REFRESH THIS PAGE regularly. It is updated often, especially on class days.
Textbook: https://drive.google.com/file/d/17YwA7H1OfOMv1iOH5QHddfqngmy_21Di/view?usp=sharing
Updated textbook solutions: https://drive.google.com/drive/folders/16HjnzB9UUN_jssTPvW4x1H0f2r8qYONp?usp=sharing
Monday February 5, 2024
Dissolving things in water activity
Give out textbooks
About the course
About the teacher: https://docs.google.com/presentation/d/1fFpJeaKtZyeAsOtrX7kbQXxL6wNilrtJYXslkVwzWGc/edit?usp=sharing
Course information: https://docs.google.com/document/d/1MhUWDfH5HwxsuHKtk33--VWYVxPs1rWmZkxFNnL29qI/edit?usp=sharing
Please tell the teacher about yourself: https://docs.google.com/forms/d/e/1FAIpQLSejeua4eQEJ_HO9p6tshMz4Wv7IGVvpy3Z-16F2OGlkw7BLxw/viewform?usp=sf_link
Who plans to write the AP exam?
Discussion question: "Is Water Sticky or Slippery?" Provide many examples.
Homework: Read Chapter 1.1 page 14-17, from "Polar Molecules" to "Hydrolysis Reactions" (skip neutralization and redox reactions).
Tuesday February 6
Did anyone not fill out "about me" from last day?
Safety training on Brightspace
Hydrogen bonding - 9 min https://www.youtube.com/watch?v=PyC5r2mB4d4
Optional Videos:
https://www.youtube.com/watch?v=HVT3Y3_gHGg - Water Crash Course 11 min
https://www.youtube.com/watch?v=3jwAGWky98c - Properties of Water 6 min
https://www.youtube.com/watch?v=7lhQuNpMo8g - Buffers 3 min
https://www.youtube.com/watch?v=rIvEvwViJGk - Anderson pH and Buffers 5 min
https://www.youtube.com/watch?v=FTrFKPaOpm8 - Adhesion, cohesion, surface tension 7 min
Homework: Read Chapter 1.2 properties of water. Skip the last section "Neutralization Reactions and Buffers". Answer questions 1-8.
Wed February 7
Verify you can see the textbook answers
Water lab
https://docs.google.com/document/d/1rfHOztfrchTHePIB97qBZaDV0-SBwqjhLtwkmIzyMpI/edit?usp=sharing
Take up homework
Water Test (graded - counts for marks) on Monday
Thu February 8
Take up lab and questions from it
Dissolving molecules lab (from page 7 of textbook)
Discuss chapter that was read and answer questions.
Water kahoots
https://create.kahoot.it/details/b08eca10-3a38-4602-9df4-c4defdc83757?authuser=0
Watched in class: Carbon - 2 min https://www.youtube.com/watch?v=ULiLt2rtpAg
Good Carbon and functional groups video, 8 min: https://www.youtube.com/watch?v=jHDxHPrbEcA
Start functional groups booklet. 7 pages in functional groups book. https://drive.google.com/file/d/1eW2spXhTtVypjqgytCUtCtRbqJF4qnjR/view?usp=sharing
Homework: Read chapter 1.3
Fri Feb 9
Check who has done safety training
Take up homework
Water Kahoot https://create.kahoot.it/details/8725a35b-ce22-4c39-a211-1256d11dc71e?authuser=0
Practice test: https://docs.google.com/forms/d/e/1FAIpQLSepS5plH6CG8QUouIqPtAjEnT0pZX4wQZFVNa_D4Qzb0icsKg/viewform?usp=sf_link
Water test next class. Study the textbook chapter (not buffers or pH), the textbook questions, the presentation, and the lab.
Class discussion of a question - how do hydrogen bonds lead to this property shown?
Review questions:
Explain the molecular structure of water, including sharing of electrons.
