When the Catholic School in Tiker, a nearby sitio, ran by the Holy Spirit Sisters, closed in 1936, the barangay people felt a need to open a barrio school to accommodate the children in one of the sitios of Budac, Tayum, Abra. An-anaao was chosen to be the seat of the new school because it was the geographical center of the barrio. Grade 1 was opened in 1937 with 30 pupils under Mr. Vicente Tadeo as the first teacher. The ages of the pupils were notable having 12 years old as the youngest and 18 as the oldest pupils. The class was temporarily seated at the ground floor of the Millare residence.

                    In 1938, Grade 2 was opened. The school was transferred to make shift but jointly created by the parents and the barangay officials on a vacant lot owned by Galicano Millare. He donated the said lot with an area of 3,208 sq. meters. A school building was built in 1939 to provide the pupils with more formal learning. Grades 3 and 4 were opened having been fused and handled by a teacher. During the outbreak of World War II, the school was closed in 1940 and was reopened after the liberation in 1946.

                    In 1947, Grade 5 was opened. Additional classrooms were built. The school became a complete elementary school in 1950 with 18 pupils as its first graduates. From then, increase of enrolment was very eminent. More children from nearby barangays came to study until 6 teachers held 6 classes. Additional ground was then given and school building was built. The lot was formally donated to the school in 1990.

                    Through the support and effort of SDO Abra and LGU of Tayum Officials, An-anaao Elementary School was officially converted to An-anaao Integrated School last April 10, 2017 with 42 learners as first students in grade 7. Mr. Janssen P. Millare and Miss Rhickcelle T. Alcantara are the pioneer teachers, and the school principal is Mr. Eugenio P. Millare.

                    The 3-room Bagong Lipunan building of An-anaao Integrated School was totally razed by fire on September 23, 2018 at about 2:00 o’clock in the morning. The said building was the oldest structure of the school in the year 2018. It was used as the Office of the School Principal, Guidance Office and Instructional Classroom for Grade 7.

                    In the School Year 2021-2022, An-anaao Integrated School opened its first Senior High School offering Academic Track: Humanities and Social Sciences (HUMSS) with 28 enrolled students and Technical Vocational Livelihood: Information and Communication Technology (ICT)- Computer System Servicing NCII with 29 enrolled learners as first students of Grade 11.