Scientific Program
Embedded Files
Day 1
16th November 2023
8:30 - 9:00
Registration
Registration
E3 Ligases - Ubiquitination and Signaling
9:00 - 9:10
Welcome
Welcome
9:10 - 9:40
Simona Polo
Simona Polo
Unveiling the Mechanisms of NEDD4-Mediated Polyubiquitin Chain Formation
9:40 - 10:10
Tim Clausen
Tim Clausen
Mysterious E3 Giants in ubiquitin waters
10:10 - 10:25
Rasmus Hartmann-Petersen
Rasmus Hartmann-Petersen
Analyses of protein quality control by deep mutational scanning
10:25 - 10:40
Radoslav Enchev
Radoslav Enchev
TBD
10:40 - 11:00 Coffee Break
11:00 - 11:30
Matthias Peter
Matthias Peter
Substrate targeting by the human GID complex
11:30 - 12:00
Helen Walden
Helen Walden
Regulation of DNA repair by ubiquitin
12:00 - 12:15
Martina Foglizzo
Martina Foglizzo
BRCA1-BARD1 bridges across nucleosomes and “inchworms” on chromatin using multiple interaction modules
12:15 - 12:30
Izabela Sumara
Izabela Sumara
Regulation of nucleoporin homeostasis by UBAP2L
12:30 - 14:30 Lunch Break
14:30 - 15:00
Helle Ulrich
Helle Ulrich
Ubiquiton – re-writing the ubiquitin code
15:00 - 15:30
Achim Werner
Achim Werner
Deciphering ubiquitin-dependent mechanisms of development through human disease mutations
15:30 - 15:45
Monica Gotta
Monica Gotta
Lost in translation: understanding the role of stress granule components in embryonic development
15:45 - 16:00
Valentina Rossio
Valentina Rossio
Comparing DUB specificity across hundreds of ubiquitinated substrates in the Xenopus egg extract
16:00 - 16:30 Coffee Break
16:30 - 17:00
Niels Mailand
Niels Mailand
Coupling ubiquitin- and SUMO-dependent signaling in cellular stress responses
17:00 - 19:00 Poster Session
19.45 Conference Dinner at "Ristorante da Robertino", via Panisperna 231
Day 2
17th November 2023
9:00 - 9:30
Kay Hofman
Kay Hofman
Here be clippases! Searching for unusual deubiquitinases in uncharted territory
9:30 - 10:00
Yogesh Kulathu
Yogesh Kulathu
The role of UFMylation in the birth of proteins at the endoplasmic reticulum
10:00 - 10:15
Antonella Tramutola
Antonella Tramutola
Poly-ubiquitination profile in Down syndrome brain before and after the development of Alzheimer neuropathology.
10:15 - 10:30
Julia Varga
Julia Varga
Protein design protocols for assessing modeled peptide-protein
complexes
10:30 - 11:00 Coffee Break
11:30 - 12:00
Maria Masucci
Maria Masucci
Host cell remodeling by a viral ubiquitin deconjugase
12:00 - 12:30
Leo James
Leo James
Trim-Away: targeted degradation of pathogens and proteins
12:30 - 12:45
Cecile Exertier
Cecile Exertier
Recruitment of Leishmania ubiquitin proteasome system to tackle leishmaniasis: rational design of PROteolysis TArgeting Chimeras against the trypanothione reductase.
12:45 - 13:00
Caio Oliviera
Caio Oliviera
OTUD5 mediated deubiquitination of chromatin-associated proteins
13:00 - 14:30 Lunch Break
14:30 - 15:00
Stefan Knapp
Stefan Knapp
New ways to effectively kill a protein: the development of new protein degraders
15:00 - 15:30
Michele Vendruscolo
Michele Vendruscolo
The thermodynamic hypothesis of protein aggregation
15:30 - 15:45
Marcel Diallo
Marcel Diallo
Tacrolimus-mediated modulation of T-cell activity: insights into the BMP pathway and K29 ubiquitin chains
15:45 - 16:00
Catherine Lindon
Catherine Lindon
Cellular determinants of AURKA degradation by small molecule PROTACs
16:00 - 16:30 Coffee Break
16:30 - 17:00
Norman Davey
Norman Davey
Towards a functional map of the intrinsically disordered proteome
17:00 - 17:30
Andrea Musacchio
Andrea Musacchio
Chromosome segregation: down to mechanisms
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