The Mapungubwe Hill was the site of a community dating back to the Iron Age. Evidence has shown that it was a prosperous community. Archaeologists also uncovered the famous Golden Rhinoceros of Mapungubwe figurine from the site.

It is located at the Kolope River, south of the confluence of the Limpopo and Shashe rivers and about 15 kilometres (9.3 mi) to the NE of the Venetia Diamond Mine. The National Park borders Mapesu Private Game Reserve to the south. It abuts on the border with Botswana and Zimbabwe, and forms part of the UNESCO Mapungubwe Cultural Landscape and the Greater Mapungubwe Transfrontier Conservation Area.