About Us

The primary goal of the U-M Cardiovascular Regeneration Core Laboratory is to ensure successful use of hiPSC based cellular technology for the Michigan research community. The Directors of the Frankel Cardiovascular Center recognized the need for our laboratory and have been instrumental in the establishment of the Cardiovascular Regeneration Core Laboratory.

Contact Us

Email us today at cvcregenerationcore@gmail.com to get started on your patient-specific research projects or visit our Contact Us page for more information.

Key Personnel

Todd J. Herron, PhD, Director

Associate Research Scientist, Molecular and Integrative Physiology Associate Research Scientist, Internal Medicine, Medical School

Dr. Herron is Cardiovascular Regeneration Core Director and Associate Research Scientist, Molecular and Integrative Physiology and Associate Research Scientist, Internal Medicine, Medical School.

Dr. Herron was born in Frankfort, Indiana and was raised in Virginia Beach, VA. After graduation from First Colonial High School he attended Culver Stockton College where he was an NAIA Football Academic All American and obtained a BS in Biology and Chemistry in 1997.


Key Personnel

Todd Herron, PhD (continued)

He obtained a PhD from the University of Missouri-Columbia in the laboratory of Dr. Kerry McDonald. Upon graduation in 2002 Dr. Herron joined Kings College London in the laboratory of Dr. Jon Kentish and completed an MRC sponsored postdoctoral fellowship. In each of these laboratories training focused on molecular regulation of single cardiomyocyte contractile function.

In 2004 Dr. Herron joined the University of Michigan research community as a research fellow on the prestigious Cardiovascular Research Training Grant (T32) and also competed successfully for an individual NIH NRSA Award (F32). This NIH sponsored postdoctoral fellowship period was conducted in the laboratory of Dr. Joseph Metzger, a pioneer in the field of gene transfer for molecular cardiology.

In 2007 Dr. Herron had the fortuitous opportunity to join the UM Center for Arrhythmia Research and began a fruitful collaboration with Dr. Jose Jalife. Dr. Herron's extensive molecular cardiology training thus spans the spectrum of cardiac function from excitation (action potential and electrophysiology) to contraction (force development). In 2010 Dr. Herron completed training on Human Pluripotent Stem Cell Culture Methods at WiCell Research Institute in Madison, WI. Since then his research has focused on using hiPSCs and hESCs to generate patient specific models of inherited heart disease and also to establish hiPSC-CM based cardiotoxicity screening platforms in vitro.

Contact Todd Herron:


Andre Monteiro da Rocha, PhD, DVM

Dr. Rocha joined the group in 2015 as Research Laboratory Specialist Intermediate. Andre was born and raised in Sao Paulo, Brazil were he attended the Veterinary School of the University of Sao Paulo (FMVZ-USP)

Andre Monteiro da Rocha, PhD, DVM (continued)

His interest in research led him to join the Department of Animal Reproduction of FMVZ-USP as an veterinary student and after graduation (1999) he completed his training at the same department, obtaining a Master's in Animal Reproduction (2001) and a Ph.D. in Animal Reproduction (2005).

He worked as a researcher for the biggest human assisted reproduction clinic in South America for 5 years before joining the University of Michigan as a research fellow at UM MStem Cell Laboratories in 2011. In 2012, Andre was part of a collaboration between MStem Cell Laboratories and the Center for Arrhythmia Research to study the developmental effects of a mutation causal of Hypertrophic Cardiomyopathy and started working closely to Dr. Herron's group. Upon the completion of his post-doctoral training he joined Dr. Herron's team.

Contact Andre Monteiro da Rocha:


Jeffery Creech, BA

Jeffery Creech, BA is a Research Laboratory Tech Associate with an appointment in Internal Medicine-Cardiology.

Jeff was born and raised in Brooklyn, MI where he graduated from Columbia Central High School. Jeff is a recent (2016) graduate of Spring Arbor Universitywhere he received a BA in Biology and Psychology with a minor in Chemistry. He has also performed original research on the screening and development of antimicrobial compounds as part of his education. In 2014, he completed a virology internship at the University of Texas Medical Branch (UTMB) in the lab of Dr. Barry Rockx where he was co-authored on a manuscript analyzing the cross-reactivity of monoclonal antibodies against all known Ebola viruses. Jeff joined the Core laboratory in January 2017 and has received training on human pluripotent stem cell derivation, maintenance, and differentiation to cardiovascular cells.

Contact Jeffery Creech:

Key Collaborators

Katherine F. Campbell, PhD is a Postdoctoral Fellow in the Department of Internal Medicine working in the Center for Arrhythmia Research, directed by Dr. Jose Jalife. Dr. Campbell is originally from NJ and obtained her undergraduate degree in Physics from Reed College in Portland, Oregon in 2004. As her interests shifted from physics to biophysics, she worked as a lab tech at Oregon Health and Sciences Institute and took classes at Portland State University in biology to round out her training before pursuing a PhD. Dr. Campbell began her PhD at SUNY Upstate Medical University in 2007 and joined the Jalife lab in the Department of Pharmacology. In 2008 the Jalife lab had the opportunity to make the move to the University of Michigan. This transition allowed Dr. Campbell to complete her MS in Pharmacology in 2008 working with Dr. Kalifa on the role of regional atrial ischemia in atrial fibrillation. Dr. Campbell joined the department of Molecular and Integrative Physiology at the University of Michigan and went on to complete her PhD in 2013. During her PhD she worked with Dr. Berenfeld on the role of regional ion channel heterogeneities in arrhythmogenesis and developed novel cardiac culturing techniques. Upon completion of her PhD she began a postdoc in the Jalife lab working with Dr. Herron developing a 3D stem cell derived cardiomyocyte model to investigate the mechanisms of inherited cardiomyopathies.

Contact

The Cardiovascular Research Core is housed in the North Campus Research Complex (NCRC) in the Cardiovascular Research Center. Our primary objective is to ensure successful use of hiPSC based cellular technology for the Michigan research community. The Directors of the Frankel Cardiovascular Center recognized the need for our laboratory and have been instrumental in the establishment of the Cardiovascular Regeneration Core Laboratory.

Contact Us

Email us today at cvcregenerationcore@gmail.com to get started on your patient-specific research projects or visit our Contact Us page for more information.