Luis Felipe Santos Mendes is an Associated Professor at the Group of Biophysics and Structural Biology "Sergio Mascarenhas" - São Carlos Institute of Physics, University of São Paulo. During my Ph.D., I conducted research internships at leading institutions, including the Biomembrane Structure Unit at the University of Oxford (under Prof. Dr. Anthony Watts), the Laboratory für Physikalische Chemie at ETH Zurich (with Prof. Dr. Gunnar Jeschke), and the Department of Chemistry at North Carolina State University (NCSU) (with Prof. Dr. Alex I. Smirnov). My thesis was recognized by the Brazilian Physical Society as the best dissertation in Biological Physics for the 2017–2018 biennium. After completing my Ph.D., I pursued postdoctoral research in the BioNMR group at ETH Zurich (2022–2023) and at FFCLRP/USP (2019–2021). My research focuses on the functional mechanisms of intrinsically disordered proteins (IDPs) and hybrid proteins with ordered and disordered regions (IDPRs). We study these systems in their native, biomolecular condensate, and amyloid states, employing a variety of biophysical and biochemical methods to investigate their roles in physiological and pathological contexts. Our group has extensive expertise in molecular biology techniques, including cloning, subcloning, mutant construction, and expression and purification of soluble and membrane heterologous proteins (E. coli and yeast), as well as advanced biophysical techniques such as Circular Dichroism (conventional and synchrotron radiation-based), Fluorescence Spectroscopy (steady-state and time-resolved), Confocal Microscopies, Magnetic Resonance, Differential Scanning Calorimetry/Fluorimetry (DSC and DSF), MicroScale Thermophoresis (MST), and SEC-MALS.