Ribeiro M, Datta AA, Calenda C, Copeland C, Nasser I, Szabo G. A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis. Hepatol Commun. 2024 Jul 01; 8(7). PMID: 38896082. 

7. Babuta M, Nagesh PT, Datta AA, Remotti V, Zhuang Y, Mehta J, Lami F, Wang Y, Szabo G. Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1ß Axis in the Liver. Cells. 2024 Jun 01; 13(11). PMID: 38891092. 

8. Sinusoidal cell interactions—From soluble factors to exosomes. Martí Ortega-Ribera*, Mrigya Babuta*, Gyongyi Szabo 2024. Academic Press *Contributed Equally 

9. Ortega-Ribera M, Zhuang Y, Brezani V, Thevkar Nagesh P, Joshi RS, Babuta M, Wang Y, Szabo G. G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF. Front Cell Dev Biol. 2024; 12:1347395. PMID: 38419842. 

10. de Carvalho Ribeiro M, Babuta M, Szabo G. Reply: Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology. 2024 Feb 01; 79(2):E28-E29. PMID: 37972945. 

11. Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, Lee YR, Pan L, Kaelin WG, Yuan J, Wei W. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nat Cell Biol. 2023 Jul; 25(7):950-962. PMID: 37400498. 

12. Zhang T, Xu D, Trefts E, Lv M, Inuzuka H, Song G, Liu M, Lu J, Liu J, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, Xie X, Dang F, Guan D, Men Y, Jiang S, Jiang C, Dai X, Liu J, Wang Z, Yan P, Wang J, Tu Z, Babuta M, Erickson E, Hillis AL, Dibble CC, Asara JM, Szabo G, Sicinski P, Miao J, Lee YR, Pan L, Shaw RJ, Yuan J, Wei W. Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science. 2023 06 30; 380(6652):1372- 1380. PMID: 37384704. 

13. de Carvalho Ribeiro M, Cho Y, Mehta J, Wang X, Babuta M, Copeland C, Hussein H, Catalano D, Wang Y, Szabo G. Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis. Liver Int. 2023 09; 43(9):1937-1949. PMID: 37222257. 

14. de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology. 2023 07 01; 78(1):225- 242. PMID: 36862512. 

15. Cho Y, Bukong TN, Tornai D, Babuta M, Vlachos IS, Kanata E, Catalano D, Szabo G. Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis. J Hepatol. 2023 01; 78(1):28-44. PMID: 36063965. 

16. Babuta M, Szabo G. Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases. J Leukoc Biol. 2022 Jan; 111(1):75-92. PMID: 34755380. 

17. Bala S † , Babuta M † , Catalano D, Saiju A and Szabo G. Alcohol Promotes Exosome Biogenesis and Release via Modulating Rabs and miR-192 Expression in Human Hepatocytes. Front. Cell Dev. Biol., 14 Jan, 2022 https://doi.org/10.3389/fcell.2021.787356. † - Contributed equally 

18. Transcriptomics and Their Importance. Transcriptomics in Understanding the Basic Biology of the Cell. Mrigya Babuta # and Kunwar Somesh Vikaramdeo#.2022 Nova Science Publisher # Corresponding Author

19. Bala S, Ganz M, Babuta M, Zhuang Y, Csak T, Calenda CD, Szabo G. Steatosis, inflammasome upregulation, and fibrosis are attenuated in miR-155 deficient mice in a high fat- cholesterol-sugar diet-induced model of NASH. Lab Invest. 2021 Aug 27. PMID: 34453120. 

20. Bala S, Calenda CD, Catalano D, Babuta M, Kodys K, Nasser IA, Vidal B, Szabo G. Deficiency of miR-208a Exacerbates CCl4-Induced Acute Liver Injury in Mice by Activating Cell Death Pathways. Hepatol Commun. 2020 Oct; 4(10):1487-1501. PMID: 33024918. 

21. Babuta M, Furi I, Bala S, Bukong TN, Lowe P, Catalano D, Calenda C, Kodys K, Szabo G. Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro- RNA 155 in Alcoholic Liver Disease. Hepatology. 2019 12; 70(6):2123- 2141. PMID: 31090940. 

➤ Articles, Reviews and Book chapters published from PhD work (Predoctoral studies)

1. Pinotsis N*, Zielinska K*, Babuta M*, Arolas JL*, Kostan J, Khan MB, Schreiner C, Salmazo A, Ciccarelli L, Puchinger M, Gkougkoulia EA, Ribeiro EA, Marlovits TC, Bhattacharya A, Djinovic-Carugo K. Calcium modulates the domain flexibility and function of an a-actinin similar to the ancestral a-actinin. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22101- 22112. PMID: 32848067. *- Contributed equally 

2. Babuta M, Bhattacharya S, Bhattacharya A. Entamoeba histolytica and pathogenesis: A calcium connection. PLoS Pathog. 2020 05; 16(5):e1008214. PMID: 32379809. 

3. Kumari P, Babuta M, Bhattacharya A, Gourinath S. Structural and functional characterisation of phosphoserine phosphatase, that plays critical role in the oxidative stress response in the parasite Entamoeba histolytica. J Struct Biol. 2019 05 01; 206(2):254-266. PMID: 30935984.

4. Babuta M, Kumar S, Gourinath S, Bhattacharya S, Bhattacharya A. Calcium-binding protein EhCaBP3 is recruited to the phagocytic complex of Entamoeba histolytica by interacting with Arp2/3 complex subunit 2. Cell Microbiol. 2018 Dec; 20(12):e12942. PMID: 30133964. Mansuri MS, Babuta M, Ali MS, Bharadwaj R, Deep jhingan G, Gourinath S, Bhattacharya S, Bhattacharya A. Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required for activity and regulation of erythrophagocytosis. Sci Rep. 2016 Jan 07; 6:16969. PMID: 26739245.  

5. Babuta M, Mansuri MS, Bhattacharya S, Bhattacharya A. The Entamoeba histolytica, Arp2/3 Complex Is Recruited to Phagocytic Cups through an Atypical Kinase EhAK1. PLoS Pathog. 2015 Dec; 11(12):e1005310. PMID: 26646565. 

6. Protein Kinases of the Parasitic Protist Entamoeba histolytica. Somlata, Mrigya Babuta, Sudha Bhattacharya, Alok Bhattacharya. 2013 Wiley‐VCH Verlag GmbH & Co. KGaA 

7. Somlata, Agrahari M, Babuta M, Bhattacharya S, Bhattacharya A. Autophosphorylation of Ser428 of EhC2PK plays a critical role in regulating erythrophagocytosis in the parasite Entamoeba histolytica. J Biol Chem. 2012 Mar 30; 287(14):10844-52. PMID: 22753771.