Explain how water's polar nature leads to adhesion and cohesion
List the biologically important properties of water we studied
Explain how water dissolves things (acts a solvent)
Optional video on functional groups - 4 min https://www.youtube.com/watch?v=3rqmBK1VA_
Carbon Presentation: https://docs.google.com/presentation/d/1NgcrnpUV-XHhcLbaKyGr5DDlEPGVaie3/edit?usp=sharing&ouid=116878137606048956010&rtpof=true&sd=true
Homework: Read chapter 1.3 if not completed yesterday, complete questions 1-4, 6-9.
Monday February 12, 2024
Water test
Lesson - Carbohydrates handout:https://drive.google.com/file/d/1tTgmVlZEkmplyQJdMzx1Js_GxyaWeZkx/view?usp=sharing
Handout with class notes: https://drive.google.com/file/d/13Tvbb59PXRePiOw7eBfDH-foEcdpNs0p/view?usp=sharing
Option: Carbohydrates PPT (1.4): https://drive.google.com/file/d/1bUyRYnkyNmSPcIsZaJ2v-WD3fookod7T/view?usp=sharing
Homework: Read carbohydrate part of 1.4, answer page 38 # 1a. b. 5, Page 64 # 6, 11, 13, 15, 53, 72,
Tuesday Feb 13
Amoeba sisters biomolecules (2023 version) - 7 min https://www.youtube.com/watch?v=1Dx7LDwINLU
TedEd - What are carbohydrates: https://www.youtube.com/watch?v=wxzc_2c6GMg
Add Hydroxyl group page to functional groups book. Draw glucose and highlight groups
Practice drawing glucose molecules
Molymod kits in pairs
1. Build glucose
2. Rearrange to fructose
3. Do dehydration synthesis of glucose and fructose. You may need to pair with another group. Name the new molecule.
Optional videos:
Video: carbohydrates Mr. Anderson 8 min https://www.youtube.com/watch?v=_zm_DyD6FJ0
Molecules of life - Mr. Anderson - 10 min: https://www.youtube.com/watch?v=QWf2jcznLsY
Continue homework: Page 38 # 1a. b. 5, Page 64 # 6, 11, 13, 15, 53, 72,
Wed 14th
Carbohydrates Kahoot: https://create.kahoot.it/details/013e1c6f-1d0f-4fd5-b56c-ec59eb25436f
Talk about homework
Return water tests
New topic: Lipids
Videos:
Lipids video 7 min: https://www.youtube.com/watch?v=5BBYBRWzsLA
Lipids and Nucleic Acids combined handout: https://docs.google.com/document/d/1-dR5TvfH0_tCPS355Sv0w0LjHDPuIsPMAkMD9V5eUoo/edit?usp=sharing
Lipids handout with note written on it: https://drive.google.com/file/d/1Txe_6irzvtaMNDnLo_q0Cy2ITEIT5djC/view?usp=sharing
Optional lipids presentation: https://docs.google.com/presentation/d/1T6M9-2olPT5Cqs1KeUctFhPwqjoRDGz3coBkyQFePZw/edit?usp=sharing
Homework:
Read lipids (pages 33-37). Answer page 38 #4,6,7 Page 64 #12
Thu February 15th, 2024
Questions from homework
Proteins Video:
Amoeba sisters proteins. Watched in class. https://www.youtube.com/watch?v=hok2hyED9go
Bozeman Proteins - 9 min: https://www.youtube.com/watch?v=2Jgb_DpaQhM&list=PL-h68ACsUTpfMAvpYm5t8VvKZNM6crnsu
Ricochet Science 3 min: https://www.youtube.com/watch?v=AUMJwjLXh1M&list=PL6CmKEk-VCe9Gu5JwLi30C9pxT9-NVkYX&index=5&t=0s
Proteins PPT (1.5): https://docs.google.com/presentation/d/1dpEXGH7Y6cLqn8KYmrY2UU59VN0wQ5sQACj70txysL4/edit?usp=sharing
Handout: https://docs.google.com/document/d/14yUS3ZVMoGIAIf7y9CwzHZhKqjr3kpoCIcMlLdXURPg/edit?usp=sharing
Add carboxyl group to our book
Add amino group to book - draw amino acid, draw dehydration synthesis
Add Suflhydryl to book - draw cysteine, sketch a disulfide bridge in a protein
Add Methyl group to books. Draw alanine which has a single methyl group as the -R group.
