Cell Membrane Organization

Our research group is dedicated to exploring the intricate organization and dynamics of the cell membrane, focusing on its key components such as lipids, proteins, and other molecular players. The cell membrane is a critical structure that not only defines the boundaries of the cell but also plays a vital role in various cellular processes, including signaling, transport, and interaction with the extracellular environment.

We investigate the diverse types of lipids that make up the lipid bilayer, examining how their composition and distribution contribute to membrane fluidity, curvature, and the formation of specialized microdomains known as lipid rafts. These lipid rafts serve as platforms for the assembly of signaling molecules and play a crucial role in cellular communication and signal transduction.

Our research also delves into the various membrane proteins embedded within or associated with the lipid bilayer. These proteins perform a wide range of functions, including acting as receptors, channels, transporters, and enzymes. We study how the spatial and temporal organization of these proteins within the membrane affects their function and how they interact with other cellular components to regulate processes such as nutrient uptake, ion transport, and cell signaling.

By addressing the organization and function of cell membrane components, our research seeks to uncover the fundamental principles that underlie membrane biology. This knowledge has important implications for understanding various physiological processes and disease states, including cancer, neurodegenerative diseases, and infectious diseases. Ultimately, our goal is to contribute to the development of novel therapeutic strategies targeting membrane-associated pathways and to enhance our overall understanding of cellular function and organization.