People

Houda Alachkar

PharmD, PhD

Principal Investigator

Houda Alachkar is an Associate Professor at the University of Southern California, School of Pharmacy.

Email: alachkar@usc.edu



Current Lab Members

Postdoctoral Scholars

Mateusz Pospiech

Mateusz Pospiech is a Postdoctoral Scholar at the University of Southern California, School of Pharmacy. Mateusz's research focuses on  neoantigents and characterization of TCR repertoire of acute myeloid leukaemia and their function in the development of personalized cell therapies.

Mateusz received his undergraduate and graduate degree in Chemistry from Poland. He purused a PhD from Swasnea University Medical School, under the mentorship of Professor Martin Sheldon where he focused on the use of bisphosphonate inhibitors of squalene synthase to provide cytoprotection against cholesterol-dependent cytolysins.

Email: pospiech@usc.edu  

Soheila Rezaei Adariani

Soheila is our new postdoctoral researcher.  Before joining our lab, Soheila was as a Postdoctoral Researcher in the group of Prof. Waldmann at Max Planck Institute of Molecular Physiology in Germany. She studied characterization of biologically active molecules that have been identified as hit substances in a high-throughput phenotypic screening to determine their target or mode of action as potential drug targets by utilizing a wide range of cellular biology methods as well as cell painting methods. 

She earned her PhD in Biochemistry, Biophysics and Molecular Biology from medical faculty of University of Düsseldorf, where she conducted research on the understanding the molecular mechanism of signal transduction pathways such as RAS signaling using biophysical and biochemical methods. She has developed skills in Cell Biology, Biochemistry, Biophysics, Molecular & Cellular Biology, and various analytical and experimental techniques.

Email: soheila.rezaei@usc.edu

PhD Students

Atham Ali

Atham is a fifth-year PhD candidate at the University of Southern California, School of Pharmacy. Atham's research focuses on the interaction and targeting of CD99 and FLT3 to eliminate leukemic stem cells in AML. 

Atham received his undergraduate degree in Public Health Science at the University of California, Irvine, where he conducted research in Dr. Ehlerts Lab and helped develop a novel method for analyzing the activity of agonists for eliciting responses through G protein-coupled receptors.

Email: athamali@usc.edu 

Yiting (Ophelia) Meng

Ophelia is a third-year PhD candidate in Pharmaceutical Sciences at USC School of Pharmacy. Ophelia received her undergraduate degree in Biology with a minor in Biochemistry at University of Oregon.

Email: yitingme@usc.edu 

Sandra Onyemaechi

Sandra is a third year PhD student in Pharmaceutical Sciences at USC School of Pharmacy. Sandra received her undergraduate degree from University of Texas at Austin.

Email: onyemaec@usc.edu 

Amani Alqahtani

Amani is a first year PhD student in Clinical and Experimental Therapeutics at USC School of Pharmacy. Amani received her undergraduate degree from King Saud University in Saudi Arabia.

Email: amanialq@usc.edu 

Master's Students

Xiaochen Zhang

Xiaochen is a second year Master in Clinical and Experimental Patient Therapeutics (CXPT). She earned her bachelor's degree in Pharmacy at Zhengzhou University. 

Her research project entails establishing and characterizing a Cre-inducible apolipoprotein C2 (Apoc2) knockout mouse models to study the rules of Apoc2 in normal hematopoiesis. 

Email: xzhang39@usc.edu

Shephali Milind Kadam 

Shephali is a second year Master in Pharmaceutical Sciences (PSCI). She earned her bachelor’s degree in Pharmacy and MBA in Pharmaceutical Technology at NMIMS university.

Her research mainly focuses on characterizing the effects of CD99 on T cells.

email: shephali@usc.edu

Kanaka Dhuri

Kanaka is a second year Master's student in Molecular Pharmacology and Toxicology (MPTX). She completed her Bachelor's degree in Pharmacy from University of Mumbai. 

Her research focuses on examining the role of Apolipoprotein C2 (APOC2) in Hypomethylating agent (HMA) therapy resistance in Acute Myeloid Leukemia (AML) and exploiting the APOC2-CD36 axis as a treatment strategy to sensitize AML to HMAs.

Email: kdhuri@usc.edu

Wenda Zhu

Wenda is a first-year Master's student in Pharmaceutical Sciences at USC School of Pharmacy. He received his undergraduate degree from Southeast University in China. 

Email: wendazhu@usc.edu

Qianqian Peng

Qianqian Peng is a first-year Master's student in Pharmaceutical Sciences at USC School of Pharmacy. She received her undergraduate degree from The Ohio State University.  

