原著論文

Rresearch article (mainly worked in our laboratory)

2026

High-speed atomic force microscopy reveals a surface-catalyzed elongation mechanism of the fungal functional amyloid hydrophobin RolA

Proc. Natl. Acad. Sci., 2026, 123(7):e2523502123. (doi: 10.1073/pnas.2523502123.)

Takahashi N., Kimura T., Terauchi Y., Tanaka T., Abe N., Yoshimi A., Nakayama W. T., Abe K.


2025

Improved Mixing Properties of Stirred Fermentation of an Aspergillus oryzae Hyphal Dispersion Mutant

Biotechnology and Bioengineering, 2025, 122:2389–2399 (DOI: 10.1002/bit.70004)

Shunya Susukida, Ken Miyazawa, Hikaru Ichikawa, Kiyoaki Muto, Akira Yoshimi, Toshitaka Kumagai, Yoshikazu Kato, and Keietsu Abe


Presence of isomaltose transporters in Aspergilli demonstrated through nuclear translocation assays of the transcription factor AmyR

Bioscience, Biotechnology, and Biochemistry, 2025, 89:1391–1399 (DOI: 10.1093/bbb/zbaf085)

Shoki Fujita, Da Min Jeong, Takahiro Shintani and Katsuya Gomi


Elucidation of the structure and molecular mechanisms of the aspartate antiporter

Communications Biology, 2025, 8:1359 (doi: 10.1038/s42003-025-08676-7)

Nanatani K, Guan L, Kanno R, Kawabata T, Watanabe S, Katsube S, Hariharan P, Hidaka M, Yamanaka T, Toda K, Fujiki T, Kunii K, Miyamoto A, Chiba F, Ogasawara S, Murata T, Inaba K, Mitsuoka K, Abe K, Yamamoto M, Koshiba S, 


Using pure oxygen aeration to increase recombinant protein production by an Aspergillus oryzae hyphal dispersion strain

Journal of Bioscience and Bioengineering, 2025, 141(2):98-107 (doi: 10.1016/j.jbiosc.2025.10.011. )

Ishibashi T, Susukida S, Muto K, Miyazawa K, Zhang S, Yoshimi A, Tabata E, Abe K


2024

Glucose-induced endocytic degradation of the maltose transporter MalP is mediated through ubiquitination by the HECT-ubiquitin ligase HulA and its adaptor CreD in Aspergillus oryzae

Fungal Genetics and Biology, 2024, 15;173:103909.

Shoki Fujita, Hinako Tada, Yuka Matsuura, Tetsuya Hiramoto, Mizuki Tanaka, Takahiro Shintani and Katsuya Gomi


Construction of self-cloning Aspergillus oryzae strains with high production of multiple biomass-degrading enzymes on solid-state culture

Journal of Bioscience and Bioengineering, 2024, 137(3):204-210.

Satoko Senoo, Tomoko Shintani, Shoko Nieda, Takahiro Shintani, Masahiro Kariyama and Katsuya Gomi


Thermostability optimization of the aspartate/alanine transporter from Tetragenococcus halophilus

Journal of Biochemistry, 2024, 175:439-446.

Kunii K, Yamanaka T, Miyamoto A, Nanatani K, Abe K


2021

Crucial role of the intracellular α-glucosidase MalT in the activation of the transcription factor AmyR essential for amylolytic gene expression in Aspergillus oryzae

Bioscience, Biotechnology, and Biochemistry, 2021, 85(9): 2076–2083.

Takanori Ichikawa, Mizuki Tanaka, Takayasu Watanabe, Sitong Zhan, Akira Watanabe, Takahiro Shintani and Katsuya Gomi


Expression profiles of amylolytic genes in AmyR and CreA transcription factor deletion mutants of the black koji mold Aspergillus luchuensis

Journal of Bioscience and Bioengineering, 2021, 132(4): 321–326.

