David Kazadi

Hematology, Oncology & Transplantation Fellow, 2023 - current

Education

B.A., Chemistry and Interdisciplinary Honor Studies — Hunter College of the City University of New York

M.D./Ph.D. — Columbia University Vagelos College of Physicians & Surgeons, New York

Honors & Awards

2017 NIH Clinical Electives Program
2016 CDC Epidemiology Elective Program
2012-15 NIH Ruth L. Kerstein Fellowship

Research

TBD

Publications

Rashidi A, Ebadi M, Rehman TU, Elhusseini H, Kazadi D, Halaweish H, Khan MH, Hoeschen A, Cao Q, Luo X, Kabage AJ, Lopez S, Ramamoorthy S, Holtan SG, Weisdorf DJ, Khoruts A, Staley C. Multi-omics Analysis of a Fecal Microbiota Transplantation Trial Identifies Novel Aspects of Acute GVHD Pathogenesis. Cancer Res Commun. 2024 Jun 10;4(6):1454-1466. doi: 10.1158/2767-9764.CRC-24-0138. PMID: 38767452; PMCID: PMC11164016.
Katoto PD, Muttamba W, Bahizire E, Malembaka EB, Bosa HK, Kazadi DM, Lubambo G, Siangoli FB, Bakamutumaho B, Wayengera M, Mavungu Landu DJ, Mukadi-Bamuleka D, Mbala P, Loeb M, Kirenga B, Muyembe-Tamfum JJ. Shifting transmission patterns of human mpox in South Kivu, DR Congo. Lancet Infect Dis. 2024 Jun;24(6):e354-e355. doi: 10.1016/S1473-3099(24)00287-1. Epub 2024 May 1. PMID: 38703785.
McQuiston JH, Luce R, Kazadi DM, Bwangandu CN, Mbala-Kingebeni P, Anderson M, Prasher JM, Williams IT, Phan A, Shelus V, Bratcher A, Soke GN, Fonjungo PN, Kabamba J, McCollum AM, Perry R, Rao AK, Doty J, Christensen B, Fuller JA, Baird N, Chaitram J, Brown CK, Kirby AE, Fitter D, Folster JM, Dualeh M, Hartman R, Bart SM, Hughes CM, Nakazawa Y, Sims E; CDC 2024 Clade I Mpox Response Team; Christie A, Hutson CL. U.S. Preparedness and Response to Increasing Clade I Mpox Cases in the Democratic Republic of the Congo - United States, 2024. MMWR Morb Mortal Wkly Rep. 2024 May 16;73(19):435-440. doi: 10.15585/mmwr.mm7319a3. PMID: 38753567; PMCID: PMC11115432.
Rashidi A, Ebadi M, Rehman TU, Elhusseini H, Kazadi D, Halaweish H, Khan MH, Hoeschen A, Cao Q, Luo X, Kabage AJ, Lopez S, Ramamoorthy S, Holtan SG, Weisdorf DJ, Khoruts A, Staley C. Multi-omics analysis of a fecal microbiota transplantation trial identifies novel aspects of acute graft-versus-host disease pathogenesis. Cancer Res Commun. 2024 May 20. doi: 10.1158/2767-9764.CRC-24-0138. Epub ahead of print. PMID: 38767452.
Laverdure S, Kazadi D, Kone K, Callier V, Dabitao D, Dennis D, Haidara MC, Hunsberger S, Mbaya OT, Ridzon R, Sereti I, Shaw-Saliba K; InVITE Study Team. SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali. Int J Infect Dis. 2024 May;142:106985. doi: 10.1016/j.ijid.2024.106985. Epub 2024 Feb 28. PMID: 38417612.
Katoto PD, Muttamba W, Bahizire E, Malembaka EB, Bosa HK, Kazadi DM, Lubambo G, Siangoli FB, Bakamutumaho B, Wayengera M, Mavungu Landu DJ, Mukadi-Bamuleka D, Mbala P, Loeb M, Kirenga B, Muyembe-Tamfum JJ. Shifting transmission patterns of human mpox in South Kivu, DR Congo. Lancet Infect Dis. 2024 May 1:S1473-3099(24)00287-1. doi: 10.1016/S1473-3099(24)00287-1. Epub ahead of print. PMID: 38703785.
A. Rashidi, M. Ebadi, T.U. Rehman, H. Elhusseini, D. Kazadi, H. Halaweish, M.H. Khan, A. Hoeschen, Q. Cao, X. Luo, A.J. Kabage, S. Lopez, S.G. Holtan, D.J. Weisdorf, A. Khoruts, C. Staley. 2023. Potential of Fecal Microbiota Transplantation to Prevent Acute GVHD: Analysis from a Phase II Trial. Clin. Cancer Res. 29(23):4920-4929.
A. Rashidi, M. Ebadi, T.U. Rehman, H. Elhusseini, D. Kazadi, H. Halaweish, M.H. Khan, A. Hoeschen, Q. Cao, X. Luo, A.J. Kabage, S. Lopez, S.G. Holtan, D.J. Weisdorf, A. Khoruts, C. Staley. 2023. Randomized Double-Blind Phase II Trial of Fecal Microbiota Transplantation Versus Placebo in Allogeneic Hematopoietic Cell Transplantation and AML. J. Clin. Oncol. 41(34):5306-5319.
A. Rashidi, M. Ebadi, T.U. Rehman, H. Elhusseini, D. Kazadi, H. Halaweish, MH Khan, A. Hoeschen, Q. Cao, X. Luo, A.J. Kabage, S. Lopez, S.G. Holtan, D.J. Weisdorf, A. Khoruts, C. Staley. 2023. Potential of fecal microbiota transplantation to prevent acute graft-versus-host disease: Analysis from a phase 2 trial. Clin. Cancer Res. Online ahead of print.
D. Kazadi , D. Zychowski, C. Skipper, P. Teravskis, G.T. Hansen, E.E. Ordaya. 2022. Clostridium Tetani Bacteremia From a Suspected Cutaneous Source. Cureus Mar 4:14(3):e22848. PMID: 35382192
Kazadi D, Lim J, Rothschild G, Grinstein V, Laffleur B, Becherel O, Lavin MJ, Basu U. 2020. Effects of senataxin and RNA exosome on B-cell chromosomal integrity. Heliyon 6(3):e03442. PMID: 321953833
Pefanis E, Wang J, Rothschild G, Lim J, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U. 2015. RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity. Cell 161(4):774-89. PMID: 25957685
Lim J, Giri PK, Kazadi D, Laffleur B, Zhang W, Grinstein V, Pefanis E, Brown LM, Ladewig E, Martin O, Chen Y, Rabadan R, Boyer F, Rothschild G, Cogné M, Pinaud E, Deng H, Basu U. 2017. Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. Cell 69(3):523-537. PMID: 28431250
Keim C, Kazadi D, Rothschild G, Basu U. 2013. Regulation of AID, the B-cell genome mutator. Genes Dev. 27(1):1-17. PMID: 23307864
Sun J, Keim CD, Wang J, Kazadi D, Oliver PM, Rabadan R, Basu U. 2013. E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells. Genes Dev. 27(16):1821-33. PMID: 23964096

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