Email: pengqian@usc.edu

Yiyu Xiao

Yiyu Xiao is a first-year Master student in Pharmaceutical Sciences at USC School of Pharmacy. She earned her undergraduate degree in Sun Yat-Sen University in China.

Email: yiyuxiao@usc.edu

Undergraduate Students

Ryan Chu

Ryan is a third Year Undergraduate pursuing a B.S. in Pharmacology and Drug Development. 

His research mainly focuses on midostaurin-resistant AML cells and their response to FLT3/CD99 targeting. 

Email: rlchu@usc.edu

Former PhD Students

Kerui Peng

Kerui is a second-year PhD candidate at the University of Southern California, School of Pharmacy.  Kerui’s research focus is the mining, modeling, and analysis of the T cell receptor repertoire to predict disease prognosis and treatment outcomes. 

Email: keruipen@usc.edu 

Tian Zhang

Tian graduated with a Ph.D from the Medical Biology program at the Keck School of Medicine, University of Southern California in Spring 2020.

Email: zhangtia@usc.edu 

Pooja Vaikari

Pooja graduated with a Ph.D in Clinical and Experimental Therapeutics from the University of Southern California, School of Pharmacy in Spring 2020.  Her research focused on understanding the role of CD99 in acute myeloid leukemia.

Email: vaikari@usc.edu

John Beckford

John graduated with a PhD in  Clinical and Experimental Therapeutics from the University of Southern California, School of Pharmacy in Spring 2021. 

Email: jbeckfor@usc.edu

Lucas Gutierrez

Lucas graduated with a PhD in  Clinical and Experimental Therapeutics from the University of Southern California, School of Pharmacy in Spring 2021.  Lucas's research project focuses on identification and validation of leukemia neoantigens. He is also investigating the impact of FLT3 inhibitors on T cells function and repertoire in patients with AML.

Email: lkgutier@usc.edu

Sharon Wu

Sharon graduated with a Ph.D in Clinical and Experimental Therapeutics from the University of Southern California, School of Pharmacy in Spring 2020. Sharon is interested in understanding the mitochondrial deregulation in acute leukemias. 

Email: sharongw@usc.edu

Former MS Students

Ritu Chandwani

Ritu is a first year Master's student in Pharmaceutical Sciences at USC School of Pharmacy. Ritu received her undergraduate degree from Mumbai University in India.

Email: rchandwa@usc.edu 

 Yu-Chun (Teresa) Wei 

Teresa is a first year Master's student in Pharmaceutical Sciences at USC school of Pharmacy. Her research focuses on the cloning of T cell receptors for acute myeloid leukemia treatment.

Teresa received her undergraduate degree in Pharmacy from China Medical University in Taiwan.

Email: yuchunwe@usc.edu 

Yuqiao (Aurora) Liu

Aurora is a second year Master's student in Pharmaceutical Sciences at USC School of Pharmacy. Aurora received her undergraduate degree in Pharmaceutical Engineering from Sichuan University in China. 

Email: yuqiao@usc.edu 

Lena Keossayan

Lena is a second year Master's student in Molecular Pharmacology and Toxicology at USC School of Pharmacy. Lena received her undergraduate degree in Biology from University of California, Santa Barbara.

Email: keossaya@usc.edu 

Yang Zhao

Yang is a second year Master's student in Pharmaceutical Sciences at USC School of Pharmacy. Yang received her undergraduate degree in Chemical Engineering and Technology from Hainan University in Haikou, China.

Email: yzhao504@usc.edu 

Mohammed Almatani

Mohammed is a second year Master's student in Molecular Pharmacology and Toxicology at USC School of Pharmacy. Mohammed received his PharmD from Taif University in Saudi Arabia. 

Email: almatani@usc.edu 

Jiawen (Lyn) Yang

Jiawen graduated with MS degree from the University of Southern California, School of Pharmacy. Jiawen is currently a PhD student at the university of Arizona.

Email: jiawenya@usc.edu

Yang Du

Yang graduated with MS degree from the University of Southern California, School of Pharmacy

Email: yangdu@usc.edu

Rucha Deo

Rucha was a former Masters student at the University of Southern California, School of Pharmacy. Rucha is currently research associate at City of Hope

 Email: rdeo@usc.edu

Former high School Students

Anthony Ball

Anthony was a high school student in the Science, Technology and Research (STAR) program from Bravo Medical Magnet High School.

Sasha Kartman

Sasha was a high school student in the Science, Technology and Research (STAR) program from Bravo Medical Magnet High School.