Homework:
Read 1.5 section on proteins
Page 47 #1-7, online research 13, 14
Friday February 16, 2024
Proteins day 2
Watched: explanation of gluten in cooking: https://www.youtube.com/watch?v=zDEcvSc2UKA
Isolating gluten activity:
40g flour with 20g water, knead ~5 min until smooth (more water can be added if necessary, but if more flour is added it must be weighed and added to the total), sit at least 5 minutes, wash until water is less milky, leave to dry on tinfoil, weigh next day
Not watched:
Video of isolating and cooking gluten: https://www.youtube.com/watch?v=_9oU-FReopE
TedEd on gluten: https://www.youtube.com/watch?v=uEM2iDT-VAk
Homework:
complete homework assigned yesterday
Formative Quiz (does not count for grade) on Water, Carbohydrates, Lipids, Functional Groups
https://forms.gle/4ky7tNBZPht2m1EZ7
Fill out functional groups books: https://drive.google.com/file/d/1eW2spXhTtVypjqgytCUtCtRbqJF4qnjR/view?usp=sharing
Add carboxyl group to our book
Add amino group to book - draw amino acid, draw dehydration synthesis
Add Suflhydryl to book - draw cysteine, sketch a disulfide bridge in a protein
Add Methyl group to books. Draw alanine which has a single methyl group as the -R group.
Protein folding simulation: https://www.labxchange.org/library/items/lb:LabXchange:a664fc10:lx_simulation:1
Optional videos:
Skipped this year: Bozeman Proteins - 9 min: https://www.youtube.com/watch?v=2Jgb_DpaQhM&list=PL-h68ACsUTpfMAvpYm5t8VvKZNM6crnsu
A millisecond of protein folding: https://www.youtube.com/watch?v=gFcp2Xpd29I
How to unboil an egg: https://www.youtube.com/watch?v=CHMY4G9gTPA
Tuesday Feb 20, 2024
Unit 1 test - Tuesday Feb 27
Safety training check
Questions from homework
Check homework, including functional groups book
Not done in class - Lipids Kahoot: https://create.kahoot.it/details/lipids/1a689039-1b4c-46ba-b254-5a19c86ee669
Watched in class - Bozeman Nucleic Acids 8 min: https://www.youtube.com/watch?v=NNASRkIU5Fw
Not watched: Amoeba sisters DNA vs RNA: https://www.youtube.com/watch?v=JQByjprj_mA
Nucleic acid note: https://drive.google.com/file/d/1Txe_6irzvtaMNDnLo_q0Cy2ITEIT5djC/view?usp=sharing
Nucleic Acids presentation: https://docs.google.com/presentation/d/1fhB87v66otapFZKHOku2c9jrCSPcYKezS3qX2waDoqY/edit?usp=sharing
Add phosphate group to our functional groups booklet.
Homework:
Read nucleic acids (pages 45-46). Answer page 47 #8-11
Complete protein note from presentation on Friday
Wed Feb 21, 2024
Weigh flour samples
Videos:
Watched in class: Amoeba Sisters Enzymes with Examples 8 min https://www.youtube.com/watch?v=6EDBlowVST0
Enzymes Bozman 11 min https://www.youtube.com/watch?v=ok9esggzN18
Enzymes Professor Dave 7 min https://www.youtube.com/watch?v=H_1ULIKzwfA
Enzyme song 2 min https://www.youtube.com/watch?v=NdMVRL4oaUo
Enzymes PPT
https://docs.google.com/presentation/d/1TVDQlmoFWXMQfaooGZImDC-Yu5JT4zHLkgQ8H1djzp0/edit?usp=sharing
Define inhibition - this term comes back again and again in our course - Enzyme inhibition: a decrease in enzyme activity.
Talking about graphs of enzyme function: https://docs.google.com/document/d/1C5dPYxmoLH4macJW4GycA88qPGOrdJKc7Em0b_D9fxc/edit?usp=sharing
Optional further cofactors information: https://www.biologyonline.com/dictionary/coenzyme
Homework: Read chapter 1.7 Enzymes, Questions on page 57 #1-6, 8, 10-13
Thursday Feb 22, 2024
Intro to the Enzyme lab
Prepare for lab. Refine your procedure until you get 4 replicates with minimal variation.