Wataru Hashimoto, Hiraku Arai, Osamu Mizutani, OsamuYamada, Takahiro Shintani and Katsuya Gomi


2020

Alternative transcription start site of the enolase-encoding gene enoA are stringently used in glycolytic/gluconeogenic conditions in Aspergillus oryzae.

Current Gnetics, 2020, 66: 729-747.

Taishi Inoue, Hiroki Toji, Mizuki Tanaka, Mitsuru Takama, Sachiko Hasegawa-Shiro, Yuichi Yamaki, Takahiro Shintani and Katsuya Gomi


Review

2026

糸状菌(カビ)の液体培養におけるスケールアップ技術の開発, 第10章バイオリアクターによる食品 化粧品の生産, 第4節「バイオリアクターによる大量培養と後工程の最適化」

技術情報協会 pp497-504 , 2026

薄田隼弥, 宮澤拳, 吉見啓, 阿部敬悦


2025

麴菌の細胞壁:その構造と役割, 制御, 応用展開

応用糖質科学 15:1-14, 2025 (査読あり, 応用微生物学分野と連携)

吉見 啓, 宮澤 拳, 薄田隼弥, 岡 拓二, 阿部敬悦, 


畜産飼料への応用を目指した複数のバイオマス分解酵素を高生産するセルフクローニング麴菌株の造成

日本醸造協会誌,120:160–167, 2025(査読あり, 真核微生物学分野と連携)

妹尾 佐都子,新谷 尚弘,五味 勝也


「発酵・醸造の新展開」金内誠 監修. 

(麴菌の細胞壁表層多糖の制御による新たな糸状菌液体培養技術の開発 (第一編 第1章 第4節)). 

NTS. 41-48, 2025 (査読なし, 応用微生物学分野と連携)

阿部敬悦, 薄田隼弥, 宮澤 拳, 吉見 啓. 


糸状菌の細胞表層界面活性タンパク質~ハイドロフォビンの性質とその応用, 

B&I 83:444-450, 2025 (査読あり, 応用微生物学分野と連携)

阿部敬悦, 田中拓末, 寺内裕貴, 高橋尚央. 


Biological and biochemical studies on cell surface functions in microorganisms used in brewing and fermentation industry

Bioscience, Biotechnology, and Biochemistry, 2025, 89 (5): 649-667-82. (DOI: 10.1093/bbb/zbaf020), * Award Review

Keietsu Abe


麹菌のデンプン分解―やる気スイッチはどこにあるのか―

生物工学会紙, 2025, 第103巻, 4号: 167. (DOI: 10.34565/seibutsukogaku.103.4_167)

藤田 翔貴


2024

バイオものづくりプロジェクト(6)バイオものづくり技術 麴菌プラットフォームの開発. 

バイオサイエンスとインダストリー. 82, 2024

堀口博文, 加藤好一, 阿部敬悦.


菌糸分散型変異を用いる新たな糸状菌液体培養技術~麹菌を例に

生物工学会紙, 2024, 第102巻, 8号: 406-409. (DOI: 10.34565/seibutsukogaku.102.8_406)

阿部 敬悦, 薄田 隼弥, 宮澤 拳, 吉見 啓


Aspergillus Cell Surface Structural Analysis and Its Applications to Industrial and Medical Use

Med. Mycol. J., 2024, 65: 75-82. (DOI: 10.3314/mmj.24.007)

Ken Miyazawa, Takashi Umeyama, Akira Yoshimi, Keietsu Abe, Yoshitsugu Miyazaki


2022

醸造微生物の分子生物工学研究と発酵生産分野への応用技術開発

Molecular biotechnology on brewing microbes and its application to fermentation to industries

生物工学会紙, 2022, 第100巻, 1号: 5-18. (DOI: 10.34565/seibutsukogaku.100.1_5)

五味 勝也 (Katsuya Gomi)


2021

Regulatory mechanisms for amylolytic gene expression in the koji mold Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2019, 83(8): 1385-1401.

Katsuya Gomi


 * 阿部先生の過去の原著論文はこちら