✍️ Publications
-2025-
May 2025- Congratulations to Patrycja Puchalska for her co-authorship publication, 'Reduced liver mitochondrial energy metabolism impairs food intake regulation following gastric preloads and fasting'
April 2025- Congratulations to Eric Queathem and Puchalska-Crawford group for their publication, 'Ketogenesis mitigates metabolic dysfunction-associated steatotic liver disease through mechanisms that extend beyond fat oxidation'.
April 2025-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'Ketone body supported respiration in murine isolated brain mitochondria is augmented by alpha-ketoglutarate and is optimized by neuronal SCOT expression'.
March 2025-Congratulations to Alisa Nelson and Puchalska-Crawford group for her publication, 'Deciphering Colorectal Cancer–Hepatocyte Interactions: A Multiomics Platform for Interrogation of Metabolic Crosstalk in the Liver–Tumor Microenvironment'.
March 2025-Congratulations to Eric Queathem and Peter Crawford for their co-authorship publication, 'Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes'.
January 2025- Congratulations to Eric Queathem and Puchalska-Crawford group for their publication, 'Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation'.
January 2025-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'Cognitive impairment caused by compromised hepatic ketogenesis is prevented by endurance exercise'.
-2024-
November 2024-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity'.
November 2024-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'Metabolic programs drive function of therapeutic NK cells in hypoxic tumor environments'.
October 2024- Congratulations to Patrycja Puchalska for her publication, 'Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells'.
October 2024- Congratulations to Patrycja Puchalska, Eric Queathem, and Alisa Nelson for their publications, 'Quantification of Total Ketone Bodies in Biological Matrices Using Stable Isotope-Labeled Internal Standards and RP-UHPLC-MS/MS,' and 'Distinguishing Artifactual Fatty Acid Dimers from Fatty Acid Esters of Hydroxy Fatty Acids in Untargeted LC-MS Pipelines'.
August 2024- Congratulations to Kyle Fulghum for leading the review article, 'Ketone Body Metabolism and Cardiometabolic Implications for Cognitive Health,' to be published in the journal npj Metabolic Health and Disease. This article that underscores a collaboration with the Thyfault group at the University of Kansas Medical Center.
May 2024- Congratulations to Alisa Nelson for her publication, 'Gender-based heterogeneity of FAHFAs in trained runners.'
April 2024- Congratulations to Peter Crawford for publishing co-authorship publication, 'Aerobic capacity and exercise mediate protection against hepatic steatosis via enhanced bile acid metabolism'.
January 2024- Congratulations to Patrycja Puchalska for publishing editorial, 'Unraveling the complex connection between ketone bodies and insulin resistance'.
-2023-
December 2023- Congratulations to Puchalska- Crawford Lab for publishing 'Metabolic Messengers: ketone bodies" in the Journal of Nature Metabolism'.
November 2023-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'Ketone bodies in right ventricular failure: A unique therapeutic opportunity'.
July 2023-Congratulations to Puchalska-Crawford group for their co-authorship publication, 'ATP-gated potassium channels contribute to ketogenic diet-mediated analgesia in mice'.
September 2023- Congratulations to Peter Crawford for publishing co-authorship publication, 'Ketone ester administration improves glycemia in obese mice'.
September 2023- Congratulations to Patrycja Puchalska and Peter Crawford for publishing co-authorship publication, 'Ketolysis drives CD8+ T cell effector function through effects on histone acetylation'.
July 2023- Congratulations to Peter Crawford for publishing co-authorship publication, 'Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells'.
August 2023- Congratulations to Kyle Fulghum for publishing, 'Coordinated Metabolic Responses Facilitate Cardiac Growth in Pregnancy and Exercise.'
July 2023- Congratulations to Puchalska-Crawford group for their co-authorship publication, 'Ketolysis is required for the proper development and function of the somatosensory nervous system'.
July 2023- Congratulations to Peter Crawford for publishing co-authorship publication, 'Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells'.
May 2023- Congratulations to Puchalska-Crawford group for their co-authorship publication with Wernimont group, 'Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner'.
May 2023- Congratulations to Peter Crawford for publishing co-authorship publication, 'Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase'.
May 2023- Congratulations to Puchalska-Crawford group for their co-authorship publication with Wernimont group, 'Mitochondrial citrate metabolism and efflux regulate BeWo differentiation'.
March 2023- Congratulations to Patrycja Puchalska and Peter Crawford for publishing co-authorship publication, 'Ketones and the Heart: Metabolic Principles and Therapeutic Implications'.
