Former Group Members
Post-doctorals
Dr. Timothy W. Abraham (1992-1995)
Dr. Patricia Pieper (1997-1998)
Dr. George W. Griesegraber (1998-2000)
Dr. Issa Isaac (1999-2001)
Dr. Chuckyung Park (2001-2002)
Dr. Jisook Kim (2001-2004)
Dr. Jilin Chang (2001-2004)
Dr. Terry Davis (2001-2004)
Dr. Tsuifen Chou (2006)
Dr. Phaguni Ghosh (2001-2007)
Dr. Brahma Ghosh (2005-2009)
Dr. Brandie Kovaleski (2008-2010)
Dr. Adrian Fegan (2008-2012)
Dr. Matthew Cuellar (2008-2012)
Dr. Jae-Chul Lee (2010-2012)
Dr. Nigam Kumar (2012-2014)
Dr. Sid Kumarapperuma (2009-2014), Res. Assistant Professor (2014-2017)
Dr. Lakmal Kotelawala (2014-2017)
Dr. Jacob Petersburg (2018)
Dr. Justine Delgado (2018-2020)
Undergraduate Student Researchers Advised
Jennifer Bauer (1992)
Chris Seiffert (1992)
Thomas Lapinski (1992-1993)
Christine Sieg (1994-1995)
Beatrice Chaveca (1993)
Helen Margellos (1995-1996)
Matt McCarthy (1996)
Stephanie Welliver (1997-1998)
Ah Zhou Vang (1997)
Adam Pedersen (1998)
Aarron Kantor (1999-2001)
Jennifer Sorman (2000)
Jane Burnbaum (2000)
Janelle Johnson (2000-2001)
Kara Gleason (2001-2003)
Steve Hinkins (2003-2004)
Caleb Bates (2003-2004)
Jessie Kerns (2003-2004)
Kevin O’Halloran (2003-2005)
Ilya Tikh (2004-2006)
Mohaud Mumin (2006)
David Hapka (2007-2008)
Mike DeMeuse (2007-2008)
Tri Dang (2008-2009)
Quang Cai (2008-2009)
Ryan Holton (2010-2011)
Bryon Loudy (2010-2011)
Morgan Schwock (2011-2012)
Ryan Baumgartner (2010-2012)
Joseph Molde (2011-2012)
Lai Zhang (2012-2013)
Danyang Chen (2011-2013)
Peter Huynh (2009-2013)
Danyang Chen (2011-2013)
Lai Zhang (2012-2013)
Katelyn Palmatier (2012-2014)
Tim Isdahl (2013-2014)
Erik Larsen (2014-2015)
Jialin Liu (2015-2016)
Cher-Ling Ting (2015-2017)
Alex Hendricks (2013-2017)
Andrew Zhou (2014-2017)
Thomas J. Perry (2017-2019)
David Wang (2018-2019)
Victor Boris (2019-2023)
Lynn Wang (2019-2021)
Ethan Redlin (2021-2022)
Jacob Weber (2021-2022)
High School Students Mentored
Do-Hyoung Park (2010-2011)
Luke Brown (2012)
Nandan Raghavan (2012)
Viktor Boris (2019)
Aarya Bommidi (2022)
Michael Setterberg (2023)
Charlo Vasicek (2023)
Graduate Students
Joy M. Nielsen, MS Medicinal Chemistry, 1996, Thesis Title: ”Development of an Antiphosphorylcholine Single Chain Antibody”
Shu-ling Chang, MS Microbial Engineering, 1997, Thesis Title: “The Generation of Single Chain Catalytic Antibodies for Carbamate Hydrolysis”
Edward J. McIntee, Ph.D. Medicinal Chemistry, 1997, Thesis Title: “Synthesis, Biological Activity and Mechanistic Studies of Aromatic Amino Acid Phosphoramidates of Antiviral and Antitumor Nucleosides”
Kristina R. K. Sticha, Ph.D. (Co-advisor with Dr. P. E. Hanna) Pharmacology, 1998, Thesis Title: “N-Acetyltransferases: Studies of Recombinant Enzymes and Bioactivation of Carcinogenic Arylamine Metabolites”
Shu-ling Chang, Ph.D., Microbiology, Immunology and Medical Pathobiology, 1999, Thesis Title: “Mechanistic Studies of Anti-HIV-1 Nucleoside Phosphoramidates”
Heng Song, Ph.D., (Co-advisor with Dr. C. L. Zimmerman) Pharmaceutics, 2000, Thesis Title: “Characterization of the Pharmacokinetics of Amino Acid Phosphoramidates of AZT in Rats”
Vidhya I. Iyer, Ph.D. Medicinal Chemistry, 1998, Thesis Title: “Synthesis and Anti-Breast Cancer Activity of Aromatic Amino Acid Phosphoramidates of Antiviral and Antitumor Nucleosides”
Guruvasuthevan R. Thuduppathy, M.S Microbial Engineering, 2001, Thesis Title: "Design, Development and Evaluation of Ligands for Selective Protein Dimerization"
Jonathan T. C. Carlson, Ph.D. Medicinal Chemistry, 2005, Thesis Title: “Chemically Self-Assembled Protein Nanostructures”
Haiqing Wang, Ph.D., Medicinal Chemistry, 2005, Thesis Title: “Studies of Arylamine N-acetyltransferases (Co-advisor with Dr. P. E. Hanna)
Tsui-Fen Chou, Ph.D., Medicinal Chemistry, 2006, Thesis Title: “Histidine Triad Nucleotide Binding Proteins (Hints): Nucleoside Phosphoramidases and Potential Regulators of Aminoacyl-tRNA Synthetases”
Leila Datoo, M.S., Chemistry, 2008, Thesis Title:”AZT Phosphoramidates as Potential Antibacteiral Agents”
Chen Xing, M. S. (Plan B), Chemistry, 2008, “Construction of Trivalent DHFR Based Oligomers”.