Enzyme lab video (slightly different from our protocol): https://www.youtube.com/watch?v=hs75JmgGW5Y
Demonstration of the reaction by Mr. Wyche for the class
Think about variables you could change to alter the rate of the reaction
Practice writing conclusions based on last year's results from the lab (don't use the word prove, results only support or refute your hypothesis, don't talk about anything you didn't observe in the lab, unless you make it clear you are speculating). Results from past years. Enzyme lab graphs from students Mar 2020 and on https://docs.google.com/document/d/1BeUDF_ZcQ895FVEYP4ZMq3lY0-KqA-IHzjkSUyhbkU4/edit?usp=sharing
Purpose of replicates: https://docs.google.com/document/d/1YVOhyjDz2ORVnx1BnyDXFze88wa6jZTfUaI4uNBjALU/edit?usp=sharing
Homework:
Important - more practice MC questions - just for practice with the feel of some of the questions: https://drive.google.com/file/d/1Qj1-Hzfc1mKbv3CnaPdhO71VKfdGAGP2/view?usp=sharing
Practice questions answer form: https://docs.google.com/forms/d/e/1FAIpQLSct4viJGiAoqdW4bA0Ol0F6UK3g6Pk60ocexKpolYlYqQjrWw/viewform?usp=sf_link
Answers: https://drive.google.com/file/d/1dpbpsVZnGxFPDmIhHJo7WzrdIFMaCTVL/view?usp=sharing
Friday February 23
Review Assigned
Enzyme Gizmo?
Review ideas :
About the unit test: https://docs.google.com/document/d/1AtdIoRz6W4cs762an99vUvvdRK0BKLdVYPzloTAtvmM/edit?usp=sharing
Self quiz page 63 (skip #9), Review page 64.
Done in class: Identify the molecule picture kahoot practice quiz: https://create.kahoot.it/details/10b8a102-af9c-41a4-8f13-fc09191a098c
Another good macromolecules review kahoot: https://create.kahoot.it/details/da21c278-a5ee-4f94-8ce7-66c8abbfec41
Lipids Kahoot: https://create.kahoot.it/details/lipids/1a689039-1b4c-46ba-b254-5a19c86ee669
Review kahoot: https://create.kahoot.it/details/f293b8fd-141a-4c17-83ac-998f93a22413
Special Surprise Quiz (not graded): https://drive.google.com/file/d/19rS6cjFcL9oRu16PjpUuktsXaaT7lhnx/view?usp=sharing
Special Surprise Quiz Entry Form: https://docs.google.com/forms/d/e/1FAIpQLSfV8Ge6G2Mu3kgqFv7mPVhv9Gc46uzREuQ9gSA-4oPI2fadmA/viewform?usp=sf_link
Option: build each functional group using moly mod kits
*Review for test:
Draw and label dehydration synthesis of two amino acids joined together
Draw and label the process of dehydration synthesis of disaccharides
Draw and label a glycerol molecule and 3 fatty acids during dehydration synthesis
Monday February 26
In our course, we studied the four major macromolecules. We consider lipids a macromolecule, even though some places do not. However, we do not consider lipids polymers, because they are not long chains of repeating subunits.
Conduct lab
Take up review questions
You do not need to begin to write up the lab - we will do that together after the test. I'll go through the below information after the unit test.