January 2023- Congratulations to Puchalska-Crawford group for their co-authorship publication with Hughey group, 'Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice'.
January 2023- Congratulations to Peter Crawford for publishing co-authorship publication, 'The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase'.
🏆 Recent Fellowships and Grants
April 2025- Congratulations to Eric Queathem: out of 195 outstanding doctoral candidates from across the University who were nominated, he received a 2025-26 Doctoral Dissertation Fellowship (DDF)!
November 2024- Congratulations to Abdiraham (Abdi) Hayir for receiving postbaccalaureate fellowship through Minnesota Postbaccalaureate Readiness in Metabolism, Endocrinology, and Diabetes (PRIMED) program at the University of Minnesota! A distinct honor!
November 2024- Congratulations to Patrycja Puchalska for receiving a grant as PI entitled, 'Ketone bodies as anabolic and catabolic fuels in the developing fetal and postnatal brain' through Medical School/UMF Assistant Professor Award
August 2024- Congratulations to Patrycja Puchalska for receiving a grant as PI entitled, ‘Central role of ketone body metabolism during embryonic brain development,’ through the MIDB Seed Grant – an Interdisciplinary Faculty Research Award mechanism!
🎓 Lab Member Accomplishments
April 2025- Congratulations to Eric Queathem for receiving the 2025 Charles Carr / William Peterson Award from the BMBB Graduate Program!
April 2025- Congratulations to Kyle Fulghum and Eric Queathem for winning Hebbel Day Awards in 2025!
March 2025- Congratulations to Eric Queathem for his selection as one of only four awardees for the Medical School's Beatrice Z. Milne and Theodore Brandenburg Award! A distinct honor!
October 2024- Congratulations to Kyle Fulghum for scholarship award to attend Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, hosted by Vanderbilt University.
June 2024- Congratulations to Eric Queathem and Alisa Nelson for taking home Hebbel Research Day poster awards!!!
June 2024- Congratulations to Eric Queathem on his second-place finish in the IBP Visscher symposium!
January 2024- Congratulations to Patrycja Puchalska for winning the Scientific Poster Award at the Metabolic Health Summit 2024. Wonderful presentations also by Kyle Fulghum, Alisa Nelson, and Eric Queathem!
May 2023- Congratulations to Eric Queathem for passing his BMBB qualifying exam. You are now officially a PhD candidate!
🧑🔬 New Lab Members
April 2025- Formal welcome to Senali Dansou, MSTP student into Puchalska-Crawford Lab for his thesis studies!
May 2025- Welcome to Ruusu (Rose) Ankeriasniemi in the group! A recent graduate from Gettysburg College!
January 2024- Welcome to Abdiraham (Abdi) Hayir! A recent graduate from Macalester College!
May 2023- Welcome Kyle Fulghum, new postdoctoral fellow to the Crawford-Puchalska group, from the lab of Bradford Hill at the University of Louisville!
🗓️ Upcoming or Past Events
May 2025 - Puchalska- Crawford Lab will participate 2025 UMN Diabetes Research Day - Friday, May 30, 2025 Featuring Dr. Carmella Evans-Molina, MD, PhD
April 2025- At IBP’s 8th Annual Undergraduate Research Symposium, Ruusu (“Rose”) Ankeriasniemi and Abdiraham (“Abdi”) Hayir proudly showcased their hard work and innovation through impressive poster presentations— congratulations to both for representing the lab with such distinction!
April 2025- Puchalska- Crawford group participate in DOM Hebbel Research Day!
March 2025- Patrycja Puchalska attended the Central Florida Triangle Metabolism Meeting, where she delivered an oral presentation titled "Novel Paths for Ketone Metabolism Revealed by Diverse Analytical Chemical Approaches."
October 2023- Patrycja Puchalska presented at the Polish Proteomics Society and Polish Society of Metabolomics (PTP). The title of her talk was 'Metabolomics and Lipidomics approaches to reveal disease pathobiology'.
📢 Media and Press Mentions
May 2025- Congratulations to PPC group on being featured in Medical School Newsletter featuring their recent JCI and Sci Adv studies
November 2024- Congratulations to Patrycja Puchalska on being featured in Perspectives (Volume 4, Issue 1) in a four-page article entitled 'Leaders in Health and Science.' Perspectives is a publication of the Minnesota Polish Medical Society.