Brian R. White, Ph. D., Medicinal Chemistry, 2009, “Toward Therapeutic Nanoassemblies: The Design and Modeling of Protein-Protein Interactions”.
Yan Jia, Ph. D., Chemistry, 2010, "Development of Eukaryotic Initiation Factor 4E (eIF4E) Antagonists as Potential Anticancer Therapeutics".
Xin Zhou, Ph. D., Medicinal Chemistry, 2010, " Catalytic Mechanism of the Hamster Arylamine N-acetyltransferase 2 (NAT2) and Human Histidine Triad Nucleotide Binding Protein 1 (Hint1)".
Qing Li, Ph. D., Candidate, Chemistry, 2010, “Chemically Self-Assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic".
Sanaa Bardaweel, Ph.D., Medicinal Chemistry, 2010, “Defining the Catalytic and Kinetic Mechanism and Natural Function of the Highly Conserved Acyl-AMP Hydrolase, HINT1".
Shui Li, M. S., Medicinal Chemistry, 2012, “Evaluation of Eukaryotic Initiation Factor 4E (eIF4E) Antagonist 4Ei-1 in Mammalian Breast Cancer and Lung Cancer Cells : Chemosensitizaiton with Low Cytotoxicity”.
Kari Schuett, Ph.D., Medicinal Chemistry, 2013, “Chemically Self-Assembled Antibody Nanorings: A Multifaceted Approach to Anti-Cancer Therapeutics Using Techniques including Drug Delivery, Bispecific Targeting, and T-cell Surface Modifications”.
Jing Liu, MS Plan B, 2013, Chemistry, “Synthesis of Chemical Dimerizers for Assembly of Chemically Self-Assembled Antibody Nanorings.”
Amit Ganger, Ph. D., Medicinal Chemistry, 2014, “Chemically Self-Assembled Antibody Nanostructures for the Delivery of Drug, DNA, Proteins and Cells.”
Jing Jing Shen, Ph. D., Medicinal Chemistry, 2016, "Self-Assembled Antibody Nanorings as Prosthetic Antigen Receptors for Redirecting T Cells against Tumor Cells and as Platform for Delivery of Vaccine Adjuvants for Cancer Immunotherapy."
Rachit Shaw, Ph. D., Medicinal Chemistry, 2017, "Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain."
Jake Petersburg, Ph. D., Medicinal Chemistry, 2018, “Targeting Cancer with Prosthetic Antigen Receptor T-cells”.
Aniekan Okon, Ph. D., Medicinal Chemistry, 2018, “Development of Chemical Probes for Intracellular Nucleotide Delivery, Profiling of the Metabolic Fate(s) of Nucleoside Monoester Phosphoramidates and a Nucleotide Mimetic Inhibitor of eIF4E"
Cliff M. Csizmar, MD./Ph.D., Medicinal Chemistry, 2018, “From Ligands to Scaffolds to Cells: Engineered Proteins for Studying and Controlling Cellular Recognition"
Harrison West, Ph. D., Medicinal Chemistry, 2019, “Self-assembling phosphoramidate pronucleotides: enzymatic regulation and application towards therapeutic delivery”
Ozgun Kilic, Ph. D., Medicinal Chemistry, 2020, “Targeting EGFR family receptors with CSANs utilizing alternative protein scaffolds”
Alex Strom, Ph. D., Medicinal Chemistry, 2020, “Studies of Histidine Nucleotide Binding Protein Binding and Catalysis”
Ellie Mews, Ph. D. Medicinal Chemistry, 2021, “Directing T Cells with Chemically Self-Assembled Nanorings as an Immunotherapy for Targeting Hematological Malignancies and Solid Tumors”
Yiao Wang, Ph. D., Chemistry, 2022, “Prenylated Chemically Self-Assembled Nanorings: A Versatile Platform for Macro-Chemical Biology”
Maxwell Dillenburg, Ph.D., Medicinal Chemistry, 2023 “Design, Synthesis, and Characterization of Nucleoside Based Probes to Evaluate the Role of Human Histidine Triad Nucleotide Binding Protein 1 in Mu Opioid Receptor and N-Methyl-D-Aspartate Receptor Cross Regulation”
Nicole Mai Bentz, Ph.D., Medicinal Chemistry, 2023, "Harnessing the Synergistic Self-Assembly of G-Quadruplex-Peptide Phosphoramidates: From Elucidating Assembly Mechanisms and Hydrogel Characteristics to Applications in Supramolecular Drug Delivery"
Sean Welter, M.S., Chemistry, 2023, "Bispecific Chemically Self-Assembled Nanorings for Targeted Anticancer Drug Delivery"
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