In melt electrowriting (MEW) process, a high voltage is applied to a polymer melt flowing from a nozzle. The resulting electric field between the nozzle and the substrate stabilizes the polymer melt jet even at very low flow rates/back-pressures. Using this technique, it is possible to fabricate well-ordered patterns at the microscale. In this project, we fabricated well-ordered scaffolds by MEW of PLA and PCL filaments and then, used MTT assay to evaluate the ability of the scaffolds for cell growth and proliferation. Below, you can observe the well-ordered scaffolds fabricated using MEW technique as well as the result of cell culture on the surface of the scaffolds.
Neat PCL scaffold
Neat PLA scaffold
L929 cell on PCL scaffold
L929 cell on PLA scaffold
Melt electrowriting process for PLA fibers