Scan mechanisms based on parametric resonance, thin-film PZT, and electrothermal working principles. Actuator designs to control movement of mechanical structures, such as reflectors, based on sensor input. Mechanisms for feedback and control.
Scan mechanisms based on parametric resonance, thin-film PZT, and electrothermal working principles. Actuator designs to control movement of mechanical structures, such as reflectors, based on sensor input. Mechanisms for feedback and control.
Use of flexible optical fibers to collect real time images of cells and tissues inside a living body with sub-cellular resolution using confocal, multi-photon, and photoacoustic imaging modalities. Concepts include state-of-the-art lens design, alignment fixtures, and packaging strategies.
Application of flexible fiber-coupled photoacoustic imaging instruments to perform functional, molecular, metabolic, and histologic imaging using endogenous contrast and for molecular and neuronal imaging using exogenous contrast.
Basic concepts in image acquisition, including motion artifact mitigation, denoising, and frame rate control. Image enhancement, including contrast optimization, artifact removal, and noise reduction. Image segmentation, including feature detection and pattern recognition.
Artificial neural networks (ANNs), including input, hidden, and output layers; features extraction; image segmentation; region labeling; training models; alternative architectures; network validation and optimization; real time clinical interpretation of in vivo images; digital pathology.