Enzyme lab
Student instructions: https://docs.google.com/document/d/13ug37QBrIYklb1u6vigwX8w38TYR5cBM4Ao1KmxAxcw/edit?usp=sharing
Student example from Nov 2022 (note that their written lab instructions and questions may be different from your class): https://docs.google.com/document/d/1Rs3Bf2f8WSEkXg8zt4DLhmNKDXOev5nPgl7LMBnRj_Q/edit?usp=sharing
Good student exemple from Nov 2020 (note that their written lab instructions may be different from your class): https://docs.google.com/document/d/1pegvVtECNthYmANQIHQ3XNELiCMSU1iVvdmvLcP5A6M/edit?usp=sharing
Conditions tested: Enzyme lab graphs from students Mar 2020 and Sep 2022: https://docs.google.com/document/d/1BeUDF_ZcQ895FVEYP4ZMq3lY0-KqA-IHzjkSUyhbkU4/edit?usp=sharing
Mr. Wyche's data example, done in class after the lab: https://docs.google.com/spreadsheets/d/1ng5VcHZ9eSR6oWs0rrti_O2eVhBVkn_felrjzu5LRaw/edit?usp=sharing
Mr. Wyche's data with error bars example, done in class after the lab: https://docs.google.com/spreadsheets/d/1nunulozdpStEIyrMAzr4gb-7hfWdSE67mkFwXZl9v1c/edit?usp=sharing
Notes to teacher about the lab: https://docs.google.com/document/d/1xyUyITMZjyHvN4boojCbKSwreq4cKKXRFkq-WxP5uFY/edit?usp=sharing
Optional videos:
Option - graph error bars: https://www.youtube.com/watch?v=B-zKcSoYMq0
control video: https://www.youtube.com/watch?v=f_A6o9fUfzc
Easy controls video: https://www.youtube.com/watch?v=7Qj-upbZDHg
Replicates video: https://www.youtube.com/watch?v=TubzzXYN6X8
another replicate video: https://www.youtube.com/watch?v=Exk0OoRG0PQ
Tuesday Feb 27
Test
Extra, old stuff for the teacher:
Notes for next year: https://docs.google.com/document/d/1lhl6r1J0dEo23lTUSRBZRGhWV2im5ZGPsvnx65d7_E0/edit?usp=sharing
Experimental design work sheets - not done this year:
Experimental design worksheets: https://drive.google.com/file/d/1SlVZS9XZlVCFgkz0yPXcXpCQl1w6zj2H/view?usp=sharing
Please answer all the questions. You do not need to conduct any experiments.
Note from feb 2024 for sep 2024 changes: https://docs.google.com/document/d/1fEKZWZoaL22Ed0F-W5ix0em0GcEVIwp5gXitXGqHGes/edit?usp=sharing
Flour experiment
Old water lab: Properties of Water Lab: https://drive.google.com/file/d/17fl0RCJ2rBCfZs9Ag6evsE7un1_1IFO5/view?usp=sharing
combined water lab handout for printing: https://d rive.google.com/file/d/11NouLOuqCcP9_n6xuzMMRvyTb52UA2rW/view?usp=sharing
Lipids video 7 min:
https://www.youtube.com/watch?v=5BBYBRWzsLA
Lipids PPT (1.4):https://docs.google.com/presentation/d/1FbueItPZkxpYnGxq0Q54bKKIOwHu1pYTv5x5GHk1FVg/edit?usp=sharing
Lipids note:https://docs.google.com/document/d/12yC4-k-GK-mYJ2MiassYMNsSag5XDfCmS2Q1EAV6r70/edit?usp=sharing
Nucleic Acid PPT:
https://docs.google.com/presentation/d/1thsF8-OfXIEOpMrjx_cjckGU6bMarf_M03UM9vfJfb0/edit?usp=sharing
Nucleic Acid Note:
https://docs.google.com/document/d/1fxVHtxcQ5eJKXQz-Rsdl7oXBBLUYMhf3wXFPpKUFM_M/edit?usp=sharing
Add phosphate group to our functional groups booklet.
