Development of a PoC Device for Comprehensive Hemostatic Assessment
Team Members:
Viha Ukani
Riya Varma
Mentors:
Asish Koruprolu
Dr. Drew Hall
Abstract
This research investigates an impedance-based time measurement technique to assess hemostatic parameters, namely blood coagulation time. An impedance marker for coagulation rate was identified and demonstrated by initiating the cascade with different activators. Testing of several measurement setups in a simulation environment optimized electrode placement for the amplification of differences in impedance measurements of non-clotting and clotting blood. The measurement technique uses multiplexed current to obtain dual impedance measurements and enhance biomarker visibility. The final prototype forms the basis of a point-of-care (PoC) diagnostic device, offering better accessibility and affordability in settings where monitoring clotting time is crucial, such as guiding surgical interventions and monitoring anticoagulant therapy.
Abet Addendum
Viha Ukani
Riya Varma
The Team