Research

The revolution in sequencing technologies has given the momentum for the emerging genomics and personalized medicine era that led to great discoveries, particularly in cancer research. Translating these findings into the clinic, however, has moved at a much slower pace. It is evident that cancer genomic variation, the somatic changes in cancer cells and germline variants in normal cells, influence the disease outcome and response to treatment.

The Alachkar lab is functional and translational genomics lab focused on applying genomic information to the identification and functional characterization of cancer targets. We conduct preclinical and clinical studies to develop novel targeted therapeutic approaches to treat acute myeloid leukemia.