Moly mod functional groups: https://docs.google.com/document/d/1y9M0GAPQm8L3czpNCRMeVlNZBSBDTd_-yvWDfsXpO2o/edit?usp=sharing
Not done exactly as shown in this assignment, but we build glucose, dehydration synthesis, change to fructose: https://docs.google.com/document/d/1w7rZIyP6OVnX_wYfS18kgcfmMtcJbFQY2gZdECgQ5qE/edit?usp=sharing
More on carbohydrates:
Important to know Beta-glucose vs alpha-glucose for homework: https://sf.ezoiccdn.com/ezoimgfmt/howchimp.com/wp-content/uploads/2021/01/alpha-vs-beta-glucose.jpg?ezimgfmt=rs:371x247/rscb29/ng:webp/ngcb29
Cellulose: https://image.shutterstock.com/image-vector/structural-chemical-formula-cellulose-polymer-260nw-187119629.jpg
Types of glucose polymers: https://ib.bioninja.com.au/_Media/glucose-polysaccharides_med.jpeg
Prepare for tomorrow's lab. Research a macromolecule detection solution and add to the shared powerpoint:
https://docs.google.com/presentation/d/1TWP8F1cPOfigO4V0GDK-2EYRxfOQOpNYpoUna97rojA/edit?usp=sharing
Picture of polymer: https://dr282zn36sxxg.cloudfront.net/datastreams/f-d%3Ad7a6636c8f182ab7b0de4de8bb496853f01da741c143dccda6f6fdec%2BIMAGE_THUMB_POSTCARD_TINY%2BIMAGE_THUMB_POSTCARD_TINY.1
Group discussion about homework
Discuss homework
*Review question #69
Example to discuss: CFTR gene
The CFTR protein is made up of 1,480 amino acids linked together in a chain. Some humans produce a version of the CFTR protein in which phenylalanine (an amino acid) has been deleted from position 508 of the amino acid chain.
https://www.biointeractive.org/classroom-resources/cystic-fibrosis-mechanism-and-treatment
Importance of amino acid sequence to protein function, examples:
Point mutation - changes the amino acid - sickle cell anemia: https://www.medicalhomeportal.org/diagnoses-and-conditions/sickle-cell-disease
Cystic Fibrosis delt508 - removing an amino acid (whole codon)
- video clip 3 min: https://www.youtube.com/watch?v=Qk9Sw7e8fWE
- picture showing a whole codon is deleted: https://www.researchgate.net/figure/The-aF508-deletion-11_fig2_265454554
Optional Videos:
Bozeman Proteins - 9 min: https://www.youtube.com/watch?v=2Jgb_DpaQhM&list=PL-h68ACsUTpfMAvpYm5t8VvKZNM6crnsu
Ricochet Science on Proteins 3 min: https://www.youtube.com/watch?v=AUMJwjLXh1M&list=PL6CmKEk-VCe9Gu5JwLi30C9pxT9-NVkYX&index=5&t=0s
Optional Videos on Statistics for the AP test:
Statistics for Science 11 min: https://www.youtube.com/watch?v=jf9VT4V4aRI&list=PLllVwaZQkS2omBpLjQm_BAQKsQ7lq86ku
Standard Deviation 8 min: https://www.youtube.com/watch?v=09kiX3p5Vek
Standard Error, Error Bars on Graphs, Using Excel 7 min: https://www.youtube.com/watch?v=BwYj69LAQOI
Student's T-Test 11 min: https://www.youtube.com/watch?v=pTmLQvMM-1M
Chi-Squared Test 12 min: https://www.youtube.com/watch?v=WXPBoFDqNVk
Practice questions from a different year (but what we covered this time through will be different than what was covered when this test was assigned): https://drive.google.com/file/d/1EYoNDY8XeYHk8vynpcSmbjexs00xRJC-/view?usp=sharing
Practice test answers: https://drive.google.com/file/d/1xTO3DvCIyRmNgJJ0AUazLT50nGyS9erc/view?usp=sharing
Review Functional Groups - Draw all functional groups, build with molecule kits
Dehydration synthesis Gizmo - please do the quiz assessment questions (not graded)
Water assignment assigned in google classroom assignments (https://docs.google.com/document/d/1vEDIFFDgOKXRJu8eR4ox-qiaqI-o1t6Ol9bExwjXgKE/edit?usp=sharing_
Gizmo - Sticky Molecules - Join Gizmo - class code: C9MNJ4
We don't need to do the whole investigation or fill out any forms. Just play with the experiment, and then complete the multiple choice at the bottom. If technical problems mean you can't join the gizmo, don't worry about it. We will figure out the issues on Monday.
Complete gizmo multiple choice questions
Egg protein denaturing activity: https://askabiologist.asu.edu/activities/breaking-proteins#:~:text=Alcohol.,protein%20would%20bond%20to%20itself.