Presentations

Presented to the Department of Translational Neuroscience at Wake Forest University School of Medicine

References for the presentation can be accessed through this link.

This was part of an Upper Midwest Chapter of the Society for Neuroscience Social event held at Cocoon Brewing near Green Bay, WI. Thank you to Cocoon Brewing for sponsoring the presentation. The presentation described some basic information on beverage alcohol, how alcohol travels through the body and reaches the brain, alcohol actions in the brain, how these actions explain alcohol's effects, and some health effects of chronic alcohol use. 

CDC page on alcohol use: https://www.cdc.gov/alcohol/ 

Ben Franklin's collection of terms for being drunk, from the The Pennsylvania Gazette, January 13, 1736/7: https://founders.archives.gov/documents/Franklin/01-02-02-0029 

Thank you to Peace Pie Company for hosting the event and for Dr. Shawn Brown at Marquette Medical Urgent Care for co-presenting this educational evening!

Links to papers and other resources related to the science behind ketamine

Ketamine for Depression: What to Know WebMD article on ketamine.

Penn Medicine Study Gives Peek of How Ketamine Acts as ‘Switch’ in the Brain

The ketamine economy: New mental health clinics are a 'Wild West' with few rules. NPR story about ketamine clinics published on January 30, 2024.

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000). Antidepressant Effects of Ketamine in Depressed Patients. depression, 47, 351-354. Link to PDF. This was the first clinical study evaluating ketamine for treatment-resistant depression

Zanos, P., Brown, K. A., Georgiou, P., Yuan, P., Zarate, C. A., Thompson, S. M., & Gould, T. D. (2023). NMDA receptor activation-dependent antidepressant-relevant behavioral and synaptic actions of ketamine. Journal of Neuroscience, 43(6), 1038-1050. https://www.jneurosci.org/content/jneuro/43/6/1038.full.pdf FREE TO VIEW

de la Salle, S., Choueiry, J., Shah, D., Bowers, H., McIntosh, J., Ilivitsky, V., & Knott, V. (2016). Effects of Ketamine on Resting-State EEG Activity and Their Relationship to Perceptual/Dissociative Symptoms in Healthy Humans. Frontiers in pharmacology, 7, 348. https://doi.org/10.3389/fphar.2016.00348 FREE TO VIEW

NMU's Dr. Amber LaCrosse recently investigated the combined effects of racemic ketamine with fluoxetine (Prozac) on consolidation of fear memories, and these findings are published in the Journal of Pharmacology and Experimental Therapeutics.